| Molecular hybridization: a useful tool in the design of new drug prototypes C Viegas-Junior, A Danuello, V da Silva Bolzani, EJ Barreiro, CAM Fraga Current medicinal chemistry 14 (17), 1829-1852, 2007 | 1320 | 2007 |
| The methylation effect in medicinal chemistry EJ Barreiro, AE Kümmerle, CAM Fraga Chemical reviews 111 (9), 5215-5246, 2011 | 838 | 2011 |
| From nature to drug discovery: the indole scaffold as a ‘privileged structure’ FR de Sa Alves, EJ Barreiro, CA Manssour Fraga Mini reviews in medicinal chemistry 9 (7), 782-793, 2009 | 641 | 2009 |
| Synthesis and analgesic activity of novel N-acylarylhydrazones and isosters, derived from natural safrole PC Lima, LM Lima, KCM da Silva, PHO Léda, ALP de Miranda, ... European journal of medicinal chemistry 35 (2), 187-203, 2000 | 341 | 2000 |
| Synthesis and anti-inflammatory activity of phthalimide derivatives, designed as new thalidomide analogues LM Lima, P Castro, AL Machado, CAM Fraga, C Lugnier, VLG De Moraes, ... Bioorganic & medicinal chemistry 10 (9), 3067-3073, 2002 | 270 | 2002 |
| Discovery of novel analgesic and anti-inflammatory 3-arylamine-imidazo [1, 2-a] pyridine symbiotic prototypes RB Lacerda, CKF de Lima, LL da Silva, NC Romeiro, ALP Miranda, ... Bioorganic & medicinal chemistry 17 (1), 74-84, 2009 | 240 | 2009 |
| New class of potent antinociceptive and antiplatelet 10H-phenothiazine-1-acylhydrazone derivatives GA Silva, LMM Costa, FCF Brito, ALP Miranda, EJ Barreiro, CAM Fraga Bioorganic & medicinal chemistry 12 (12), 3149-3158, 2004 | 211 | 2004 |
| N-Acylhydrazones as drugs S Thota, DA Rodrigues, PSM Pinheiro, LM Lima, CAM Fraga, EJ Barreiro Bioorganic & medicinal chemistry letters 28 (17), 2797-2806, 2018 | 183 | 2018 |
| Produtos naturais como candidatos a fármacos úteis no tratamento do Mal de Alzheimer C Viegas Junior, VS Bolzani, M Furlan, CAM Fraga, EJ Barreiro Química Nova 27, 655-660, 2004 | 178 | 2004 |
| Design, Synthesis, and Pharmacological Profile of Novel Fused Pyrazolo[4,3-d]pyridine and Pyrazolo[3,4-b][1,8]naphthyridine Isosteres: A New Class of Potent … EJ Barreiro, CA Camara, H Verli, L Brazil-Más, NG Castro, WM Cintra, ... Journal of medicinal chemistry 46 (7), 1144-1152, 2003 | 145 | 2003 |
| Synthesis and vasodilatory activity of new N-acylhydrazone derivatives, designed as LASSBio-294 analogues AG Silva, G Zapata-Sudo, AE Kummerle, CAM Fraga, EJ Barreiro, ... Bioorganic & medicinal chemistry 13 (10), 3431-3437, 2005 | 142 | 2005 |
| Medicinal chemistry of N-acylhydrazones: new lead-compounds of analgesic, antiinflammatory and antithrombotic drugs CAM Fraga, EJ Barreiro Current medicinal chemistry 13 (2), 167-198, 2006 | 134 | 2006 |
| The role of natural products in the discovery of new drug candidates for the treatment of neurodegenerative disorders II: Alzheimer's disease M Divino da Rocha, F Pereira Dias Viegas, H Cristina Campos, ... CNS & Neurological Disorders-Drug Targets-CNS & Neurological Disorders) 10 …, 2011 | 133 | 2011 |
| Design, Synthesis, and Pharmacological Evaluation of Novel N-Acylhydrazone Derivatives as Potent Histone Deacetylase 6/8 Dual Inhibitors DA Rodrigues, GÀ Ferreira-Silva, ACS Ferreira, RA Fernandes, JK Kwee, ... Journal of medicinal chemistry 59 (2), 655-670, 2016 | 126 | 2016 |
| Design, Synthesis, and Pharmacological Evaluation of N-Acylhydrazones and Novel Conformationally Constrained Compounds as Selective and Potent Orally … AE Kümmerle, M Schmitt, SVS Cardozo, C Lugnier, P Villa, AB Lopes, ... Journal of medicinal chemistry 55 (17), 7525-7545, 2012 | 121 | 2012 |
| Characterization of Amide Bond Conformers for a Novel Heterocyclic Template of N-acylhydrazone Derivatives AB Lopes, E Miguez, AE Kümmerle, VM Rumjanek, CAM Fraga, ... Molecules 18 (10), 11683-11704, 2013 | 117 | 2013 |
| Synthesis and antitrypanosomal profile of new functionalized 1, 3, 4-thiadiazole-2-arylhydrazone derivatives, designed as non-mutagenic megazol analogues SA Carvalho, EF da Silva, RM Santa-Rita, SL de Castro, CAM Fraga Bioorganic & medicinal chemistry letters 14 (24), 5967-5970, 2004 | 111 | 2004 |
| Design, synthesis and pharmacological profile of novel dopamine D2 receptor ligands R Menegatti, AC Cunha, VF Ferreira, EFR Perreira, A El-Nabawi, ... Bioorganic & medicinal chemistry 11 (22), 4807-4813, 2003 | 110 | 2003 |
| Design and synthesis of 3, 4-methylenedioxy-6-nitrophenoxyacetylhydrazone derivatives obtained from natural safrole: new lead-agents with analgesic and antipyretic properties HJC Bezerra-Netto, DI Lacerda, ALP Miranda, HM Alves, EJ Barreiro, ... Bioorganic & medicinal chemistry 14 (23), 7924-7935, 2006 | 108 | 2006 |
| Design, synthesis and antiinflammatory activity of novel phthalimide derivatives, structurally related to thalidomide AL Machado, LM Lima, JX Araújo-Jr, CAM Fraga, VLG Koatz, EJ Barreiro Bioorganic & Medicinal Chemistry Letters 15 (4), 1169-1172, 2005 | 105 | 2005 |
Eliezer J. BarreiroProfessor de Química Medicinal, Universidade Federal do Rio de JaneiroVerified email at ccsdecania.ufrj.br
