Natural products in drug discovery: advances and opportunities AG Atanasov, SB Zotchev, VM Dirsch, CT Supuran Nature reviews Drug discovery 20 (3), 200-216, 2021 | 3431 | 2021 |
Minimum information about a biosynthetic gene cluster MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ... Nature chemical biology 11 (9), 625-631, 2015 | 914 | 2015 |
Bacterial metabolism of long-chain n-alkanes A Wentzel, TE Ellingsen, HK Kotlar, SB Zotchev, M Throne-Holst Applied microbiology and biotechnology 76, 1209-1221, 2007 | 561 | 2007 |
Identification of Novel Genes Involved in Long-Chain n-Alkane Degradation by Acinetobacter sp. Strain DSM 17874 M Throne-Holst, A Wentzel, TE Ellingsen, HK Kotlar, SB Zotchev Applied and environmental microbiology 73 (10), 3327-3332, 2007 | 348 | 2007 |
Polyene macrolide antibiotics and their applications in human therapy SB Zotchev Current medicinal chemistry 10 (3), 211-223, 2003 | 342 | 2003 |
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway T Brautaset, ON Sekurova, H Sletta, TE Ellingsen, AR Strøm, S Valla, ... Chemistry & biology 7 (6), 395-403, 2000 | 334 | 2000 |
Actinomycetes from sediments in the Trondheim fjord, Norway: diversity and biological activity H Bredholt, E Fjærvik, G Johnsen, SB Zotchev Marine drugs 6 (1), 12-24, 2008 | 302 | 2008 |
Rare actinomycete bacteria from the shallow water sediments of the Trondheim fjord, Norway: isolation, diversity and biological activity H Bredholdt, OA Galatenko, K Engelhardt, E Fjærvik, LP Terekhova, ... Environmental microbiology 9 (11), 2756-2764, 2007 | 268 | 2007 |
Marine actinomycetes as an emerging resource for the drug development pipelines SB Zotchev Journal of biotechnology 158 (4), 168-175, 2012 | 233 | 2012 |
Production of a New Thiopeptide Antibiotic, TP-1161, by a Marine Nocardiopsis Species K Engelhardt, KF Degnes, M Kemmler, H Bredholt, E Fjærvik, ... Applied and environmental microbiology 76 (15), 4969-4976, 2010 | 224 | 2010 |
Polyene antibiotic biosynthesis gene clusters JF Aparicio, P Caffrey, JA Gil, SB Zotchev Applied microbiology and biotechnology 61, 179-188, 2003 | 192 | 2003 |
International natural product sciences taskforce AG Atanasov, SB Zotchev, VM Dirsch, CT Supuran Nat. Rev. Drug Discov 20 (3), 200-216, 2021 | 178 | 2021 |
Novel bioactive natural products from bacteria via bioprospecting, genome mining and metabolic engineering ON Sekurova, O Schneider, SB Zotchev Microbial biotechnology 12 (5), 828-844, 2019 | 149 | 2019 |
In Vivo Analysis of the Regulatory Genes in the Nystatin Biosynthetic Gene Cluster of Streptomyces noursei ATCC 11455 Reveals Their Differential Control Over … ON Sekurova, T Brautaset, H Sletta, SEF Borgos, ØM Jakobsen, ... Journal of bacteriology 186 (5), 1345-1354, 2004 | 142 | 2004 |
Production of bioactive plant secondary metabolites through in vitro technologies—status and outlook C Wawrosch, SB Zotchev Applied Microbiology and Biotechnology 105 (18), 6649-6668, 2021 | 141 | 2021 |
New natural products identified by combined genomics-metabolomics profiling of marine Streptomyces sp. MP131-18 C Paulus, Y Rebets, B Tokovenko, S Nadmid, LP Terekhova, ... Scientific Reports 7 (1), 42382, 2017 | 115 | 2017 |
Violacein-Producing Collimonas sp. from the Sea Surface Microlayer of Costal Waters in Trøndelag, Norway S Hakvåg, E Fjærvik, G Klinkenberg, SEF Borgos, KD Josefsen, ... Marine drugs 7 (4), 576-588, 2009 | 115 | 2009 |
Biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei E Fjærvik, SB Zotchev Applied microbiology and biotechnology 67, 436-443, 2005 | 109 | 2005 |
Biosynthetic engineering of polyene macrolides towards generation of improved antifungal and antiparasitic agents P Caffrey, JF Aparicio, F Malpartida, SB Zotchev Current topics in medicinal chemistry 8 (8), 639-653, 2008 | 105 | 2008 |
Improved antifungal polyene macrolides via engineering of the nystatin biosynthetic genes in Streptomyces noursei T Brautaset, H Sletta, A Nedal, SEF Borgos, KF Degnes, I Bakke, ... Chemistry & biology 15 (11), 1198-1206, 2008 | 103 | 2008 |