| The emerging role and targetability of the TCA cycle in cancer metabolism NM Anderson, P Mucka, JG Kern, H Feng Protein & cell 9 (2), 216-237, 2018 | 494 | 2018 |
| Activated ALK collaborates with MYCN in neuroblastoma pathogenesis S Zhu, JS Lee, F Guo, J Shin, AR Perez-Atayde, JL Kutok, SJ Rodig, ... Cancer cell 21 (3), 362-373, 2012 | 426 | 2012 |
| CUL-4 ubiquitin ligase maintains genome stability by restraining DNA-replication licensing W Zhong, H Feng, FE Santiago, ET Kipreos Nature 423 (6942), 885-889, 2003 | 376 | 2003 |
| Cre/lox-regulated transgenic zebrafish model with conditional myc-induced T cell acute lymphoblastic leukemia DM Langenau, H Feng, S Berghmans, JP Kanki, JL Kutok, AT Look Proceedings of the National Academy of Sciences 102 (17), 6068-6073, 2005 | 319 | 2005 |
| T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation H Feng, DL Stachura, RM White, A Gutierrez, L Zhang, T Sanda, CA Jette, ... Cancer cell 18 (4), 353-366, 2010 | 181 | 2010 |
| CUL-2 is required for the G1-to-S-phase transition and mitotic chromosome condensation in Caenorhabditis elegans H Feng, W Zhong, G Punkosdy, S Gu, L Zhou, EK Seabolt, ET Kipreos Nature cell biology 1 (8), 486-492, 1999 | 168 | 1999 |
| Heat‐shock induction of T‐cell lymphoma/leukaemia in conditional Cre/lox‐regulated transgenic zebrafish H Feng, DM Langenau, JA Madge, A Quinkertz, A Gutierrez, DS Neuberg, ... British journal of haematology 138 (2), 169-175, 2007 | 150 | 2007 |
| Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia A Gutierrez, R Grebliunaite, H Feng, E Kozakewich, S Zhu, F Guo, ... Journal of Experimental Medicine 208 (8), 1595-1603, 2011 | 137 | 2011 |
| Direct phosphorylation and stabilization of MYC by Aurora B kinase promote T-cell leukemogenesis J Jiang, J Wang, M Yue, X Cai, T Wang, C Wu, H Su, Y Wang, M Han, ... Cancer Cell 37 (2), 200-215. e5, 2020 | 100 | 2020 |
| Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency JS Blackburn, S Liu, DM Raiser, SA Martinez, H Feng, ND Meeker, ... Leukemia 26 (9), 2069-2078, 2012 | 89 | 2012 |
| Towards Resolving the Pro-and Anti-Tumor Effects of the Aryl Hydrocarbon Receptor S Narasimhan, E Stanford Zulick, O Novikov, AJ Parks, JJ Schlezinger, ... International journal of molecular sciences 19 (5), 1388, 2018 | 64 | 2018 |
| Hypoxia-induced expression of phosducin-like 3 regulates expression of VEGFR-2 and promotes angiogenesis S Srinivasan, V Chitalia, RD Meyer, E Hartsough, M Mehta, I Harrold, ... Angiogenesis 18 (4), 449-462, 2015 | 61 | 2015 |
| The TCA cycle transferase DLST is important for MYC-mediated leukemogenesis NM Anderson, D Li, HL Peng, FJF Laroche, MR Mansour, E Gjini, M Aioub, ... Leukemia 30 (6), 1365-1374, 2016 | 58 | 2016 |
| BCL2-specific inhibitor ABT-199 synergizes strongly with cytarabine against the early immature LOUCY cell line but not more-differentiated T-ALL cell lines NM Anderson, I Harrold, MR Mansour, T Sanda, M McKeown, N Nagykary, ... Leukemia 28 (5), 1145-1148, 2014 | 58 | 2014 |
| C. elegans CUL-4 Prevents Rereplication by Promoting the Nuclear Export of CDC-6 via a CKI-1-Dependent Pathway J Kim, H Feng, ET Kipreos Current biology 17 (11), 966-972, 2007 | 58 | 2007 |
| Functional and genomic analyses reveal therapeutic potential of targeting β-catenin/CBP activity in head and neck cancer VK Kartha, KA Alamoud, K Sadykov, BC Nguyen, F Laroche, H Feng, ... Genome medicine 10 (1), 1-18, 2018 | 52 | 2018 |
| The c-Cbl ubiquitin ligase regulates nuclear β-catenin and angiogenesis by its tyrosine phosphorylation mediated through the Wnt signaling pathway S Shivanna, I Harrold, M Shashar, R Meyer, C Kiang, J Francis, Q Zhao, ... Journal of Biological Chemistry 290 (20), 12537-12546, 2015 | 51 | 2015 |
| C. elegans CAND-1 regulates cullin neddylation, cell proliferation and morphogenesis in specific tissues DR Bosu, H Feng, K Min, Y Kim, MR Wallenfang, ET Kipreos Developmental biology 346 (1), 113-126, 2010 | 49 | 2010 |
| Zebrafish B Cell Development without a Pre–B Cell Stage, Revealed by CD79 Fluorescence Reporter Transgenes X Liu, YS Li, SA Shinton, J Rhodes, L Tang, H Feng, CA Jette, AT Look, ... The Journal of Immunology 199 (5), 1706-1715, 2017 | 45 | 2017 |
| Metabolic enzyme DLST promotes tumor aggression and reveals a vulnerability to OXPHOS inhibition in high-risk neuroblastoma NM Anderson, X Qin, JM Finan, A Lam, J Athoe, R Missiaen, N Skuli, ... Cancer research 81 (17), 4417-4430, 2021 | 44 | 2021 |
Thomas LookProfessor of Pediatrics, Harvard Medical SchoolVerified email at dfci.harvard.edu