| Human iPSC-derived blood-brain barrier chips enable disease modeling and personalized medicine applications GD Vatine, R Barrile, MJ Workman, S Sances, BK Barriga, M Rahnama, ... Cell stem cell 24 (6), 995-1005. e6, 2019 | 514 | 2019 |
| Reproducing human and cross-species drug toxicities using a Liver-Chip KJ Jang, MA Otieno, J Ronxhi, HK Lim, L Ewart, KR Kodella, ... Science translational medicine 11 (517), eaax5516, 2019 | 385 | 2019 |
| Primary human lung alveolus‐on‐a‐chip model of intravascular thrombosis for assessment of therapeutics A Jain, R Barrile, AD van der Meer, A Mammoto, T Mammoto, ... Clinical pharmacology & therapeutics 103 (2), 332-340, 2018 | 319 | 2018 |
| Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium A Jain, AD van der Meer, AL Papa, R Barrile, A Lai, BL Schlechter, ... Biomedical microdevices 18, 1-7, 2016 | 148 | 2016 |
| Organ‐on‐chip recapitulates thrombosis induced by an anti‐CD154 monoclonal antibody: translational potential of advanced microengineered systems R Barrile, AD van der Meer, H Park, JP Fraser, D Simic, F Teng, ... Clinical pharmacology & therapeutics 104 (6), 1240-1248, 2018 | 125 | 2018 |
| A lung-on-chip model of early Mycobacterium tuberculosis infection reveals an essential role for alveolar epithelial cells in controlling bacterial growth VV Thacker, N Dhar, K Sharma, R Barrile, K Karalis, JD McKinney Elife 9, e59961, 2020 | 114 | 2020 |
| Stem cell-based Lung-on-Chips: The best of both worlds? JC Nawroth, R Barrile, D Conegliano, S van Riet, PS Hiemstra, ... Advanced drug delivery reviews 140, 12-32, 2019 | 86 | 2019 |
| A novel organ-chip system emulates three-dimensional architecture of the human epithelia and the mechanical forces acting on it A Varone, JK Nguyen, L Leng, R Barrile, J Sliz, C Lucchesi, N Wen, ... Biomaterials 275, 120957, 2021 | 62 | 2021 |
| Human immunocompetent Organ-on-Chip platforms allow safety profiling of tumor-targeted T-cell bispecific antibodies SJ Kerns, C Belgur, D Petropolis, M Kanellias, R Barrile, J Sam, ... Elife 10, e67106, 2021 | 57 | 2021 |
| Clostridium difficile Toxins Facilitate Bacterial Colonization by Modulating the Fence and Gate Function of Colonic Epithelium M Kasendra, R Barrile, R Leuzzi, M Soriani The Journal of infectious diseases 209 (7), 1095-1104, 2014 | 47 | 2014 |
| Human heat shock protein (Hsp) 90 interferes with Neisseria meningitidis adhesin A (NadA)‐mediated adhesion and invasion P Montanari, G Bozza, B Capecchi, E Caproni, R Barrile, N Norais, ... Cellular microbiology 14 (3), 368-385, 2012 | 40 | 2012 |
| Neisseria meningitidis subverts the polarized organization and intracellular trafficking of host cells to cross the epithelial barrier R Barrile, M Kasendra, S Rossi‐Paccani, M Merola, M Pizza, C Baldari, ... Cellular microbiology 17 (9), 1365-1375, 2015 | 32 | 2015 |
| The C2 fragment from Neisseria meningitidis antigen NHBA increases endothelial permeability by destabilizing adherens junctions A Casellato, S Rossi Paccani, R Barrile, F Bossi, L Ciucchi, G Codolo, ... Cellular microbiology 16 (6), 925-937, 2014 | 30 | 2014 |
| Modelling human physiology on-chip: historical perspectives and future directions S Pun, LC Haney, R Barrile Micromachines 12 (10), 1250, 2021 | 22 | 2021 |
| Role of ARF6, Rab11 and External Hsp90 in the Trafficking and Recycling of Recombinant-Soluble N eisseria meningitidis Ad hesin A (rNadA) in Human Epithelial Cells G Bozza, M Capitani, P Montanari, B Benucci, M Biancucci, V Nardi-Dei, ... PLoS One 9 (10), e110047, 2014 | 22 | 2014 |
| Liver-Chip: Reproducing human and cross-species toxicities KJ Jang, MA Otieno, J Ronxhi, HK Lim, L Ewart, K Kodella, D Petropolis, ... BioRxiv, 631002, 2019 | 14 | 2019 |
| A lung-on-chip infection model reveals protective and permissive roles of alveolar epithelial cells in tuberculosis VV Thacker, N Dhar, K Sharma, R Barrile, K Karalis, JD McKinney bioRxiv, 2020.02. 03.931170, 2020 | 8 | 2020 |
| Additive channels D Levner, CD Hinojosa, N Wen, J Fraser, J Nguyen, R Barrile, G Hamilton, ... US Patent App. 15/648,049, 2018 | 8 | 2018 |
| In vitro epithelial models comprising lamina propria-derived cells SJ Kerns, R Barrile, G Hamilton, C Karalis, D Levner, C Lucchesi, ... US Patent 10,828,638, 2020 | 6 | 2020 |
| Basic models to advanced systems: harnessing the power of organoids-based microphysiological models of the human brain K Boylin, GV Aquino, M Purdon, K Abedi, M Kasendra, R Barrile Biofabrication 16 (3), 032007, 2024 | 5 | 2024 |
