| Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice NF Fitz, A Cronican, T Pham, A Fogg, AH Fauq, R Chapman, I Lefterov, ... Journal of Neuroscience 30 (20), 6862-6872, 2010 | 206 | 2010 |
| The role of APOE and TREM2 in Alzheimer′ s disease—current understanding and perspectives CM Wolfe, NF Fitz, KN Nam, I Lefterov, R Koldamova International journal of molecular sciences 20 (1), 81, 2018 | 183 | 2018 |
| Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice NF Fitz, AA Cronican, M Saleem, AH Fauq, R Chapman, I Lefterov, ... Journal of Neuroscience 32 (38), 13125-13136, 2012 | 159 | 2012 |
| ATP-binding cassette transporter A1: from metabolism to neurodegeneration R Koldamova, NF Fitz, I Lefterov Neurobiology of disease 72, 13-21, 2014 | 150 | 2014 |
| Apolipoprotein AI deficiency increases cerebral amyloid angiopathy and cognitive deficits in APP/PS1ΔE9 mice I Lefterov, NF Fitz, AA Cronican, A Fogg, P Lefterov, R Kodali, R Wetzel, ... Journal of Biological Chemistry 285 (47), 36945-36957, 2010 | 144 | 2010 |
| The role of ATP-binding cassette transporter A1 in Alzheimer's disease and neurodegeneration R Koldamova, NF Fitz, I Lefterov Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2010 | 120 | 2010 |
| Genome-wide alteration of histone H3K9 acetylation pattern in mouse offspring prenatally exposed to arsenic AA Cronican, NF Fitz, A Carter, M Saleem, S Shiva, A Barchowsky, ... PloS one 8 (2), e53478, 2013 | 102 | 2013 |
| Phospholipids of APOE lipoproteins activate microglia in an isoform-specific manner in preclinical models of Alzheimer’s disease NF Fitz, KN Nam, CM Wolfe, F Letronne, BE Playso, BE Iordanova, ... Nature communications 12 (1), 3416, 2021 | 92 | 2021 |
| Effect of high fat diet on phenotype, brain transcriptome and lipidome in Alzheimer’s model mice KN Nam, A Mounier, CM Wolfe, NF Fitz, AY Carter, EL Castranio, ... Scientific reports 7 (1), 4307, 2017 | 92 | 2017 |
| Regulation of aged skeletal muscle regeneration by circulating extracellular vesicles A Sahu, ZJ Clemens, SN Shinde, S Sivakumar, A Pius, A Bhatia, ... Nature aging 1 (12), 1148-1161, 2021 | 89 | 2021 |
| Genome-wide approaches reveal EGR1-controlled regulatory networks associated with neurodegeneration R Koldamova, J Schug, M Lefterova, AA Cronican, NF Fitz, FA Davenport, ... Neurobiology of disease 63, 107-114, 2014 | 85 | 2014 |
| Bexarotene-activated retinoid X receptors regulate neuronal differentiation and dendritic complexity A Mounier, D Georgiev, KN Nam, NF Fitz, EL Castranio, CM Wolfe, ... Journal of Neuroscience 35 (34), 11862-11876, 2015 | 74 | 2015 |
| Memory Deficits in APP23/Abca1+/− Mice Correlate with the Level of Aβ Oligomers I Lefterov, NF Fitz, A Cronican, P Lefterov, M Staufenbiel, R Koldamova ASN neuro 1 (2), AN20090015, 2009 | 74 | 2009 |
| Trem2 deficiency differentially affects phenotype and transcriptome of human APOE3 and APOE4 mice NF Fitz, CM Wolfe, BE Playso, RJ Biedrzycki, Y Lu, KN Nam, I Lefterov, ... Molecular Neurodegeneration 15, 1-21, 2020 | 61 | 2020 |
| APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain I Lefterov, CM Wolfe, NF Fitz, KN Nam, F Letronne, RJ Biedrzycki, J Kofler, ... Alzheimer's research & therapy 11, 1-16, 2019 | 60 | 2019 |
| Microtubules modulate melatonin receptors involved in phase‐shifting circadian activity rhythms: in vitro and in vivo evidence MJ Jarzynka, DK Passey, DA Johnson, NV Konduru, NF Fitz, NM Radio, ... Journal of pineal research 46 (2), 161-171, 2009 | 58 | 2009 |
| Selective lesion of septal cholinergic neurons in rats impairs acquisition of a delayed matching to position T-maze task by delaying the shift from a response to a place strategy NF Fitz, RB Gibbs, DA Johnson Brain research bulletin 77 (6), 356-360, 2008 | 54 | 2008 |
| Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury EL Castranio, A Mounier, CM Wolfe, KN Nam, NF Fitz, F Letronne, ... Neurobiology of disease 105, 1-14, 2017 | 48 | 2017 |
| Proton pump inhibitor lansoprazole is a nuclear liver X receptor agonist AA Cronican, NF Fitz, T Pham, A Fogg, B Kifer, R Koldamova, I Lefterov Biochemical pharmacology 79 (9), 1310-1316, 2010 | 43 | 2010 |
| RXR controlled regulatory networks identified in mouse brain counteract deleterious effects of Aβ oligomers KN Nam, A Mounier, NF Fitz, C Wolfe, J Schug, I Lefterov, R Koldamova Scientific reports 6 (1), 24048, 2016 | 42 | 2016 |
