| Integrative analysis of 111 reference human epigenomes A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, A Heravi-Moussavi, ... Nature 518 (7539), 317-330, 2015 | 6312 | 2015 |
| Driving fast-spiking cells induces gamma rhythm and controls sensory responses JA Cardin, M Carlén, K Meletis, U Knoblich, F Zhang, K Deisseroth, ... Nature 459 (7247), 663-667, 2009 | 2931 | 2009 |
| Single-cell transcriptomic analysis of Alzheimer’s disease H Mathys, J Davila-Velderrain, Z Peng, F Gao, S Mohammadi, JZ Young, ... Nature 570 (7761), 332-337, 2019 | 1981 | 2019 |
| Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration GN Patrick, L Zukerberg, M Nikolic, S de La Monte, P Dikkes, LH Tsai Nature 402 (6762), 615-622, 1999 | 1934 | 1999 |
| A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27Kip1-deficient mice ML Fero, M Rivkin, M Tasch, P Porter, CE Carow, E Firpo, K Polyak, ... Cell 85 (5), 733-744, 1996 | 1827 | 1996 |
| HDAC2 negatively regulates memory formation and synaptic plasticity JS Guan, SJ Haggarty, E Giacometti, JH Dannenberg, N Joseph, J Gao, ... Nature 459 (7243), 55-60, 2009 | 1810 | 2009 |
| Recovery of learning and memory is associated with chromatin remodelling A Fischer, F Sananbenesi, X Wang, M Dobbin, LH Tsai Nature 447 (7141), 178-182, 2007 | 1462 | 2007 |
| Inhibition of cyclin-dependent kinases by p21. JW Harper, SJ Elledge, K Keyomarsi, B Dynlacht, LH Tsai, P Zhang, ... Molecular biology of the cell 6 (4), 387-400, 1995 | 1400 | 1995 |
| A decade of CDK5 R Dhavan, LH Tsai Nature reviews Molecular cell biology 2 (10), 749-759, 2001 | 1398 | 2001 |
| Neurotoxicity induces cleavage of p35 to p25 by calpain M Lee, YT Kwon, M Li, J Peng, RM Friedlander, LH Tsai Nature 405 (6784), 360-364, 2000 | 1330 | 2000 |
| SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis D Kim, MD Nguyen, MM Dobbin, A Fischer, F Sananbenesi, JT Rodgers, ... The EMBO journal 26 (13), 3169-3179, 2007 | 1290 | 2007 |
| Gamma frequency entrainment attenuates amyloid load and modifies microglia HF Iaccarino, AC Singer, AJ Martorell, A Rudenko, F Gao, TZ Gillingham, ... Nature 540 (7632), 230-235, 2016 | 1187 | 2016 |
| A family of human cdc2‐related protein kinases. M Meyerson, GH Enders, CL Wu, LK Su, C Gorka, C Nelson, E Harlow, ... The EMBO journal 11 (8), 2909-2917, 1992 | 1182 | 1992 |
| p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5 LH Tsai, I Delalle, VS Caviness Jr, T Chae, E Harlow Nature 371 (6496), 419-423, 1994 | 1130 | 1994 |
| A novel pathway regulates memory and plasticity via SIRT1 and miR-134 J Gao, WY Wang, YW Mao, J Gräff, JS Guan, L Pan, G Mak, D Kim, SC Su, ... Nature 466 (7310), 1105-1109, 2010 | 1108 | 2010 |
| APOE4 causes widespread molecular and cellular alterations associated with Alzheimer’s disease phenotypes in human iPSC-derived brain cell types YT Lin, J Seo, F Gao, HM Feldman, HL Wen, J Penney, HP Cam, ... Neuron 98 (6), 1141-1154. e7, 2018 | 1014 | 2018 |
| An epigenetic blockade of cognitive functions in the neurodegenerating brain J Gräff, D Rei, JS Guan, WY Wang, J Seo, KM Hennig, TJF Nieland, ... Nature 483 (7388), 222-226, 2012 | 928 | 2012 |
| Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3β/β-catenin signaling Y Mao, X Ge, CL Frank, JM Madison, AN Koehler, MK Doud, C Tassa, ... Cell 136 (6), 1017-1031, 2009 | 921 | 2009 |
| Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality T Chae, YT Kwon, R Bronson, P Dikkes, E Li, LH Tsai Neuron 18 (1), 29-42, 1997 | 919 | 1997 |
| Microglia states and nomenclature: A field at its crossroads RC Paolicelli, A Sierra, B Stevens, ME Tremblay, A Aguzzi, B Ajami, I Amit, ... Neuron 110 (21), 3458-3483, 2022 | 912 | 2022 |
