Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo FJ Najm, M Madhavan, A Zaremba, E Shick, RT Karl, DC Factor, TE Miller, ... Nature 522 (7555), 216-220, 2015 | 443 | 2015 |
Cutting Edge: Anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+ CD25+ T regulatory cells AP Kohm, JS McMahon, JR Podojil, WS Begolka, M DeGutes, ... The Journal of Immunology 176 (6), 3301-3305, 2006 | 439 | 2006 |
Antigen-specific tolerance strategies for the prevention and treatment of autoimmune disease SD Miller, DM Turley, JR Podojil Nature Reviews Immunology 7 (9), 665-677, 2007 | 353 | 2007 |
Oligodendrocyte death results in immune-mediated CNS demyelination M Traka, JR Podojil, DP McCarthy, SD Miller, B Popko Nature neuroscience 19 (1), 65-74, 2016 | 209 | 2016 |
Molecular mechanisms of T‐cell receptor and costimulatory molecule ligation/blockade in autoimmune disease therapy JR Podojil, SD Miller Immunological reviews 229 (1), 337-355, 2009 | 168 | 2009 |
Potential targeting of B7‐H4 for the treatment of cancer JR Podojil, SD Miller Immunological reviews 276 (1), 40-51, 2017 | 153 | 2017 |
TAK-101 nanoparticles induce gluten-specific tolerance in celiac disease: a randomized, double-blind, placebo-controlled study CP Kelly, JA Murray, DA Leffler, DR Getts, AC Bledsoe, G Smithson, ... Gastroenterology 161 (1), 66-80. e8, 2021 | 126 | 2021 |
Gliadin nanoparticles induce immune tolerance to gliadin in mouse models of celiac disease TL Freitag, JR Podojil, RM Pearson, FJ Fokta, C Sahl, M Messing, ... Gastroenterology 158 (6), 1667-1681. e12, 2020 | 125 | 2020 |
A genetic mouse model of adult-onset, pervasive central nervous system demyelination with robust remyelination M Traka, K Arasi, RL Avila, JR Podojil, A Christakos, SD Miller, B Soliven, ... Brain 133 (10), 3017-3029, 2010 | 124 | 2010 |
Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic SW Way, JR Podojil, BL Clayton, A Zaremba, TL Collins, RB Kunjamma, ... Nature communications 6 (1), 6532, 2015 | 120 | 2015 |
Peripherally derived T regulatory and γδ T cells have opposing roles in the pathogenesis of intractable pediatric epilepsy D Xu, AP Robinson, T Ishii, DAS Duncan, TD Alden, GE Goings, I Ifergan, ... Journal of Experimental Medicine 215 (4), 1169-1186, 2018 | 115 | 2018 |
APOBEC-mediated mutagenesis in urothelial carcinoma is associated with improved survival, mutations in DNA damage response genes, and immune response AP Glaser, D Fantini, Y Wang, Y Yu, KJ Rimar, JR Podojil, SD Miller, ... Oncotarget 9 (4), 4537, 2018 | 114 | 2018 |
Tolerogenic Ag-PLG nanoparticles induce tregs to suppress activated diabetogenic CD4 and CD8 T cells S Prasad, T Neef, D Xu, JR Podojil, DR Getts, LD Shea, SD Miller Journal of autoimmunity 89, 112-124, 2018 | 109 | 2018 |
Selective regulation of mature IgG1 transcription by CD86 and β2-adrenergic receptor stimulation JR Podojil, VM Sanders The Journal of Immunology 170 (10), 5143-5151, 2003 | 98 | 2003 |
CD86 and β2-adrenergic receptor signaling pathways, respectively, increase Oct-2 and OCA-B expression and binding to the 3′-IgH enhancer in B cells JR Podojil, NW Kin, VM Sanders Journal of Biological Chemistry 279 (22), 23394-23404, 2004 | 86 | 2004 |
Pre-clinical and clinical implications of “inside-out” vs.“outside-in” paradigms in multiple sclerosis etiopathogenesis HE Titus, Y Chen, JR Podojil, AP Robinson, R Balabanov, B Popko, ... Frontiers in cellular neuroscience 14, 599717, 2020 | 85 | 2020 |
Targeting the B7 family of co-stimulatory molecules: successes and challenges JR Podojil, SD Miller BioDrugs 27, 1-13, 2013 | 83 | 2013 |
Advanced age increases immunosuppression in the brain and decreases immunotherapeutic efficacy in subjects with glioblastoma E Ladomersky, L Zhai, KL Lauing, A Bell, J Xu, M Kocherginsky, B Zhang, ... Clinical Cancer Research 26 (19), 5232-5245, 2020 | 82 | 2020 |
B7-H4Ig inhibits mouse and human T-cell function and treats EAE via IL-10/Treg-dependent mechanisms JR Podojil, LN Liu, SA Marshall, MY Chiang, GE Goings, L Chen, ... Journal of autoimmunity 44, 71-81, 2013 | 81 | 2013 |
Overcoming challenges in treating autoimmuntity: development of tolerogenic immune-modifying nanoparticles RM Pearson, JR Podojil, LD Shea, NJC King, SD Miller, DR Getts Nanomedicine: Nanotechnology, Biology and Medicine 18, 282-291, 2019 | 80 | 2019 |