| Antidepressant drugs act by directly binding to TRKB neurotrophin receptors PC Casarotto, M Girych, SM Fred, V Kovaleva, R Moliner, G Enkavi, ... Cell 184 (5), 1299-1313. e19, 2021 | 506 | 2021 |
| Psychedelics promote plasticity by directly binding to BDNF receptor TrkB R Moliner, M Girych, CA Brunello, V Kovaleva, C Biojone, G Enkavi, ... Nature Neuroscience 26 (6), 1032-1041, 2023 | 210 | 2023 |
| Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors PC Casarotto, FV Gomes, LBM Resstel, FS Guimarães Behavioural pharmacology 21 (4), 353-358, 2010 | 161 | 2010 |
| Opposing roles for cannabinoid receptor type-1 (CB1) and transient receptor potential vanilloid type-1 channel (TRPV1) on the modulation of panic-like responses in rats PC Casarotto, ALB Terzian, DC Aguiar, H Zangrossi, FS Guimaraes, ... Neuropsychopharmacology 37 (2), 478-486, 2012 | 133 | 2012 |
| Repeated paroxetine treatment reverses anhedonia induced in rats by chronic mild stress or dexamethasone PC Casarotto, R Andreatini European Neuropsychopharmacology 17 (11), 735-742, 2007 | 118 | 2007 |
| Isoflurane produces antidepressant effects and induces TrkB signaling in rodents H Antila, M Ryazantseva, D Popova, P Sipilä, R Guirado, S Kohtala, ... Scientific reports 7 (1), 7811, 2017 | 89 | 2017 |
| Facilitation of CB1 receptor-mediated neurotransmission decreases marble burying behavior in mice FV Gomes, PC Casarotto, LBM Resstel, FS Guimarães Progress in Neuro-Psychopharmacology and Biological Psychiatry 35 (2), 434-438, 2011 | 79 | 2011 |
| Cannabidiol reverses the mCPP‐induced increase in marble‐burying behavior M Nardo, PC Casarotto, FV Gomes, FS Guimaraes Fundamental & clinical pharmacology 28 (5), 544-550, 2014 | 77 | 2014 |
| Antidepressant-and anticompulsive-like effects of purinergic receptor blockade: involvement of nitric oxide VS Pereira, PC Casarotto, VA Hiroaki-Sato, AG Sartim, FS Guimarães, ... European Neuropsychopharmacology 23 (12), 1769-1778, 2013 | 67 | 2013 |
| Interplay between nitric oxide and brain-derived neurotrophic factor in neuronal plasticity C Biojone, P Cabrera Casarotto, S Regiane Joca, E Castrén CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2015 | 62 | 2015 |
| Beyond good and evil: a putative continuum-sorting hypothesis for the functional role of proBDNF/BDNF-propeptide/mBDNF in antidepressant treatment CRAF Diniz, PC Casarotto, L Resstel, SRL Joca Neuroscience & Biobehavioral Reviews, 2018 | 57 | 2018 |
| Antidepressant and Antipsychotic Drugs Reduce Viral Infection by SARS-CoV-2 and Fluoxetine Shows Antiviral Activity Against the Novel Variants in vitro SM Fred, S Kuivanen, H Ugurlu, PC Casarotto, L Levanov, K Saksela, ... Frontiers in Pharmacology 12, 755600, 2022 | 56 | 2022 |
| Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2 SM Fred, L Laukkanen, CA Brunello, L Vesa, H Göös, I Cardon, R Moliner, ... Journal of Biological Chemistry 294 (48), 18150-18161, 2019 | 47 | 2019 |
| Chondroitinase and antidepressants promote plasticity by releasing TRKB from dephosphorylating control of PTPσ in parvalbumin neurons A Lesnikova, PC Casarotto, SM Fred, M Voipio, F Winkel, A Steinzeig, ... Journal of Neuroscience 41 (5), 972-980, 2021 | 46 | 2021 |
| Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN CRAF Diniz, PC Casarotto, SM Fred, C Biojone, E Castrén, SRL Joca Neuropharmacology 135, 163-171, 2018 | 45 | 2018 |
| Longitudinal two-photon imaging in somatosensory cortex of behaving mice reveals dendritic spine formation enhancement by subchronic administration of low-dose ketamine E Pryazhnikov, E Mugantseva, P Casarotto, J Kolikova, SM Fred, ... Scientific reports 8 (1), 6464, 2018 | 44 | 2018 |
| Panicolytic-like effect of BDNF in the rat dorsal periaqueductal grey matter: the role of 5-HT and GABA PC Casarotto, VC de Bortoli, FM de Aguiar Corrêa, LB Moraes Resstel, ... International Journal of Neuropsychopharmacology 13 (5), 573-582, 2010 | 37 | 2010 |
| Anti-aversive effects of the atypical antipsychotic, aripiprazole, in animal models of anxiety C Biojone, PC Casarotto, LB Resstel, H Zangrossi Jr, FS Guimaraes, ... Journal of psychopharmacology 25 (6), 801-807, 2011 | 35 | 2011 |
| Fine-tuning of defensive behaviors in the dorsal periaqueductal gray by atypical neurotransmitters MV Fogaça, SF Lisboa, DC Aguiar, FA Moreira, FV Gomes, PC Casarotto, ... Brazilian Journal of Medical and Biological Research 45, 357-365, 2012 | 34 | 2012 |
| BDNF receptor TrkB as the mediator of the antidepressant drug action P Casarotto, J Umemori, E Castrén Frontiers in Molecular Neuroscience 15, 1032224, 2022 | 30 | 2022 |
Eero CastrénNeuroscience Center, University of Helsinki, FinlandVerified email at helsinki.fi