| Comprehensive molecular portraits of human breast tumours Brigham & Women’s Hospital & Harvard Medical School Chin Lynda 9 11 Park ... Nature 490 (7418), 61-70, 2012 | 11457 | 2012 |
| Progesterone receptor modulates ERα action in breast cancer H Mohammed, IA Russell, R Stark, OM Rueda, TE Hickey, GA Tarulli, ... Nature 523 (7560), 313-317, 2015 | 790 | 2015 |
| An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer ML Gatza, GO Silva, JS Parker, C Fan, CM Perou Nature genetics 46 (10), 1051-1059, 2014 | 295 | 2014 |
| Comprehensive analysis of The Cancer Genome Atlas reveals a unique gene and non-coding RNA signature of fibrolamellar carcinoma TA Dinh, ECM Vitucci, E Wauthier, RP Graham, WA Pitman, T Oikawa, ... Scientific reports 7 (1), 44653, 2017 | 91 | 2017 |
| Loss of Heterozygosity at the CYP2D6 Locus in Breast Cancer: Implications for Germline Pharmacogenetic Studies MP Goetz, JX Sun, VJ Suman, GO Silva, CM Perou, Y Nakamura, NJ Cox, ... Journal of the National Cancer Institute 107 (2), dju401, 2015 | 71 | 2015 |
| Amplification of SOX4 promotes PI3K/Akt signaling in human breast cancer GA Mehta, JS Parker, GO Silva, KA Hoadley, CM Perou, ML Gatza Breast cancer research and treatment 162, 439-450, 2017 | 57 | 2017 |
| Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer GO Silva, X He, JS Parker, ML Gatza, LA Carey, JP Hou, SL Moulder, ... Breast cancer research and treatment 152, 347-356, 2015 | 51 | 2015 |
| Activating PIK3CA mutations induce an epidermal growth factor receptor (EGFR)/extracellular signal-regulated kinase (ERK) paracrine signaling axis in basal-like breast cancer CD Young, LJ Zimmerman, D Hoshino, L Formisano, AB Hanker, ... Molecular & cellular proteomics 14 (7), 1959-1976, 2015 | 45 | 2015 |
| A mouse model featuring tissue-specific deletion of p53 and Brca1 gives rise to mammary tumors with genomic and transcriptomic similarities to human basal-like breast cancer DP Hollern, CM Contreras, S Dance-Barnes, GO Silva, AD Pfefferle, ... Breast cancer research and treatment 174, 143-155, 2019 | 27 | 2019 |
| SynthEx: a synthetic-normal-based DNA sequencing tool for copy number alteration detection and tumor heterogeneity profiling GO Silva, MB Siegel, LE Mose, JS Parker, W Sun, CM Perou, M Chen Genome biology 18, 1-14, 2017 | 27 | 2017 |
| Characterization of copy number alterations in a mouse model of fibrosis‐associated hepatocellular carcinoma reveals concordance with human disease G Chappell, GO Silva, T Uehara, IP Pogribny, I Rusyn Cancer Medicine 5 (3), 574-585, 2016 | 8 | 2016 |
| Activating PIK3CA mutations induce an EGFR/ERK paracrine signaling axis in basal-like breast cancer CD Young, LJ Zimmerman, D Hoshino, L Formisano, AB Hanker, ... Mol Cell Proteomics 14, 1959-1976, 2015 | 7 | 2015 |
| MAP4K1 inhibition enhances immune cell activation and anti-tumor immunity in preclinical tumor models K Faia, A Toso, K Fetalvero, M Roche, S Bench, E O'Hearn, Q Cao, ... Cancer Research 81 (13_Supplement), 1717-1717, 2021 | 6 | 2021 |
| Development of a selective CDK2-E inhibitor in CCNE driven cancers YJ Choi, S Wenglowsky, V Brown, N Bifulco, YS Choi, J Guo, M Hatlen, ... Cancer research 81 (13_Supplement), 1279-1279, 2021 | 6 | 2021 |
| Evaluation of PRKACA as a therapeutic target for fibrolamellar carcinoma SS Schalm, E O’Hearn, K Wilson, TP LaBranche, G Silva, Z Zhang, ... bioRxiv, 2022.01. 31.477690, 2022 | 4 | 2022 |
| Evaluation of Protein Kinase cAMP-Activated Catalytic Subunit Alpha as a Therapeutic Target for Fibrolamellar Carcinoma SS Schalm, E O’Hearn, K Wilson, TP LaBranche, G Silva, Z Zhang, ... Gastro Hep Advances 2 (3), 307-321, 2023 | 3 | 2023 |
| combination therapy with MEK inhibition is efficacious in intracranial triple negative breast cancer models AED Van Swearingen, MB Siegel, MJ Sambade, S Sud, SM Miller, G Silva, ... Cancer Research 75 (15_Supplement), 2579-2579, 2015 | 1 | 2015 |
| Abstract B127: Evaluating PRKACA as a therapeutic target for Fibrolamellar Carcinoma SS Schalm, E O’Hearn, K Wilson, T LaBranche, G Silva, L DiPietro, ... Molecular Cancer Therapeutics 18 (12_Supplement), B127-B127, 2019 | | 2019 |
| Abstract S4-01: Identification of early versus late drivers of breast tumors and metastasis MB Siegel, X He, M Chen, JP Hou, AL Garrett, JB Dye, GO Silva, JE Usary, ... Cancer Research 76 (4_Supplement), S4-01-S4-01, 2016 | | 2016 |
| Targeted agents and chemotherapeutic treatments of genetically engineered Basal-like breast cancer mouse model CM Contreras, GO Silva, AD Pfefferle, CM Perou Cancer Research 75 (15_Supplement), 2307-2307, 2015 | | 2015 |