| Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding N Turner, GM Kowalski, SJ Leslie, S Risis, C Yang, RS Lee-Young, ... Diabetologia 56 (7), 1638-1648, 2013 | 482 | 2013 |
| BCAA catabolism in brown fat controls energy homeostasis through SLC25A44 T Yoneshiro, Q Wang, K Tajima, M Matsushita, H Maki, K Igarashi, Z Dai, ... Nature, 1-6, 2019 | 426 | 2019 |
| The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase PJ White, RW McGarrah, PA Grimsrud, SC Tso, WH Yang, JM Haldeman, ... Cell Metabolism, 2018 | 290 | 2018 |
| Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export Phillip J. White, Amanda L. Lapworth, Jie An, Liping Wang, Robert W ... Molecular Metabolism, 2016 | 279 | 2016 |
| Branched-chain amino acids in disease Are BCAAs a biomarker, causal agent, or both in cardiometabolic disease? PJ White, CB Newgard Science 363 (6427), 582-583, 2019 | 255 | 2019 |
| Insulin Reverses the High-Fat Diet–Induced Increase in Brain Aβ and Improves Memory in an Animal Model of Alzheimer Disease M Vandal, PJ White, C Tremblay, I St-Amour, G Chevrier, V Emond, ... Diabetes 63 (12), 4291-4301, 2014 | 253 | 2014 |
| Transgenic Restoration of Long-Chain n-3 Fatty Acids in Insulin Target Tissues Improves Resolution Capacity and Alleviates Obesity-Linked Inflammation and Insulin Resistance in … PJ White, M Arita, R Taguchi, JX Kang, A Marette Diabetes 59 (12), 3066-3073, 2010 | 237 | 2010 |
| Long-chain omega-3 fatty acids regulate bovine whole-body protein metabolism by promoting muscle insulin signalling to the Akt–mTOR–S6K1 pathway and insulin sensitivity AA Gingras, PJ White, PY Chouinard, P Julien, TA Davis, L Dombrowski, ... The Journal of physiology 579 (1), 269-284, 2007 | 237 | 2007 |
| Insulin action, type 2 diabetes, and branched-chain amino acids: a two-way street PJ White, RW McGarrah, MA Herman, JR Bain, SH Shah, CB Newgard Molecular Metabolism, 101261, 2021 | 211 | 2021 |
| Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression RE Ericksen, SL Lim, E McDonnell, WH Shuen, M Vadiveloo, PJ White, ... Cell Metabolism, 2019 | 205 | 2019 |
| Brain Insulin Lowers Circulating BCAA Levels by Inducing Hepatic BCAA Catabolism AC Shin, M Fasshauer, N Filatova, LA Grundell, E Zielinski, JY Zhou, ... Cell metabolism 20 (5), 898-909, 2014 | 167 | 2014 |
| Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans. KWE Glynn EL, Piner LW, Huffman KM, Slentz CA, Elliot-Penry L, AbouAssi H ... Diabetologia, 2015 | 152 | 2015 |
| Differential effects of various fish proteins in altering body weight, adiposity, inflammatory status, and insulin sensitivity in high-fat–fed rats G Pilon, J Ruzzin, LE Rioux, C Lavigne, PJ White, L Frøyland, H Jacques, ... Metabolism 60 (8), 1122-1130, 2011 | 137 | 2011 |
| Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis PJ White, P St-Pierre, A Charbonneau, PL Mitchell, E St-Amand, ... Nature medicine 20 (6), 664-669, 2014 | 135 | 2014 |
| Branched-chain amino acids in cardiovascular disease RW McGarrah, PJ White Nature Reviews Cardiology 20 (2), 77-89, 2023 | 110 | 2023 |
| Age-dependent impairment of glucose tolerance in the 3xTg-AD mouse model of Alzheimer’s disease M Vandal, PJ White, G Chevrier, C Tremblay, IS Amour, E Planel, ... The FASEB Journal 29 (10), 4273-4284, 2015 | 109 | 2015 |
| Feeding diversified protein sources exacerbates hepatic insulin resistance via increased gut microbial branched-chain fatty acids and mTORC1 signaling in obese mice BSY Choi, N Daniel, VP Houde, A Ouellette, B Marcotte, TV Varin, C Vors, ... Nature Communications 12 (1), 1-16, 2021 | 81 | 2021 |
| Endotoxin mediated-iNOS induction causes insulin resistance via ONOO− induced tyrosine nitration of IRS-1 in skeletal muscle G Pilon, A Charbonneau, PJ White, P Dallaire, M Perreault, S Kapur, ... PloS one 5 (12), e15912, 2010 | 81 | 2010 |
| Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart JM Walejko, BA Christopher, SB Crown, GF Zhang, A Pickar-Oliver, ... Nature Communications 12 (1), 1680, 2021 | 72 | 2021 |
| Muscle-Liver Trafficking of BCAA-Derived Nitrogen Underlies Obesity-Related Glycine Depletion PJ White, AL Lapworth, RW McGarrah, LC Kwee, SB Crown, O Ilkayeva, ... Cell Reports 33 (6), 108375, 2020 | 68 | 2020 |