Approximate simulation of coupled fast and slow reactions for stochastic chemical kinetics EL Haseltine, JB Rawlings The Journal of chemical physics 117 (15), 6959-6969, 2002 | 704 | 2002 |
Critical evaluation of extended Kalman filtering and moving-horizon estimation EL Haseltine, JB Rawlings Industrial & engineering chemistry research 44 (8), 2451-2460, 2005 | 664 | 2005 |
Synthetic gene circuits: design with directed evolution EL Haseltine, FH Arnold Annu. Rev. Biophys. Biomol. Struct. 36 (1), 1-19, 2007 | 163 | 2007 |
Two classes of quasi-steady-state model reductions for stochastic kinetics EA Mastny, EL Haseltine, JB Rawlings The Journal of chemical physics 127 (9), 2007 | 110 | 2007 |
Implications of rewiring bacterial quorum sensing EL Haseltine, FH Arnold Applied and environmental microbiology 74 (2), 437-445, 2008 | 95 | 2008 |
On the origins of approximations for stochastic chemical kinetics EL Haseltine, JB Rawlings The Journal of chemical physics 123 (16), 2005 | 93 | 2005 |
Ivacaftor in infants aged 4 to< 12 months with cystic fibrosis and a gating mutation. Results of a two-part phase 3 clinical trial JC Davies, CE Wainwright, GS Sawicki, MN Higgins, D Campbell, ... American journal of respiratory and critical care medicine 203 (5), 585-593, 2021 | 87 | 2021 |
Initialization strategies for optimization of dynamic systems SM Safdarnejad, JD Hedengren, NR Lewis, EL Haseltine Computers & Chemical Engineering 78, 39-50, 2015 | 67 | 2015 |
A phase 3 study of tezacaftor in combination with ivacaftor in children aged 6 through 11 years with cystic fibrosis S Walker, P Flume, J McNamara, M Solomon, M Chilvers, J Chmiel, ... Journal of Cystic Fibrosis 18 (5), 708-713, 2019 | 63 | 2019 |
A phase 3, double-blind, parallel-group study to evaluate the efficacy and safety of tezacaftor in combination with ivacaftor in participants 6 through 11 years of age with … JC Davies, I Sermet-Gaudelus, L Naehrlich, RS Harris, D Campbell, ... Journal of Cystic Fibrosis 20 (1), 68-77, 2021 | 62 | 2021 |
Dynamics of viral infections: incorporating both the intracellular and extracellular levels EL Haseltine, JB Rawlings, J Yin Computers & chemical engineering 29 (3), 675-686, 2005 | 60 | 2005 |
Image-guided modeling of virus growth and spread EL Haseltine, V Lam, J Yin, JB Rawlings Bulletin of mathematical biology 70, 1730-1748, 2008 | 48 | 2008 |
On the stochastic simulation of particulate systems EL Haseltine, DB Patience, JB Rawlings Chemical Engineering Science 60 (10), 2627-2641, 2005 | 42 | 2005 |
Physiologically based pharmacokinetic modeling of CFTR modulation in people with cystic fibrosis transitioning from mono or dual regimens to triple-combination elexacaftor … A Tsai, SP Wu, E Haseltine, S Kumar, SM Moskowitz, P Panorchan, ... Pulmonary therapy 6, 275-286, 2020 | 30 | 2020 |
Stochastic simulation of catalytic surface reactions in the fast diffusion limit EA Mastny, EL Haseltine, JB Rawlings The Journal of chemical physics 125 (19), 2006 | 27 | 2006 |
The stochastic quasi-steady-state assumption: reducing the model but not the noise R Srivastava, EL Haseltine, E Mastny, JB Rawlings The Journal of chemical physics 134 (15), 2011 | 24 | 2011 |
Successful treatment with telaprevir‐based regimens for chronic hepatitis C results in significant improvements to serum markers of liver fibrosis EL Haseltine, MS Penney, S George, TL Kieffer Journal of Viral Hepatitis 22 (9), 701-707, 2015 | 22 | 2015 |
Implications of decoupling the intracellular and extracellular levels in multi‐level models of virus growth EL Haseltine, J Yin, JB Rawlings Biotechnology and bioengineering 101 (4), 811-820, 2008 | 22 | 2008 |
Systems analysis of stochastic and population balance models for chemically reacting systems EL Haseltine The University of Wisconsin-Madison, 2005 | 21 | 2005 |
Pharmaceutical compositions for treating cystic fibrosis C Chu, V Dhamankar, E Dokou, EL Haseltine, S Moskowitz, S Robertson, ... US Patent 11,179,367, 2021 | 18 | 2021 |