| A human memory T cell subset with stem cell-like properties L Gattinoni, E Lugli, Y Ji, Z Pos, CM Paulos, MF Quigley, JR Almeida, ... Nature medicine 17 (10), 1290-1297, 2011 | 2172 | 2011 |
| Adoptive immunotherapy for cancer: building on success L Gattinoni, DJ Powell, SA Rosenberg, NP Restifo Nature Reviews Immunology 6 (5), 383-393, 2006 | 1961 | 2006 |
| Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells L Gattinoni, SE Finkelstein, CA Klebanoff, PA Antony, DC Palmer, ... The Journal of experimental medicine 202 (7), 907-912, 2005 | 1243 | 2005 |
| Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells L Gattinoni, CA Klebanoff, DC Palmer, C Wrzesinski, K Kerstann, Z Yu, ... The Journal of clinical investigation 115 (6), 1616-1626, 2005 | 1213 | 2005 |
| Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells CA Klebanoff, L Gattinoni, P Torabi-Parizi, K Kerstann, AR Cardones, ... Proceedings of the National Academy of Sciences 102 (27), 9571-9576, 2005 | 1211 | 2005 |
| Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells L Gattinoni, XS Zhong, DC Palmer, Y Ji, CS Hinrichs, Z Yu, C Wrzesinski, ... Nature medicine 15 (7), 808-813, 2009 | 1137 | 2009 |
| Tumor-specific Th17-polarized cells eradicate large established melanoma P Muranski, A Boni, PA Antony, L Cassard, KR Irvine, A Kaiser, ... Blood, The Journal of the American Society of Hematology 112 (2), 362-373, 2008 | 1046 | 2008 |
| Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function M Sukumar, J Liu, Y Ji, M Subramanian, JG Crompton, Z Yu, ... The Journal of clinical investigation 123 (10), 4479-4488, 2013 | 960 | 2013 |
| IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells CA Klebanoff, SE Finkelstein, DR Surman, MK Lichtman, L Gattinoni, ... Proceedings of the National Academy of Sciences 101 (7), 1969-1974, 2004 | 698 | 2004 |
| Paths to stemness: building the ultimate antitumour T cell L Gattinoni, CA Klebanoff, NP Restifo Nature Reviews Cancer 12 (10), 671-684, 2012 | 692 | 2012 |
| CD8+ T‐cell memory in tumor immunology and immunotherapy CA Klebanoff, L Gattinoni, NP Restifo Immunological reviews 211 (1), 214-224, 2006 | 664 | 2006 |
| Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling CM Paulos, C Wrzesinski, A Kaiser, CS Hinrichs, M Chieppa, L Cassard, ... The Journal of clinical investigation 117 (8), 2197-2204, 2007 | 641 | 2007 |
| The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemness T Wu, Y Ji, EA Moseman, HC Xu, M Manglani, M Kirby, SM Anderson, ... Science immunology 1 (6), eaai8593, 2016 | 551 | 2016 |
| IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy CS Hinrichs, R Spolski, CM Paulos, L Gattinoni, KW Kerstann, DC Palmer, ... Blood, The Journal of the American Society of Hematology 111 (11), 5326-5333, 2008 | 535 | 2008 |
| T memory stem cells in health and disease L Gattinoni, DE Speiser, M Lichterfeld, C Bonini Nature medicine 23 (1), 18-27, 2017 | 513 | 2017 |
| Th17 Cells Are Long Lived and Retain a Stem Cell-like Molecular Signature P Muranski, ZA Borman, SP Kerkar, CA Klebanoff, Y Ji, L Sanchez-Perez, ... Immunity 35 (6), 972-985, 2011 | 512 | 2011 |
| Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection C Yao, HW Sun, NE Lacey, Y Ji, EA Moseman, HY Shih, EF Heuston, ... Nature immunology 20 (7), 890-901, 2019 | 491 | 2019 |
| Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity CS Hinrichs, ZA Borman, L Cassard, L Gattinoni, R Spolski, Z Yu, ... Proceedings of the National Academy of Sciences 106 (41), 17469-17474, 2009 | 476 | 2009 |
| BACH2 represses effector programs to stabilize Treg-mediated immune homeostasis R Roychoudhuri, K Hirahara, K Mousavi, D Clever, CA Klebanoff, ... Nature 498 (7455), 506-510, 2013 | 443 | 2013 |
| Generation of clinical-grade CD19-specific CAR-modified CD8+ memory stem cells for the treatment of human B-cell malignancies M Sabatino, J Hu, M Sommariva, S Gautam, V Fellowes, JD Hocker, ... Blood, The Journal of the American Society of Hematology 128 (4), 519-528, 2016 | 391 | 2016 |
Nicholas P Restifo, MDCellular Immunotherapy ExplorerVerified email at marbletx.com