The nanomechanical signature of breast cancer M Plodinec, M Loparic, CA Monnier, EC Obermann, R Zanetti-Dallenbach, ... Nature nanotechnology 7 (11), 757-765, 2012 | 1163 | 2012 |
Tau protein disrupts nucleocytoplasmic transport in Alzheimer’s disease B Eftekharzadeh, JG Daigle, LE Kapinos, A Coyne, J Schiantarelli, ... Neuron 99 (5), 925-940. e7, 2018 | 407 | 2018 |
Nanomechanical basis of selective gating by the nuclear pore complex RYH Lim, B Fahrenkrog, J Köser, K Schwarz-Herion, J Deng, U Aebi Science 318 (5850), 640-643, 2007 | 343 | 2007 |
Flexible phenylalanine-glycine nucleoporins as entropic barriers to nucleocytoplasmic transport RYH Lim, NP Huang, J Köser, J Deng, KHA Lau, K Schwarz-Herion, ... Proceedings of the National Academy of Sciences 103 (25), 9512-9517, 2006 | 343 | 2006 |
Single-molecule transport across an individual biomimetic nuclear pore complex SW Kowalczyk, L Kapinos, TR Blosser, T Magalhães, P Van Nies, ... Nature nanotechnology 6 (7), 433-438, 2011 | 290 | 2011 |
Human GBP1 binds LPS to initiate assembly of a caspase-4 activating platform on cytosolic bacteria JC Santos, D Boucher, LK Schneider, B Demarco, M Dilucca, K Shkarina, ... Nature communications 11 (1), 3276, 2020 | 240 | 2020 |
Strongly stretched protein resistant poly (ethylene glycol) brushes prepared by grafting-to G Emilsson, RL Schoch, L Feuz, F Höök, RYH Lim, AB Dahlin ACS applied materials & interfaces 7 (14), 7505-7515, 2015 | 212 | 2015 |
Spatiotemporal dynamics of the nuclear pore complex transport barrier resolved by high-speed atomic force microscopy Y Sakiyama, A Mazur, LE Kapinos, RYH Lim Nature nanotechnology 11 (8), 719-723, 2016 | 174 | 2016 |
Towards reconciling structure and function in the nuclear pore complex RYH Lim, U Aebi, B Fahrenkrog Histochemistry and cell biology 129, 105-116, 2008 | 171 | 2008 |
Karyopherin-centric control of nuclear pores based on molecular occupancy and kinetic analysis of multivalent binding with FG nucleoporins LE Kapinos, RL Schoch, RS Wagner, KD Schleicher, RYH Lim Biophysical journal 106 (8), 1751-1762, 2014 | 141 | 2014 |
The nuclear pore complex up close RYH Lim, B Fahrenkrog Current opinion in cell biology 18 (3), 342-347, 2006 | 137 | 2006 |
Disordered proteinaceous machines M Fuxreiter, A Tóth-Petróczy, DA Kraut, AT Matouschek, RYH Lim, B Xue, ... Chemical reviews 114 (13), 6806-6843, 2014 | 128 | 2014 |
Nuclear transport receptor binding avidity triggers a self-healing collapse transition in FG-nucleoporin molecular brushes RL Schoch, LE Kapinos, RYH Lim Proceedings of the National Academy of Sciences 109 (42), 16911-16916, 2012 | 119 | 2012 |
Nanoscale topographic and biomechanical studies of the human internal limiting membrane PB Henrich, CA Monnier, W Halfter, C Haritoglou, RW Strauss, RYH Lim, ... Investigative ophthalmology & visual science 53 (6), 2561-2570, 2012 | 111 | 2012 |
Karyopherins regulate nuclear pore complex barrier and transport function LE Kapinos, B Huang, C Rencurel, RYH Lim Journal of Cell Biology 216 (11), 3609-3624, 2017 | 96 | 2017 |
Structural analysis of the nuclear pore complex by integrated approaches N Elad, T Maimon, D Frenkiel-Krispin, RYH Lim, O Medalia Current opinion in structural biology 19 (2), 226-232, 2009 | 95 | 2009 |
Biology and biophysics of the nuclear pore complex and its components RYH Lim, KS Ullman, B Fahrenkrog International review of cell and molecular biology 267, 299-342, 2008 | 95 | 2008 |
Simple biophysics underpins collective conformations of the intrinsically disordered proteins of the Nuclear Pore Complex A Vovk, C Gu, MG Opferman, LE Kapinos, RYH Lim, RD Coalson, ... Elife 5, e10785, 2016 | 78 | 2016 |
Promiscuous binding of Karyopherinβ1 modulates FG nucleoporin barrier function and expedites NTF2 transport kinetics RS Wagner, LE Kapinos, NJ Marshall, M Stewart, RYH Lim Biophysical journal 108 (4), 918-927, 2015 | 78 | 2015 |
Organelle-specific targeting of polymersomes into the cell nucleus C Zelmer, LP Zweifel, LE Kapinos, I Craciun, ZP Güven, CG Palivan, ... Proceedings of the National Academy of Sciences 117 (6), 2770-2778, 2020 | 73 | 2020 |