| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 14278* | 2021 |
| Survival in BRAF V600–mutant advanced melanoma treated with vemurafenib JA Sosman, KB Kim, L Schuchter, R Gonzalez, AC Pavlick, JS Weber, ... New England Journal of Medicine 366 (8), 707-714, 2012 | 2653 | 2012 |
| Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer C Twyman-Saint Victor, AJ Rech, A Maity, R Rengan, KE Pauken, ... Nature 520 (7547), 373-377, 2015 | 2480 | 2015 |
| T-cell invigoration to tumour burden ratio associated with anti-PD-1 response AC Huang, MA Postow, RJ Orlowski, R Mick, B Bengsch, S Manne, W Xu, ... Nature 545 (7652), 60-65, 2017 | 1631 | 2017 |
| Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma RK Amaravadi, D Yu, JJ Lum, T Bui, MA Christophorou, GI Evan, ... The Journal of clinical investigation 117 (2), 326-336, 2007 | 1443 | 2007 |
| TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion O Khan, JR Giles, S McDonald, S Manne, SF Ngiow, KP Patel, MT Werner, ... Nature 571 (7764), 211-218, 2019 | 1364 | 2019 |
| Autophagy in malignant transformation and cancer progression L Galluzzi, F Pietrocola, JM Bravo‐San Pedro, RK Amaravadi, ... The EMBO journal 34 (7), 856-880, 2015 | 1329 | 2015 |
| Tumor interferon signaling regulates a multigenic resistance program to immune checkpoint blockade JL Benci, B Xu, Y Qiu, TJ Wu, H Dada, C Twyman-Saint Victor, L Cucolo, ... Cell 167 (6), 1540-1554. e12, 2016 | 1155 | 2016 |
| Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth M Buzzai, RG Jones, RK Amaravadi, JJ Lum, RJ DeBerardinis, F Zhao, ... Cancer research 67 (14), 6745-6752, 2007 | 1149 | 2007 |
| Autophagy in major human diseases DJ Klionsky, G Petroni, RK Amaravadi, EH Baehrecke, A Ballabio, P Boya, ... The EMBO journal 40 (19), e108863, 2021 | 1148 | 2021 |
| Principles and current strategies for targeting autophagy for cancer treatment RK Amaravadi, J Lippincott-Schwartz, XM Yin, WA Weiss, N Takebe, ... Clinical cancer research 17 (4), 654-666, 2011 | 1053 | 2011 |
| Recent insights into the function of autophagy in cancer R Amaravadi, AC Kimmelman, E White Genes & development 30 (17), 1913-1930, 2016 | 830 | 2016 |
| Developmental relationships of four exhausted CD8+ T cell subsets reveals underlying transcriptional and epigenetic landscape control mechanisms JC Beltra, S Manne, MS Abdel-Hakeem, M Kurachi, JR Giles, Z Chen, ... Immunity 52 (5), 825-841. e8, 2020 | 790 | 2020 |
| Targeting autophagy in cancer: recent advances and future directions RK Amaravadi, AC Kimmelman, J Debnath Cancer discovery 9 (9), 1167-1181, 2019 | 786 | 2019 |
| Targeting autophagy in cancer AV Onorati, M Dyczynski, R Ojha, RK Amaravadi Cancer 124 (16), 3307-3318, 2018 | 731 | 2018 |
| A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma AC Huang, RJ Orlowski, X Xu, R Mick, SM George, PK Yan, S Manne, ... Nature medicine 25 (3), 454-461, 2019 | 635 | 2019 |
| The roles of therapy-induced autophagy and necrosis in cancer treatment RK Amaravadi, CB Thompson Clinical cancer research 13 (24), 7271-7279, 2007 | 621 | 2007 |
| Enhancing CD8+ T cell fatty acid catabolism within a metabolically challenging tumor microenvironment increases the efficacy of melanoma immunotherapy Y Zhang, R Kurupati, L Liu, XY Zhou, G Zhang, A Hudaihed, F Filisio, ... Cancer cell 32 (3), 377-391. e9, 2017 | 546 | 2017 |
| A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme MR Rosenfeld, X Ye, JG Supko, S Desideri, SA Grossman, S Brem, ... Autophagy 10 (8), 1359-1368, 2014 | 545 | 2014 |
| Phase II trial (BREAK-2) of the BRAF inhibitor dabrafenib (GSK2118436) in patients with metastatic melanoma PA Ascierto, D Minor, A Ribas, C Lebbe, A O'Hagan, N Arya, M Guckert, ... Journal of clinical oncology 31 (26), 3205-3211, 2013 | 527 | 2013 |