Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease F Liu, J Shi, H Tanimukai, J Gu, J Gu, I Grundke-Iqbal, K Iqbal, CX Gong Brain 132 (7), 1820-1832, 2009 | 486 | 2009 |
PP2A regulates tau phosphorylation directly and also indirectly via activating GSK-3β W Qian, J Shi, X Yin, K Iqbal, I Grundke-Iqbal, CX Gong, F Liu Journal of Alzheimer's Disease 19 (4), 1221-1229, 2010 | 203 | 2010 |
Increased Dosage of Dyrk1A Alters Alternative Splicing Factor (ASF)-regulated Alternative Splicing of Tau in Down Syndrome*♦ J Shi, T Zhang, C Zhou, MO Chohan, X Gu, J Wegiel, J Zhou, YW Hwang, ... Journal of Biological Chemistry 283 (42), 28660-28669, 2008 | 180 | 2008 |
PKA modulates GSK-3β-and cdk5-catalyzed phosphorylation of tau in site-and kinase-specific manners F Liu, Z Liang, J Shi, D Yin, E El-Akkad, I Grundke-Iqbal, K Iqbal, CX Gong FEBS letters 580 (26), 6269-6274, 2006 | 171 | 2006 |
APC is an RNA-binding protein, and its interactome provides a link to neural development and microtubule assembly N Preitner, J Quan, DW Nowakowski, ML Hancock, J Shi, J Tcherkezian, ... Cell 158 (2), 368-382, 2014 | 170 | 2014 |
Cross talk between PI3K-AKT-GSK-3β and PP2A pathways determines tau hyperphosphorylation Y Wang, R Yang, J Gu, X Yin, N Jin, S Xie, Y Wang, H Chang, W Qian, ... Neurobiology of aging 36 (1), 188-200, 2015 | 141 | 2015 |
Relevance of phosphorylation and truncation of tau to the etiopathogenesis of Alzheimer’s disease Y Zhou, J Shi, D Chu, W Hu, Z Guan, CX Gong, K Iqbal, F Liu Frontiers in aging neuroscience 10, 27, 2018 | 117 | 2018 |
Developmental regulation of protein O-GlcNAcylation, O-GlcNAc transferase, and O-GlcNAcase in mammalian brain Y Liu, X Li, Y Yu, J Shi, Z Liang, X Run, Y Li, C Dai, I Grundke-Iqbal, ... Public Library of Science 7 (8), e43724, 2012 | 112 | 2012 |
Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A W Qian, H Liang, J Shi, N Jin, I Grundke-Iqbal, K Iqbal, CX Gong, F Liu Nucleic acids research 39 (14), 6161-6171, 2011 | 110 | 2011 |
Dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) modulates serine/arginine-rich protein 55 (SRp55)-promoted Tau exon 10 inclusion X Yin, N Jin, J Gu, J Shi, J Zhou, CX Gong, K Iqbal, I Grundke-Iqbal, F Liu Journal of Biological Chemistry 287 (36), 30497-30506, 2012 | 104 | 2012 |
Cyclic AMP-dependent protein kinase regulates the alternative splicing of tau exon 10: a mechanism involved in tau pathology of Alzheimer disease J Shi, W Qian, X Yin, K Iqbal, I Grundke-Iqbal, X Gu, F Ding, CX Gong, ... Journal of Biological Chemistry 286 (16), 14639-14648, 2011 | 104 | 2011 |
O-GlcNAcylation regulates ischemia-induced neuronal apoptosis through AKT signaling J Shi, J Gu, C Dai, J Gu, X Jin, J Sun, K Iqbal, F Liu, CX Gong Scientific reports 5 (1), 14500, 2015 | 89 | 2015 |
Dyrk1A overexpression leads to increase of 3R-tau expression and cognitive deficits in Ts65Dn Down syndrome mice X Yin, N Jin, J Shi, Y Zhang, Y Wu, CX Gong, K Iqbal, F Liu Scientific reports 7 (1), 619, 2017 | 82 | 2017 |
Inhibition of protein synthesis alters protein degradation through activation of protein kinase B (AKT) CL Dai, J Shi, Y Chen, K Iqbal, F Liu, CX Gong Journal of Biological Chemistry 288 (33), 23875-23883, 2013 | 71 | 2013 |
O‐Glc NA cylation of protein kinase A catalytic subunits enhances its activity: a mechanism linked to learning and memory deficits in Alzheimer's disease S Xie, N Jin, J Gu, J Shi, J Sun, D Chu, L Zhang, C Dai, J Gu, CX Gong, ... Aging cell 15 (3), 455-464, 2016 | 70 | 2016 |
TDP-43 suppresses tau expression via promoting its mRNA instability J Gu, F Wu, W Xu, J Shi, W Hu, N Jin, W Qian, X Wang, K Iqbal, CX Gong, ... Nucleic acids research 45 (10), 6177-6193, 2017 | 61 | 2017 |
Truncation and activation of dual specificity tyrosine phosphorylation-regulated kinase 1A by calpain I: A molecular mechanism linked to tau pathology in Alzheimer disease N Jin, X Yin, J Gu, X Zhang, J Shi, W Qian, Y Ji, M Cao, X Gu, F Ding, ... Journal of Biological Chemistry 290 (24), 15219-15237, 2015 | 61 | 2015 |
Regulation of alternative splicing of tau exon 10 by 9G8 and Dyrk1A S Ding, J Shi, W Qian, K Iqbal, I Grundke-Iqbal, CX Gong, F Liu Neurobiology of aging 33 (7), 1389-1399, 2012 | 60 | 2012 |
Activation of protein phosphatase 2B and hyperphosphorylation of Tau in Alzheimer's disease W Qian, X Yin, W Hu, J Shi, J Gu, I Grundke-Iqbal, K Iqbal, CX Gong, F Liu Journal of Alzheimer's Disease 23 (4), 617-627, 2011 | 55 | 2011 |
Diverse regulation of AKT and GSK-3β by O-GlcNAcylation in various types of cells J Shi, S Wu, C Dai, Y Li, I Grundke-Iqbal, K Iqbal, F Liu, CX Gong FEBS letters 586 (16), 2443-2450, 2012 | 48 | 2012 |