| Endothelial TLR4 and the microbiome drive cerebral cavernous malformations AT Tang, JP Choi, JJ Kotzin, Y Yang, CC Hong, N Hobson, R Girard, ... Nature 545 (7654), 305-310, 2017 | 306 | 2017 |
| Cerebral cavernous malformations arise from endothelial gain of MEKK3–KLF2/4 signalling Z Zhou, AT Tang, WY Wong, S Bamezai, LM Goddard, R Shenkar, S Zhou, ... Nature 532 (7597), 122-126, 2016 | 297 | 2016 |
| Regulation of cardiovascular development and integrity by the heart of glass–cerebral cavernous malformation protein pathway B Kleaveland, X Zheng, JJ Liu, Y Blum, JJ Tung, Z Zou, SM Sweeney, ... Nature medicine 15 (2), 169-176, 2009 | 262 | 2009 |
| CCM3 signaling through sterile 20–like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations X Zheng, C Xu, A Di Lorenzo, B Kleaveland, Z Zou, C Seiler, M Chen, ... The Journal of clinical investigation 120 (8), 2795-2804, 2010 | 183 | 2010 |
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| Endothelial Foxp1 suppresses atherosclerosis via modulation of Nlrp3 inflammasome activation T Zhuang, J Liu, X Chen, L Zhang, J Pi, H Sun, L Li, R Bauer, H Wang, ... Circulation research 125 (6), 590-605, 2019 | 155 | 2019 |
| Aquaporin 3 colocates with phospholipase d2 in caveolin-rich membrane microdomains and is downregulated upon keratinocyte differentiation X Zheng, WB Bollag Journal of investigative dermatology 121 (6), 1487-1495, 2003 | 116 | 2003 |
| Aquaporin-3 in keratinocytes and skin: Its role and interaction with phospholipase D2 H Qin, X Zheng, X Zhong, AK Shetty, PM Elias, WB Bollag Archives of Biochemistry and Biophysics 508 (2), 138-143, 2011 | 104 | 2011 |
| A potential role for the phospholipase D2-aquaporin-3 signaling module in early keratinocyte differentiation: production of a phosphatidylglycerol signaling lipid WB Bollag, D Xie, X Zheng, X Zhong Journal of investigative dermatology 127 (12), 2823-2831, 2007 | 87 | 2007 |
| Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation AT Tang, KR Sullivan, CC Hong, LM Goddard, A Mahadevan, A Ren, ... Science translational medicine 11 (520), eaaw3521, 2019 | 76 | 2019 |
| Aquaporin 3, a glycerol and water transporter, is regulated by p73 of the p53 family X Zheng, X Chen FEBS letters 489 (1), 4-7, 2001 | 76 | 2001 |
| Endothelial forkhead box transcription factor P1 regulates pathological cardiac remodeling through transforming growth factor-β1–endothelin-1 signal pathway J Liu, T Zhuang, J Pi, X Chen, Q Zhang, Y Li, H Wang, Y Shen, ... Circulation 140 (8), 665-680, 2019 | 73 | 2019 |
| Dynamic regulation of the cerebral cavernous malformation pathway controls vascular stability and growth X Zheng, C Xu, AO Smith, AN Stratman, Z Zou, B Kleaveland, L Yuan, ... Developmental cell 23 (2), 342-355, 2012 | 60 | 2012 |
| Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformations JP Choi, R Wang, X Yang, X Wang, L Wang, KK Ting, M Foley, V Cogger, ... Science advances 4 (11), eaau0731, 2018 | 50 | 2018 |
| A MicroRNA302-367-Erk1/2-Klf2-S1pr1 pathway prevents tumor growth via restricting angiogenesis and improving vascular stability J Pi, T Tao, T Zhuang, H Sun, X Chen, J Liu, Y Cheng, Z Yu, HH Zhu, ... Circulation research 120 (1), 85-98, 2017 | 40 | 2017 |
| AngII induces transient phospholipase D activity in the H295R glomerulosa cell model X Zheng, WB Bollag Molecular and cellular endocrinology 206 (1-2), 113-122, 2003 | 40 | 2003 |
| Low fluid shear stress conditions contribute to activation of cerebral cavernous malformation signalling pathways J Li, Y Zhao, P Coleman, J Chen, KK Ting, JP Choi, X Zheng, MA Vadas, ... Biochimica Et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (11), 165519, 2019 | 39 | 2019 |
| Modulation of phospholipase D-mediated phosphatidylglycerol formation by differentiating agents in primary mouse epidermal keratinocytes X Zheng, S Ray, WB Bollag Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1643 (1-3), 25-36, 2003 | 39 | 2003 |
| Phospholipase D1 is required for angiogenesis of intersegmental blood vessels in zebrafish XXI Zeng, X Zheng, Y Xiang, HP Cho, JR Jessen, TP Zhong, ... Developmental biology 328 (2), 363-376, 2009 | 38 | 2009 |
| Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican CC Hong, AT Tang, MR Detter, JP Choi, R Wang, X Yang, AA Guerrero, ... Journal of Experimental Medicine 217 (10), e20200140, 2020 | 34 | 2020 |
Matthew FoleyThe University of SydneyVerified email at sydney.edu.au
