| Predicting the sequence specificities of DNA-and RNA-binding proteins by deep learning B Alipanahi, A Delong, MT Weirauch, BJ Frey Nature biotechnology 33 (8), 831-838, 2015 | 3143 | 2015 |
| Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies MA Nalls, C Blauwendraat, CL Vallerga, K Heilbron, S Bandres-Ciga, ... The Lancet Neurology 18 (12), 1091-1102, 2019 | 1832 | 2019 |
| Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use M Liu, Y Jiang, R Wedow, Y Li, DM Brazel, F Chen, G Datta, ... Nature genetics 51 (2), 237-244, 2019 | 1686 | 2019 |
| The human splicing code reveals new insights into the genetic determinants of disease HY Xiong, B Alipanahi, LJ Lee, H Bretschneider, D Merico, RKC Yuen, ... Science 347 (6218), 1254806, 2015 | 1471 | 2015 |
| Underspecification presents challenges for credibility in modern machine learning A D'Amour, K Heller, D Moldovan, B Adlam, B Alipanahi, A Beutel, ... Journal of Machine Learning Research 23 (226), 1-61, 2022 | 788 | 2022 |
| Widespread intron retention in mammals functionally tunes transcriptomes U Braunschweig, NL Barbosa-Morais, Q Pan, EN Nachman, B Alipanahi, ... Genome research 24 (11), 1774-1786, 2014 | 700 | 2014 |
| An atlas of genetic influences on osteoporosis in humans and mice JA Morris, JP Kemp, SE Youlten, L Laurent, JG Logan, RC Chai, ... Nature genetics 51 (2), 258-266, 2019 | 680 | 2019 |
| Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ... Nature genetics 51 (2), 245-257, 2019 | 658 | 2019 |
| Whole-genome sequencing expands diagnostic utility and improves clinical management in paediatric medicine DJ Stavropoulos, D Merico, R Jobling, S Bowdin, N Monfared, ... NPJ genomic medicine 1 (1), 1-9, 2016 | 385 | 2016 |
| MBNL proteins repress ES-cell-specific alternative splicing and reprogramming H Han, M Irimia, PJ Ross, HK Sung, B Alipanahi, L David, A Golipour, ... Nature 498 (7453), 241-245, 2013 | 355 | 2013 |
| Machine learning in genomic medicine: a review of computational problems and data sets MKK Leung, A Delong, B Alipanahi, BJ Frey Proceedings of the IEEE 104 (1), 176-197, 2015 | 342 | 2015 |
| Genome-wide characteristics of de novo mutations in autism RKC Yuen, D Merico, H Cao, G Pellecchia, B Alipanahi, ... NPJ genomic medicine 1 (1), 1-10, 2016 | 243 | 2016 |
| Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis B Schormair, C Zhao, S Bell, E Tilch, AV Salminen, B Pütz, Y Dauvilliers, ... The Lancet Neurology 16 (11), 898-907, 2017 | 228 | 2017 |
| Are random forests truly the best classifiers? M Wainberg, B Alipanahi, BJ Frey Journal of Machine Learning Research 17 (110), 1-5, 2016 | 204 | 2016 |
| A genetic investigation of sex bias in the prevalence of attention-deficit/hyperactivity disorder J Martin, RK Walters, D Demontis, M Mattheisen, SH Lee, E Robinson, ... Biological psychiatry 83 (12), 1044-1053, 2018 | 193 | 2018 |
| Brain-expressed exons under purifying selection are enriched for de novo mutations in autism spectrum disorder M Uddin, K Tammimies, G Pellecchia, B Alipanahi, P Hu, Z Wang, D Pinto, ... Nature genetics 46 (7), 742-747, 2014 | 177 | 2014 |
| Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells EL Bao, SK Nandakumar, X Liao, AG Bick, J Karjalainen, M Tabaka, ... Nature 586 (7831), 769-775, 2020 | 121 | 2020 |
| Systems and methods for classifying, prioritizing and interpreting genetic variants and therapies using a deep neural network B Frey, MKK Leung, AT Delong, HY Xiong, B Alipanahi, LJ Lee, ... US Patent 10,185,803, 2019 | 109 | 2019 |
| Common variant burden contributes to the familial aggregation of migraine in 1,589 families P Gormley, MI Kurki, ME Hiekkala, K Veerapen, P Häppölä, AA Mitchell, ... Neuron 98 (4), 743-753. e4, 2018 | 104 | 2018 |
| The effect of LRRK2 loss-of-function variants in humans N Whiffin, IM Armean, A Kleinman, JL Marshall, EV Minikel, JK Goodrich, ... Nature Medicine 26 (6), 869-877, 2020 | 102 | 2020 |
Brendan FreyFounder & CEO, Deep Genomics; Co-Founder, Vector Institute; Professor, University of TorontoVerified email at psi.toronto.edu