| Drug resistance via feedback activation of Stat3 in oncogene-addicted cancer cells HJ Lee, G Zhuang, Y Cao, P Du, HJ Kim, J Settleman Cancer cell 26 (2), 207-221, 2014 | 574 | 2014 |
| Tumour‐secreted miR‐9 promotes endothelial cell migration and angiogenesis by activating the JAK‐STAT pathway G Zhuang, X Wu, Z Jiang, I Kasman, J Yao, Y Guan, J Oeh, Z Modrusan, ... The EMBO journal 31 (17), 3513-3523, 2012 | 533 | 2012 |
| An interleukin-17–mediated paracrine network promotes tumor resistance to anti-angiogenic therapy AS Chung, X Wu, G Zhuang, H Ngu, I Kasman, J Zhang, JM Vernes, ... Nature medicine 19 (9), 1114-1123, 2013 | 496 | 2013 |
| The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling DM Brantley-Sieders, G Zhuang, D Hicks, WB Fang, Y Hwang, JMM Cates, ... The Journal of clinical investigation 118 (1), 64-78, 2008 | 325 | 2008 |
| Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy G Zhuang, DM Brantley-Sieders, D Vaught, J Yu, L Xie, S Wells, ... Cancer research 70 (1), 299-308, 2010 | 275 | 2010 |
| Molecular targeted therapies elicit concurrent apoptotic and GSDME-dependent pyroptotic tumor cell death H Lu, S Zhang, J Wu, M Chen, MC Cai, Y Fu, W Li, J Wang, X Zhao, Z Yu, ... Clinical Cancer Research 24 (23), 6066-6077, 2018 | 230 | 2018 |
| Impaired tumor microenvironment in EphA2‐deficient mice inhibits tumor angiogenesis and metastatic progression DM Brantley‐Sieders, WB Fang, DJ Hicks, G Zhuang, Y Shyr, J Chen The FASEB journal 19 (13), 1884-1886, 2005 | 201 | 2005 |
| Regulation of EphA2 receptor endocytosis by SHIP2 lipid phosphatase via phosphatidylinositol 3-Kinase-dependent Rac1 activation G Zhuang, S Hunter, Y Hwang, J Chen Journal of Biological Chemistry 282 (4), 2683-2694, 2007 | 171 | 2007 |
| Essential role of Vav family guanine nucleotide exchange factors in EphA receptor-mediated angiogenesis SG Hunter, G Zhuang, D Brantley-Sieders, W Swat, CW Cowan, J Chen Molecular and cellular biology, 2006 | 168 | 2006 |
| Multi-omics prediction of immune-related adverse events during checkpoint immunotherapy Y Jing, J Liu, Y Ye, L Pan, H Deng, Y Wang, Y Yang, L Diao, SH Lin, ... Nature communications 11 (1), 4946, 2020 | 156 | 2020 |
| Overexpression of EPHA2 receptor destabilizes adherens junctions via a RhoA-dependent mechanism WB Fang, RC Ireton, G Zhuang, T Takahashi, A Reynolds, J Chen Journal of cell science 121 (3), 358-368, 2008 | 153 | 2008 |
| Metabolic and transcriptional profiling reveals pyruvate dehydrogenase kinase 4 as a mediator of epithelial-mesenchymal transition and drug resistance in tumor cells Y Sun, A Daemen, G Hatzivassiliou, D Arnott, C Wilson, G Zhuang, M Gao, ... Cancer & metabolism 2, 1-14, 2014 | 143 | 2014 |
| Oncogenic RAS pathway activation promotes resistance to anti-VEGF therapy through G-CSF–induced neutrophil recruitment VT Phan, X Wu, JH Cheng, RX Sheng, AS Chung, G Zhuang, C Tran, ... Proceedings of the National Academy of Sciences 110 (15), 6079-6084, 2013 | 126 | 2013 |
| Deubiquitinase USP13 dictates MCL1 stability and sensitivity to BH3 mimetic inhibitors S Zhang, M Zhang, Y Jing, X Yin, P Ma, Z Zhang, X Wang, W Di, ... Nature communications 9 (1), 215, 2018 | 120 | 2018 |
| Expression of a functional VEGFR-1 in tumor cells is a major determinant of anti-PlGF antibodies efficacy J Yao, X Wu, G Zhuang, IM Kasman, T Vogt, V Phan, M Shibuya, ... Proceedings of the National Academy of Sciences 108 (28), 11590-11595, 2011 | 116 | 2011 |
| BET bromodomain inhibition as a therapeutic strategy in ovarian cancer by downregulating FoxM1 Z Zhang, P Ma, Y Jing, Y Yan, MC Cai, M Zhang, S Zhang, H Peng, ZL Ji, ... Theranostics 6 (2), 219, 2016 | 99 | 2016 |
| Differential drug class‐specific metastatic effects following treatment with a panel of angiogenesis inhibitors AS Chung, M Kowanetz, X Wu, G Zhuang, H Ngu, D Finkle, L Komuves, ... The Journal of pathology 227 (4), 404-416, 2012 | 97 | 2012 |
| Induction of Bv8 expression by granulocyte colony-stimulating factor in CD11b+ Gr1+ cells: key role of Stat3 signaling X Qu, G Zhuang, L Yu, G Meng, N Ferrara Journal of Biological Chemistry 287 (23), 19574-19584, 2012 | 97 | 2012 |
| Phosphoproteomic analysis implicates the mTORC2-FoxO1 axis in VEGF signaling and feedback activation of receptor tyrosine kinases G Zhuang, K Yu, Z Jiang, A Chung, J Yao, C Ha, K Toy, R Soriano, ... Science signaling 6 (271), ra25-ra25, 2013 | 94 | 2013 |
| Development of potent and selective inhibitors targeting the papain-like protease of SARS-CoV-2 H Shan, J Liu, J Shen, J Dai, G Xu, K Lu, C Han, Y Wang, X Xu, Y Tong, ... Cell chemical biology 28 (6), 855-865. e9, 2021 | 86 | 2021 |
Ying JingGreater Bay Area Institute of Precision Medicine (Guangzhou)Verified email at ipm-gba.org.cn