A central role for free heme in the pathogenesis of severe sepsis R Larsen, R Gozzelino, V Jeney, L Tokaji, FA Bozza, AM Japiassú, ... Science translational medicine 2 (51), 51ra71-51ra71, 2010 | 537 | 2010 |
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals A Giri, JN Hellwege, JM Keaton, J Park, C Qiu, HR Warren, ES Torstenson, ... Nature genetics 51 (1), 51-62, 2019 | 419 | 2019 |
Reappraisal of known malaria resistance loci in a large multicenter study Nature genetics 46 (11), 1197-1204, 2014 | 252 | 2014 |
European Network on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (EUROMENE): expert consensus on the diagnosis, service provision, and care of people with ME/CFS in Europe L Nacul, FJ Authier, C Scheibenbogen, L Lorusso, IB Helland, JA Martin, ... Medicina 57 (5), 510, 2021 | 174 | 2021 |
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals P Surendran, EV Feofanova, N Lahrouchi, I Ntalla, S Karthikeyan, J Cook, ... Nature genetics 52 (12), 1314-1332, 2020 | 159 | 2020 |
Plasmodium falciparum parasites with histidine-rich protein 2 (pfhrp2) and pfhrp3 gene deletions in two endemic regions of Kenya KB Beshir, N Sepúlveda, J Bharmal, A Robinson, J Mwanguzi, AO Busula, ... Scientific reports 7 (1), 14718, 2017 | 142 | 2017 |
Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study CM Ndila, S Uyoga, AW Macharia, G Nyutu, N Peshu, J Ojal, M Shebe, ... The Lancet Haematology 5 (8), e333-e345, 2018 | 126 | 2018 |
When three is not a crowd: a Crossregulation Model of the dynamics and repertoire selection of regulatory CD4+ T cells J Carneiro, K Leon, Í Caramalho, C Van Den Dool, R Gardner, V Oliveira, ... Immunological reviews 216 (1), 48-68, 2007 | 102 | 2007 |
African glucose-6-phosphate dehydrogenase alleles associated with protection from severe malaria in heterozygous females in Tanzania A Manjurano, N Sepulveda, B Nadjm, G Mtove, H Wangai, C Maxwell, ... PLoS genetics 11 (2), e1004960, 2015 | 100 | 2015 |
The low-virulent African swine fever virus (ASFV/NH/P68) induces enhanced expression and production of relevant regulatory cytokines (IFNα, TNFα and IL12p40) on porcine … S Gil, N Sepúlveda, E Albina, A Leitão, C Martins Archives of virology 153, 1845-1854, 2008 | 97 | 2008 |
Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia GM Clarke, K Rockett, K Kivinen, C Hubbart, AE Jeffreys, K Rowlands, ... elife 6, e15085, 2017 | 91 | 2017 |
Relevance of feline interferon omega for clinical improvement and reduction of concurrent viral excretion in retrovirus infected cats from a rescue shelter S Gil, RO Leal, A Duarte, D McGahie, N Sepúlveda, I Siborro, J Cravo, ... Research in veterinary science 94 (3), 753-763, 2013 | 87 | 2013 |
Dysregulated autoantibodies targeting vaso-and immunoregulatory receptors in Post COVID Syndrome correlate with symptom severity F Sotzny, IS Filgueiras, C Kedor, H Freitag, S Bauer, N Sepúlveda, ... Frontiers in immunology 13, 981532, 2022 | 84 | 2022 |
Variation in natural exposure to anopheles mosquitoes and its effects on malaria transmission WM Guelbeogo, BP Gonçalves, L Grignard, J Bradley, SS Serme, ... Elife 7, e32625, 2018 | 82 | 2018 |
Cellular immune function in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) JM Cliff, EC King, JS Lee, N Sepúlveda, AS Wolf, C Kingdon, E Bowman, ... Frontiers in immunology 10, 796, 2019 | 81 | 2019 |
Systematic review of the epidemiological burden of myalgic encephalomyelitis/chronic fatigue syndrome across Europe: current evidence and EUROMENE research recommendations for … F Estévez-López, K Mudie, X Wang-Steverding, IJ Bakken, A Ivanovs, ... Journal of clinical medicine 9 (5), 1557, 2020 | 76 | 2020 |
Optimisation and standardisation of a multiplex immunoassay of diverse Plasmodium falciparum antigens to assess changes in malaria transmission using sero-epidemiology L Wu, T Hall, I Ssewanyana, T Oulton, C Patterson, H Vasileva, S Singh, ... Wellcome open research 4, 26, 2020 | 72 | 2020 |
Novel genetic polymorphisms associated with severe malaria and under selective pressure in North-eastern Tanzania M Ravenhall, S Campino, N Sepúlveda, A Manjurano, B Nadjm, G Mtove, ... PLoS genetics 14 (1), e1007172, 2018 | 71 | 2018 |
A novel multiplex qPCR assay for detection of Plasmodium falciparum with histidine-rich protein 2 and 3 (pfhrp2 and pfhrp3) deletions in polyclonal infections L Grignard, D Nolder, N Sepúlveda, A Berhane, S Mihreteab, R Kaaya, ... EBioMedicine 55, 2020 | 69 | 2020 |
Candidate human genetic polymorphisms and severe malaria in a Tanzanian population A Manjurano, TG Clark, B Nadjm, G Mtove, H Wangai, N Sepulveda, ... PloS one 7 (10), e47463, 2012 | 66 | 2012 |