WNT signaling in disease LF Ng, P Kaur, N Bunnag, J Suresh, ICH Sung, QH Tan, J Gruber, ... Cells 8 (8), 826, 2019 | 244 | 2019 |
Conductance and amantadine binding of a pore formed by a lysine‐flanked transmembrane domain of SARS coronavirus envelope protein J Torres, U Maheswari, K Parthasarathy, L Ng, DX Liu, X Gong Protein science 16 (9), 2065-2071, 2007 | 217 | 2007 |
The mitochondria-targeted antioxidant MitoQ extends lifespan and improves healthspan of a transgenic Caenorhabditis elegans model of Alzheimer disease LF Ng, J Gruber, IK Cheah, CK Goo, WF Cheong, G Shui, KP Sit, ... Free Radical Biology and Medicine 71, 390-401, 2014 | 173 | 2014 |
Deceptively simple but simply deceptive–Caenorhabditis elegans lifespan studies: considerations for aging and antioxidant effects J Gruber, LF Ng, SK Poovathingal, B Halliwell FEBS letters 583 (21), 3377-3387, 2009 | 127 | 2009 |
Structure and ion channel activity of the human respiratory syncytial virus (hRSV) small hydrophobic protein transmembrane domain SW Gan, L Ng, X Lin, X Gong, J Torres Protein Science 17 (5), 813-820, 2008 | 122 | 2008 |
Ageing in nematodes: do antioxidants extend lifespan in Caenorhabditis elegans? PBL Pun, J Gruber, SY Tang, S Schaffer, RLS Ong, S Fong, LF Ng, ... Biogerontology 11, 17-30, 2010 | 116 | 2010 |
Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model S Fong, E Teo, LF Ng, CB Chen, LN Lakshmanan, SY Tsoi, PK Moore, ... Scientific reports 6 (1), 33781, 2016 | 107 | 2016 |
Hydrogen sulfide is an endogenous regulator of aging in Caenorhabditis elegans B Qabazard, L Li, J Gruber, MT Peh, LF Ng, SD Kumar, P Rose, CH Tan, ... Antioxidants & redox signaling 20 (16), 2621-2630, 2014 | 107 | 2014 |
Structural flexibility of the pentameric SARS coronavirus envelope protein ion channel K Parthasarathy, L Ng, X Lin, DX Liu, K Pervushin, X Gong, J Torres Biophysical journal 95 (6), L39-L41, 2008 | 101 | 2008 |
Mitochondrial changes in ageing Caenorhabditis elegans–what do we learn from superoxide dismutase knockouts? J Gruber, LF Ng, S Fong, YT Wong, SA Koh, CB Chen, G Shui, ... PloS one 6 (5), e19444, 2011 | 99 | 2011 |
Drug synergy slows aging and improves healthspan through IGF and SREBP lipid signaling TD Admasu, KC Batchu, D Barardo, LF Ng, VYM Lam, L Xiao, ... Developmental cell 47 (1), 67-79. e5, 2018 | 90 | 2018 |
Effects of Lithium on Age-related Decline in Mitochondrial Turnover and Function in Caenorhabditis elegans ZY Tam, J Gruber, LF Ng, B Halliwell, R Gunawan Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2014 | 61 | 2014 |
The effect of dichloroacetate on health- and lifespan in C. elegans S Schaffer, J Gruber, LF Ng, S Fong, YT Wong, SY Tang, B Halliwell Biogerontology 12, 195-209, 2011 | 58 | 2011 |
Caenorhabditis elegans: What We Can and Cannot Learn from Aging Worms J Gruber, CB Chen, S Fong, LF Ng, E Teo, B Halliwell Antioxidants & redox signaling 23 (3), 256-279, 2015 | 56 | 2015 |
Inhibition of amyloid‐induced toxicity by ergothioneine in a transgenic Caenorhabditis elegans model IK Cheah, LT Ng, LF Ng, VY Lam, J Gruber, CYW Huang, FQ Goh, ... FEBS letters 593 (16), 2139-2150, 2019 | 46 | 2019 |
Clonal expansion of mitochondrial DNA deletions is a private mechanism of aging in long‐lived animals LN Lakshmanan, Z Yee, LF Ng, R Gunawan, B Halliwell, J Gruber Aging Cell 17 (5), e12814, 2018 | 46 | 2018 |
Knockout of a putative ergothioneine transporter in Caenorhabditis elegans decreases lifespan and increases susceptibility to oxidative damage IK Cheah, RLS Ong, J Gruber, TSK Yew, LF Ng, CB Chen, B Halliwell Free Radical Research 47 (12), 1036-1045, 2013 | 46 | 2013 |
The role of mitochondrial non-enzymatic protein acylation in ageing SY Hong, LT Ng, LF Ng, T Inoue, NS Tolwinski, T Hagen, J Gruber PLoS One 11 (12), e0168752, 2016 | 34 | 2016 |
Lifespan and healthspan benefits of exogenous H2S in C. elegans are independent from effects downstream of eat-2 mutation LT Ng, LF Ng, RMY Tang, D Barardo, B Halliwell, PK Moore, J Gruber NPJ aging and mechanisms of disease 6 (1), 6, 2020 | 33 | 2020 |
Repression of the mitochondrial peroxiredoxin antioxidant system does not shorten life span but causes reduced fitness in Caenorhabditis elegans M Ranjan, J Gruber, LF Ng, B Halliwell Free Radical Biology and Medicine 63, 381-389, 2013 | 32 | 2013 |