Sebastian Bruchmann

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Andreas DötschScientist, Max Rubner-InstituteVerified email at mri.bund.de
Denitsa EckweilerVerified email at tu-braunschweig.de
Taane G. ClarkProfessor of Genomics & Global Health, London School of Hygiene and Tropical MedicineVerified email at lshtm.ac.uk
Gabriel CabotResearcherVerified email at ssib.es
Bartolome MoyaBalearic Islands Health Research Institute (IdISBa)Verified email at ssib.es
Carlos Juan Immunology associate professor (UIB), Microbiology Researcher Hospital Son Espases, PalmaVerified email at uib.cat
Laura ZamoranoResearcher Son Espases HospitalVerified email at ssib.es
Antonio OliverMicrobiology, Hospital Son Espases, Instituto de Investigación Sanitaria Illes Balears (IdISBa)Verified email at ssib.es
Xavier MuletMicrobiology Hospital Son Dureta / Hospital Son EspasesVerified email at ssib.es
Prof. Dr. med. Iris F. ChabernyUniv.-Professorin für Hygiene und Umweltmedizin, Universitätsklinikum LeipzigVerified email at medizin.uni-leipzig.de
Raimo FrankeScientist, Helmholtz Centre for Infection ResearchVerified email at helmholtz-hzi.de
Julian ParkhillUniversity of CambridgeVerified email at cam.ac.uk
Richard A StablerLondon School of Hygiene and Tropical MedicineVerified email at lshtm.ac.uk
Lucy van DorpUCL Genetics InstituteVerified email at ucl.ac.uk
Neil WoodfordUK Health Security AgencyVerified email at phe.gov.uk
Liam P. ShawUniversity of OxfordVerified email at biology.ox.ac.uk
Jacob Moran GiladBen-Gurion University of the NegevVerified email at post.bgu.ac.il
Ronan DoyleClinical Bioinformatician, SynnovisVerified email at synnovis.co.uk
Jim F HuggettNational Measurement Laboratory/University of SurreyVerified email at lgcgroup.com
Matthew EllingtonUK Health Security AgencyVerified email at phe.gov.uk

Sebastian Bruchmann

Senior Research Associate, Department of Veterinary Medicine, University of Cambridge

Verified email at cam.ac.uk - Homepage

microbiology functional genomics antimicrobial resistance pathogenicity & host-pathogen interactions


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Pseudomonas aeruginosa ceftolozane-tazobactam resistance development requires multiple mutations leading to overexpression and structural modification of AmpC G Cabot, S Bruchmann, X Mulet, L Zamorano, B Moyà, C Juan, ... Antimicrobial agents and chemotherapy 58 (6), 3091-3099, 2014	257	2014
Quantitative contributions of target alteration and decreased drug accumulation to Pseudomonas aeruginosa fluoroquinolone resistance S Bruchmann, A Dötsch, B Nouri, IF Chaberny, S Häussler Antimicrobial agents and chemotherapy 57 (3), 1361-1368, 2013	183	2013
Elucidation of Sigma Factor-Associated Networks in Pseudomonas aeruginosa Reveals a Modular Architecture with Limited and Function-Specific Crosstalk S Schulz, D Eckweiler, A Bielecka, T Nicolai, R Franke, A Doetsch, ... PLoS pathogens 11 (3), e1004744, 2015	156	2015
Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: an inter-laboratory study RM Doyle, DM O'sullivan, SD Aller, S Bruchmann, T Clark, ... Microbial genomics 6 (2), e000335, 2020	113	2020
Transcriptome profiling of antimicrobial resistance in Pseudomonas aeruginosa A Khaledi, M Schniederjans, S Pohl, R Rainer, U Bodenhofer, B Xia, ... Antimicrobial agents and chemotherapy 60 (8), 4722-4733, 2016	100	2016
Radically different phylogeographies and patterns of genetic variation in two European brown frogs, genus Rana M Vences, JS Hauswaldt, S Steinfartz, O Rupp, A Goesmann, S Künzel, ... Molecular phylogenetics and evolution 68 (3), 657-670, 2013	86	2013
Mining zebrafish microbiota reveals key community-level resistance against fish pathogen infection FA Stressmann, J Bernal-Bayard, D Perez-Pascual, B Audrain, ... The ISME journal 15 (3), 702-719, 2021	56	2021
BACTOME—a reference database to explore the sequence- and gene expression-variation landscape of Pseudomonas aeruginosa clinical isolates K Hornischer, A Khaledi, S Pohl, M Schniederjans, L Pezoldt, F Casilag, ... Nucleic acids research 47 (D1), D716-D720, 2019	49	2019
Identifying virulence determinants of multidrug-resistant Klebsiella pneumoniae in Galleria mellonella S Bruchmann, T Feltwell, J Parkhill, FL Short Pathogens and disease 79 (3), ftab009, 2021	42	2021
Deep transcriptome profiling of clinical Klebsiella pneumoniae isolates reveals strain and sequence type‐specific adaptation S Bruchmann, U Muthukumarasamy, S Pohl, M Preusse, A Bielecka, ... Environmental microbiology 17 (11), 4690-4710, 2015	29	2015
Importance of flagella in acute and chronic Pseudomonas aeruginosa infections A Lorenz, M Preuße, S Bruchmann, V Pawar, N Grahl, MC Pils, LM Nolan, ... Environmental microbiology 21 (3), 883-897, 2019	23	2019
Spatiotemporal control of FlgZ activity impacts Pseudomonas aeruginosa flagellar motility S Bense, S Bruchmann, A Steffen, TEB Stradal, S Häussler, J Düvel Molecular Microbiology 111 (6), 1544-1557, 2019	19	2019
The emergence and diversification of a zoonotic pathogen from within the microbiota of intensively farmed pigs GGR Murray, ASMM Hossain, EL Miller, S Bruchmann, AJ Balmer, ... Proceedings of the National Academy of Sciences 120 (47), e2307773120, 2023	18	2023
PowerBacGWAS: a computational pipeline to perform power calculations for bacterial genome-wide association studies F Coll, T Gouliouris, S Bruchmann, J Phelan, KE Raven, TG Clark, ... Communications Biology 5 (1), 266, 2022	16	2022
Mutation rate dynamics reflect ecological change in an emerging zoonotic pathogen GGR Murray, AJ Balmer, J Herbert, NF Hadjirin, CL Kemp, ... PLoS Genetics 17 (11), e1009864, 2021	9	2021
Rapid antimicrobial susceptibility testing and phylogenetic identification S Häussler, S Bruchmann, D Chesnel US Patent App. 16/477,794, 2019	3	2019
Antibiotic resistance and pathogenicity in the Gram-negative bacteria Pseudomonas aeruginosa and Klebsiella pneumoniae S Bruchmann	1	2015

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