| Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis Y Ionov, MA Peinado, S Malkhosyan, D Shibata, M Perucho Nature 363 (6429), 558-561, 1993 | 3481 | 1993 |
| Most human carcinomas of the exocrine pancreas contain mutant cK-ras genes C Almoguera, D Shibata, K Forrester, J Martin, N Arnheim, M Perucho Cell 53 (4), 549-554, 1988 | 2827 | 1988 |
| Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype N Rampino, H Yamamoto, Y Ionov, Y Li, H Sawai, JC Reed, M Perucho Science 275 (5302), 967-969, 1997 | 1798 | 1997 |
| A National Cancer Institute workshop on hereditary nonpolyposis colorectal cancer syndrome: meeting highlights and Bethesda guidelines MA Rodriguez-Bigas, CR Boland, SR Hamilton, DE Henson, S Srivastava, ... Journal of the National Cancer Institute 89 (23), 1758-1762, 1997 | 1436 | 1997 |
| Detection of high incidence of K-ras oncogenes during human colon tumorigenesis K Forrester, C Almoguera, K Han, WE Grizzle, M Perucho Nature 327 (6120), 298-303, 1987 | 1423 | 1987 |
| Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells M Goldfarb, K Shimizu, M Perucho, M Wigler Nature 296 (5856), 404-409, 1982 | 668 | 1982 |
| Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation D Shibata, MA Peinado, Y lonov, S Malkhosyan, M Perucho Nature genetics 6 (3), 273-281, 1994 | 629 | 1994 |
| Human-tumor-derived cell lines contain common and different transforming genes M Perucho, M Goldfarb, K Shimizu, C Lama, J Fogh, M Wigler Cell 27 (3), 467-476, 1981 | 582 | 1981 |
| Three human transforming genes are related to the viral ras oncogenes. K Shimizu, M Goldfarb, Y Suard, M Perucho, Y Li, T Kamata, J Feramisco, ... Proceedings of the National Academy of Sciences 80 (8), 2112-2116, 1983 | 550 | 1983 |
| Genetic and physical linkage of exogenous sequences in transformed cells M Perucho, D Hanahan, M Wigler Cell 22 (1), 309-317, 1980 | 530 | 1980 |
| The somatic replication of DNA methylation M Wigler, D Levy, M Perucho Cell 24 (1), 33-40, 1981 | 494 | 1981 |
| A method to detect and characterize point mutations in transcribed genes: amplification and overexpression of the mutant c-Ki-ras allele in human tumor cells. E Winter, F Yamamoto, C Almoguera, M Perucho Proceedings of the National Academy of Sciences 82 (22), 7575-7579, 1985 | 445 | 1985 |
| Isolation and preliminary characterization of the transforming gene of a human neuroblastoma cell line. K Shimizu, M Goldfarb, M Perucho, M Wigler Proceedings of the National Academy of Sciences 80 (2), 383-387, 1983 | 423 | 1983 |
| Frameshift mutator mutations S Malkhosyan, N Rampino, H Yamamoto, M Perucho Nature 382 (6591), 499-500, 1996 | 402 | 1996 |
| Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction. MA Peinado, S Malkhosyan, A Velazquez, M Perucho Proceedings of the National Academy of Sciences 89 (21), 10065-10069, 1992 | 400 | 1992 |
| Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability. A Umar, JC Boyer, DC Thomas, DC Nguyen, JI Risinger, J Boyd, Y Ionov, ... Journal of Biological Chemistry 269 (20), 14367-14370, 1994 | 392 | 1994 |
| Cancer of the microsatellite mutator phenotype M Perucho BIOLOGICAL CHEMISTRY HOPPE SEYLER 377, 675-684, 1996 | 354 | 1996 |
| Frameshift somatic mutations in gastrointestinal cancer of the microsatellite mutator phenotype H Yamamoto, H Sawai, M Perucho Cancer research 57 (19), 4420-4426, 1997 | 331 | 1997 |
| Mutational inactivation of the proapoptotic gene BAX confers selective advantage during tumor clonal evolution Y Ionov, H Yamamoto, S Krajewski, JC Reed, M Perucho Proceedings of the National Academy of Sciences 97 (20), 10872-10877, 2000 | 326 | 2000 |
| Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage K Suzuki, I Suzuki, A Leodolter, S Alonso, S Horiuchi, K Yamashita, ... Cancer cell 9 (3), 199-207, 2006 | 325 | 2006 |