| In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance MA Schroeder, LE Cochlin, LC Heather, K Clarke, GK Radda, DJ Tyler Proceedings of the National Academy of Sciences 105 (33), 12051-12056, 2008 | 312 | 2008 |
| Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy MA Schroeder, HJ Atherton, DR Ball, MA Cole, LC Heather, JL Griffin, ... The FASEB journal 23 (8), 2529, 2009 | 270 | 2009 |
| A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart MA Cole, AJ Murray, LE Cochlin, LC Heather, S McAleese, NS Knight, ... Basic research in cardiology 106, 447-457, 2011 | 219 | 2011 |
| An essential cell-autonomous role for hepcidin in cardiac iron homeostasis S Lakhal-Littleton, M Wolna, YJ Chung, HC Christian, LC Heather, ... Elife 5, e19804, 2016 | 192 | 2016 |
| Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin LS Mansor, ER Gonzalez, MA Cole, DJ Tyler, JH Beeson, K Clarke, ... Cardiovascular diabetology 12, 1-10, 2013 | 183 | 2013 |
| Fatty acid transporter levels and palmitate oxidation rate correlate with ejection fraction in the infarcted rat heart LC Heather, MA Cole, CA Lygate, RD Evans, DJ Stuckey, AJ Murray, ... Cardiovascular research 72 (3), 430-437, 2006 | 173 | 2006 |
| Metabolism, hypoxia and the diabetic heart LC Heather, K Clarke Journal of molecular and cellular cardiology 50 (4), 598-605, 2011 | 152 | 2011 |
| Isoproterenol induces in vivo functional and metabolic abnormalities; similar to those found in the infarcted rat heart LC Heather, AF Catchpole, DJ Stuckey, MA Cole, CA Carr, K Clarke Acta Physiologica Polonica 12 (3), 31, 2009 | 136 | 2009 |
| Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined 13C Hyperpolarized Magnetic Resonance and … LM Le Page, OJ Rider, AJ Lewis, V Ball, K Clarke, E Johansson, CA Carr, ... Diabetes 64 (8), 2735-2743, 2015 | 135 | 2015 |
| Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: a combined magnetic resonance imaging and hyperpolarized magnetic … HJ Atherton, MS Dodd, LC Heather, MA Schroeder, JL Griffin, GK Radda, ... Circulation 123 (22), 2552-2561, 2011 | 130 | 2011 |
| Metabolic adaptation to chronic hypoxia in cardiac mitochondria LC Heather, MA Cole, JJ Tan, LJA Ambrose, S Pope, AH Abd-Jamil, ... Basic research in cardiology 107, 1-12, 2012 | 126 | 2012 |
| Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism L O'Flaherty, J Adam, LC Heather, AV Zhdanov, YL Chung, MX Miranda, ... Human molecular genetics 19 (19), 3844-3851, 2010 | 117 | 2010 |
| Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS HJ Atherton, MA Schroeder, MS Dodd, LC Heather, EE Carter, LE Cochlin, ... NMR in Biomedicine 24 (2), 201-208, 2011 | 116 | 2011 |
| In vivo alterations in cardiac metabolism and function in the spontaneously hypertensive rat heart MS Dodd, DR Ball, MA Schroeder, LM Le Page, HJ Atherton, LC Heather, ... Cardiovascular research 95 (1), 69-76, 2012 | 115 | 2012 |
| Hypoxia-inducible factor 1 signalling, metabolism and its therapeutic potential in cardiovascular disease MLS Fialho, AH Abd Jamil, GA Stannard, LC Heather Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (4), 831-843, 2019 | 109 | 2019 |
| A practical guide to metabolomic profiling as a discovery tool for human heart disease LC Heather, X Wang, JA West, JL Griffin Journal of molecular and cellular cardiology 55, 2-11, 2013 | 96 | 2013 |
| Differential translocation of the fatty acid transporter, FAT/CD36, and the glucose transporter, GLUT4, coordinates changes in cardiac substrate metabolism during ischemia and … LC Heather, KM Pates, HJ Atherton, MA Cole, DR Ball, RD Evans, ... Circulation: Heart Failure 6 (5), 1058-1066, 2013 | 88 | 2013 |
| Impaired in vivo mitochondrial Krebs cycle activity after myocardial infarction assessed using hyperpolarized magnetic resonance spectroscopy MS Dodd, HJ Atherton, CA Carr, DJ Stuckey, JA West, JL Griffin, ... Circulation: Cardiovascular Imaging 7 (6), 895-904, 2014 | 82 | 2014 |
| Critical role of complex III in the early metabolic changes following myocardial infarction LC Heather, CA Carr, DJ Stuckey, S Pope, KJ Morten, EE Carter, ... Cardiovascular research 85 (1), 127-136, 2010 | 81 | 2010 |
| Fatty acids prevent hypoxia-inducible factor-1α signaling through decreased succinate in diabetes MS Dodd, ML Sousa Fialho, CN Montes Aparicio, M Kerr, KN Timm, ... JACC: Basic to Translational Science 3 (4), 485-498, 2018 | 76 | 2018 |