| Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions VG Gorgoulis, LVF Vassiliou, P Karakaidos, P Zacharatos, A Kotsinas, ... Nature 434 (7035), 907-913, 2005 | 2422 | 2005 |
| Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints J Bartkova, N Rezaei, M Liontos, P Karakaidos, D Kletsas, N Issaeva, ... Nature 444 (7119), 633-637, 2006 | 2332 | 2006 |
| Molecular mechanisms of biological aging in intervertebral discs NV Vo, RA Hartman, PR Patil, MV Risbud, D Kletsas, JC Iatridis, ... Journal of orthopaedic research 34 (8), 1289-1306, 2016 | 408 | 2016 |
| Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues EA Georgakopoulou, K Tsimaratou, K Evangelou, MPJ Fernandez, ... Aging (Albany NY) 5 (1), 37, 2012 | 389 | 2012 |
| The bone-specific transcriptional regulator Cbfa1 is a target of mechanical signals in osteoblastic cells PG Ziros, APR Gil, T Georgakopoulos, I Habeos, D Kletsas, EK Basdra, ... Journal of Biological Chemistry 277 (26), 23934-23941, 2002 | 370 | 2002 |
| Senescence in human intervertebral discs S Roberts, EH Evans, D Kletsas, DC Jaffray, SM Eisenstein European Spine Journal 15, 312-316, 2006 | 369 | 2006 |
| Human fibroblast alterations induced by low power laser irradiation at the single cell level using confocal microscopy E Alexandratou, D Yova, P Handris, D Kletsas, S Loukas Photochemical & Photobiological Sciences 1, 547-552, 2002 | 315 | 2002 |
| Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing P Galanos, K Vougas, D Walter, A Polyzos, A Maya-Mendoza, ... Nature cell biology 18 (7), 777-789, 2016 | 306 | 2016 |
| Oxidative stress inhibits the proliferation, induces premature senescence and promotes a catabolic phenotype in human nucleus pulposus intervertebral disc cells A Dimozi, E Mavrogonatou, A Sklirou, D Kletsas Eur Cell Mater 30 (89), 102, 2015 | 286 | 2015 |
| Inflammatory and catabolic signalling in intervertebral discs: the roles of NF-κB and MAP kinases K Wuertz, N Vo, D Kletsas, N Boos European Cells and Materials 23, 103-119; discussion 119, 2012 | 267 | 2012 |
| Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior M Liontos, M Koutsami, M Sideridou, K Evangelou, D Kletsas, B Levy, ... Cancer research 67 (22), 10899-10909, 2007 | 249 | 2007 |
| Robust, universal biomarker assay to detect senescent cells in biological specimens K Evangelou, N Lougiakis, SV Rizou, A Kotsinas, D Kletsas, ... Aging cell 16 (1), 192-197, 2017 | 239 | 2017 |
| Resveratrol and related stilbenes: their anti-aging and anti-angiogenic properties KM Kasiotis, H Pratsinis, D Kletsas, SA Haroutounian Food and Chemical Toxicology 61, 112-120, 2013 | 236 | 2013 |
| Bioactive non-coloured polyphenols content of grapes, wines and vinification by-products: Evaluation of the antioxidant activities of their extracts M Anastasiadi, H Pratsinis, D Kletsas, AL Skaltsounis, SA Haroutounian Food research international 43 (3), 805-813, 2010 | 230 | 2010 |
| Mechanical loading of the intervertebral disc: from the macroscopic to the cellular level C Neidlinger-Wilke, F Galbusera, H Pratsinis, E Mavrogonatou, A Mietsch, ... European Spine Journal 23, 333-343, 2014 | 213 | 2014 |
| Characterization and cytotoxicity of ions released from stainless steel and nickel-titanium orthodontic alloys T Eliades, H Pratsinis, D Kletsas, G Eliades, M Makou American Journal of Orthodontics and Dentofacial Orthopedics 125 (1), 24-29, 2004 | 209 | 2004 |
| PDGF, bFGF and IGF-I stimulate the proliferation of intervertebral disc cells in vitro via the activation of the ERK and Akt signaling pathways H Pratsinis, D Kletsas European Spine Journal 16, 1858-1866, 2007 | 206 | 2007 |
| Intracellular clusterin inhibits mitochondrial apoptosis by suppressing p53-activating stress signals and stabilizing the cytosolic Ku70-Bax protein complex IP Trougakos, M Lourda, MH Antonelou, D Kletsas, VG Gorgoulis, ... Clinical cancer research 15 (1), 48-59, 2009 | 201 | 2009 |
| Transcription factor E2F‐1 acts as a growth‐promoting factor and is associated with adverse prognosis in non‐small cell lung carcinomas VG Gorgoulis, P Zacharatos, G Mariatos, A Kotsinas, M Bouda, D Kletsas, ... The Journal of pathology 198 (2), 142-156, 2002 | 191 | 2002 |
| Grape stem extracts: Polyphenolic content and assessment of their in vitro antioxidant properties M Anastasiadi, H Pratsinis, D Kletsas, AL Skaltsounis, SA Haroutounian LWT-Food Science and Technology 48 (2), 316-322, 2012 | 182 | 2012 |
