Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules WRJD Galloway, A Isidro-Llobet, DR Spring Nature communications 1 (1), 80, 2010 | 887 | 2010 |
Quorum sensing in Gram-negative bacteria: small-molecule modulation of AHL and AI-2 quorum sensing pathways WRJD Galloway, JT Hodgkinson, SD Bowden, M Welch, DR Spring Chemical reviews 111 (1), 28-67, 2011 | 779 | 2011 |
Palladium-catalysed cross-coupling of organosilicon reagents HF Sore, WRJD Galloway, DR Spring Chemical Society Reviews 41 (5), 1845-1866, 2012 | 413 | 2012 |
Applications of small molecule activators and inhibitors of quorum sensing in Gram-negative bacteria WRJD Galloway, JT Hodgkinson, S Bowden, M Welch, DR Spring Trends in microbiology 20 (9), 449-458, 2012 | 250 | 2012 |
A question of library design PJ Hajduk, WRJD Galloway, DR Spring Nature 470 (7332), 42-43, 2011 | 136 | 2011 |
A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody–drug conjugates SJ Walsh, S Omarjee, WRJD Galloway, TTL Kwan, HF Sore, JS Parker, ... Chemical Science 10 (3), 694-700, 2019 | 135 | 2019 |
Diversity-oriented synthesis of macrocyclic peptidomimetics A Isidro-Llobet, T Murillo, P Bello, A Cilibrizzi, JT Hodgkinson, ... Proceedings of the National Academy of Sciences 108 (17), 6793-6798, 2011 | 130 | 2011 |
The discovery of antibacterial agents using diversity-oriented synthesis WRJD Galloway, A Bender, M Welch, DR Spring Chemical communications, 2446-2462, 2009 | 106 | 2009 |
How diverse are diversity assessment methods? A comparative analysis and benchmarking of molecular descriptor space A Koutsoukas, S Paricharak, WRJD Galloway, DR Spring, AP IJzerman, ... Journal of chemical information and modeling 54 (1), 230-242, 2014 | 95 | 2014 |
Inhibition of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells by quorum sensing autoinducer-mimics B Morkunas, WRJD Galloway, M Wright, BM Ibbeson, JT Hodgkinson, ... Organic & Biomolecular Chemistry 10 (42), 8452-8464, 2012 | 94 | 2012 |
A two-component'double-click'approach to peptide stapling YH Lau, Y Wu, P De Andrade, WRJD Galloway, DR Spring Nature Protocols 10 (4), 585-594, 2015 | 90 | 2015 |
Design, synthesis and biological evaluation of non-natural modulators of quorum sensing in Pseudomonas aeruginosa JT Hodgkinson, WRJD Galloway, M Wright, IK Mati, RL Nicholson, ... Organic & biomolecular chemistry 10 (30), 6032-6044, 2012 | 83 | 2012 |
Structure-Activity Analysis of the Pseudomonas Quinolone Signal Molecule J Hodgkinson, SD Bowden, WRJD Galloway, DR Spring, M Welch Journal of bacteriology 192 (14), 3833-3837, 2010 | 70 | 2010 |
Is synthesis the main hurdle for the generation of diversity in compound libraries for screening? WRJD Galloway, DR Spring Expert Opinion on Drug Discovery 4 (5), 467-472, 2009 | 69 | 2009 |
Partially Saturated Bicyclic Heteroaromatics as an sp3‐Enriched Fragment Collection DG Twigg, N Kondo, SL Mitchell, WRJD Galloway, HF Sore, A Madin, ... Angewandte Chemie 128 (40), 12667-12671, 2016 | 67 | 2016 |
Skeletal diversity construction via a branching synthetic strategy EE Wyatt, S Fergus, WRJD Galloway, A Bender, DJ Fox, AT Plowright, ... Chemical communications, 3296-3298, 2006 | 65 | 2006 |
Microwave and flow syntheses of Pseudomonas quinolone signal (PQS) and analogues JT Hodgkinson, WRJD Galloway, S Saraf, IR Baxendale, SV Ley, ... Organic & Biomolecular Chemistry 9 (1), 57-61, 2011 | 63 | 2011 |
Visible-light-induced trifluoromethylation of highly functionalized arenes and heteroarenes in continuous flow I Abdiaj, C Bottecchia, J Alcazar, T Noёl Synthesis 49 (22), 4978-4985, 2017 | 57 | 2017 |
Synthesis of unprecedented scaffold diversity WRJD Galloway, M Diáz‐Gavilán, A Isidro‐Llobet, DR Spring Angewandte Chemie International Edition 48 (7), 1194-1196, 2009 | 57 | 2009 |
Robust routes for the synthesis of N-acylated-L-homoserine lactone (AHL) quorum sensing molecules with high levels of enantiomeric purity JT Hodgkinson, WRJD Galloway, M Casoli, H Keane, X Su, ... Tetrahedron letters 52 (26), 3291-3294, 2011 | 54 | 2011 |