| Molecular features of the copper binding sites in the octarepeat domain of the prion protein CS Burns, E Aronoff-Spencer, CM Dunham, P Lario, NI Avdievich, ... Biochemistry 41 (12), 3991-4001, 2002 | 499 | 2002 |
| Stable heterodimeric antibody design with mutations in the Fc domain TS Von Kreudenstein, EE Cabrera, SB Dixit, PI Lario, DKY Poon US Patent 9,562,109, 2017 | 331 | 2017 |
| Improving biophysical properties of a bispecific antibody scaffold to aid developability: quality by molecular design TS Von Kreudenstein, E Escobar-Carbrera, PI Lario, I D’Angelo, K Brault, ... MAbs 5 (5), 646-654, 2013 | 172 | 2013 |
| Sub-atomic resolution crystal structure of cholesterol oxidase: what atomic resolution crystallography reveals about enzyme mechanism and the role of the FAD cofactor in redox … PI Lario, N Sampson, A Vrielink Journal of molecular biology 326 (5), 1635-1650, 2003 | 172 | 2003 |
| The bacterial virulence factor NleA inhibits cellular protein secretion by disrupting mammalian COPII function J Kim, A Thanabalasuriar, T Chaworth-Musters, JC Fromme, EA Frey, ... Cell host & microbe 2 (3), 160-171, 2007 | 135 | 2007 |
| Antibodies with enhanced or suppressed effector function I D'angelo, D Bleile, SAL Tom-Yew, E Escobar-Cabrera, PI Lario, A Ohrn, ... US Patent 9,296,815, 2016 | 112 | 2016 |
| Conformational difference between PDE4 apoenzyme and holoenzyme F Laliberté, Y Han, A Govindarajan, A Giroux, S Liu, B Bobechko, P Lario, ... Biochemistry 39 (21), 6449-6458, 2000 | 107 | 2000 |
| Structure and biochemical analysis of a secretin pilot protein PI Lario, RA Pfuetzner, EA Frey, L Creagh, C Haynes, AT Maurelli, ... The EMBO journal 24 (6), 1111-1121, 2005 | 83 | 2005 |
| Structural characterization of the type-III pilot-secretin complex from Shigella flexneri M Okon, TF Moraes, PI Lario, AL Creagh, CA Haynes, NCJ Strynadka, ... Structure 16 (10), 1544-1554, 2008 | 77 | 2008 |
| Structural characterization of the RNase E S1 domain and identification of its oligonucleotide-binding and dimerization interfaces M Schubert, RE Edge, P Lario, MA Cook, NCJ Strynadka, GA Mackie, ... Journal of molecular biology 341 (1), 37-54, 2004 | 67 | 2004 |
| Dissecting the cofactor-dependent and independent bindings of PDE4 inhibitors S Liu, F Laliberté, B Bobechko, A Bartlett, P Lario, E Gorseth, ... Biochemistry 40 (34), 10179-10186, 2001 | 59 | 2001 |
| The presence of a hydrogen bond between asparagine 485 and the π system of FAD modulates the redox potential in the reaction catalyzed by cholesterol oxidase Y Yin, NS Sampson, A Vrielink, PI Lario Biochemistry 40 (46), 13779-13787, 2001 | 49 | 2001 |
| Atomic resolution crystallography reveals how changes in pH shape the protein microenvironment AY Lyubimov, PI Lario, I Moustafa, A Vrielink Nature chemical biology 2 (5), 259-264, 2006 | 45 | 2006 |
| Engineered immunoglobulin heavy chain-light chain pairs and uses thereof AL Corper, D Urosev, SAL Tom-Yew, DWB Bleile, TS Von Kreudenstein, ... US Patent 9,914,785, 2018 | 43 | 2018 |
| Atomic resolution density maps reveal secondary structure dependent differences in electronic distribution PI Lario, A Vrielink Journal of the American Chemical Society 125 (42), 12787-12794, 2003 | 41 | 2003 |
| Protein engineering and the use of molecular modeling and simulation: the case of heterodimeric Fc engineering TS Von Kreudenstein, PI Lario, SB Dixit Methods 65 (1), 77-94, 2014 | 32 | 2014 |
| In vitro PKA phosphorylation‐mediated human PDE4A4 activation F Laliberté, S Liu, E Gorseth, B Bobechko, A Bartlett, P Lario, MJ Gresser, ... FEBS letters 512 (1-3), 205-208, 2002 | 29 | 2002 |
| Heteromultimer constructs of immunoglobulin heavy chains with mutations in the fc domain TS Von Kreudenstein, E Escobar-Cabrera, GYK Ng, SB Dixit, PI Lario, ... US Patent App. 14/989,648, 2016 | 28 | 2016 |
| Heteromultimer constructs of immunoglobulin heavy chains with mutations in the fc domain TS VON KREUDENSTEIN, E Escobar-Cabrera, GYK Ng, SB Dixit, PI Lario, ... | 27 | 2013 |
| A new synthesis of in situ cyclopropanones and the observation of a thermal cyclopropanone–dienol rearrangement C Black, P Lario, AP Masters, TS Sorensen, F Sun Canadian journal of chemistry 71 (11), 1910-1918, 1993 | 21 | 1993 |
Alice VrielinkUniversity of Western AustraliaVerified email at uwa.edu.au