Antibodies to surface dopamine-2 receptor in autoimmune movement and psychiatric disorders RC Dale, V Merheb, S Pillai, D Wang, L Cantrill, TK Murphy, H Ben-Pazi, ... Brain 135 (11), 3453-3468, 2012 | 419 | 2012 |
Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease T Fath, J Eidenmüller, R Brandt Journal of Neuroscience 22 (22), 9733-9741, 2002 | 296 | 2002 |
Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia LM Ittner, T Fath, YD Ke, M Bi, J Van Eersel, KM Li, P Gunning, J Götz Proceedings of the National Academy of Sciences 105 (41), 15997-16002, 2008 | 250 | 2008 |
Primary support cultures of hippocampal and substantia nigra neurons T Fath, YD Ke, P Gunning, J Götz, LM Ittner Nature protocols 4 (1), 78-85, 2009 | 223 | 2009 |
A novel class of anticancer compounds targets the actin cytoskeleton in tumor cells JR Stehn, NK Haass, T Bonello, M Desouza, G Kottyan, H Treutlein, ... Cancer research 73 (16), 5169-5182, 2013 | 204 | 2013 |
Tropomyosin isoforms and reagents G Schevzov, SP Whittaker, T Fath, JJC Lin, PW Gunning Bioarchitecture 1 (4), 135-164, 2011 | 182 | 2011 |
Phosphorylation-mimicking glutamate clusters in the proline-rich region are sufficient to simulate the functional deficiencies of hyperphosphorylated tau protein J Eidenmüller, T Fath, T Maas, M Pool, E Sontag, R Brandt Biochemical Journal 357 (3), 759-767, 2001 | 169 | 2001 |
Tau exacerbates excitotoxic brain damage in an animal model of stroke M Bi, A Gladbach, J Van Eersel, A Ittner, M Przybyla, A Van Hummel, ... Nature communications 8 (1), 473, 2017 | 168 | 2017 |
A Caenorhabditis elegans model of tau hyperphosphorylation: induction of developmental defects by transgenic overexpression of Alzheimer's disease-like modified tau R Brandt, A Gergou, I Wacker, T Fath, H Hutter Neurobiology of aging 30 (1), 22-33, 2009 | 149 | 2009 |
Structural and functional implications of tau hyperphosphorylation: information from phosphorylation-mimicking mutated tau proteins J Eidenmüller, T Fath, A Hellwig, J Reed, E Sontag, R Brandt Biochemistry 39 (43), 13166-13175, 2000 | 149 | 2000 |
A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism N Turner, XY Lim, HD Toop, B Osborne, AE Brandon, EN Taylor, ... Nature communications 9 (1), 3165, 2018 | 128 | 2018 |
Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve-injured mice RS Tonkin, C Bowles, CJ Perera, BA Keating, PGS Makker, SS Duffy, ... Experimental neurology 300, 1-12, 2018 | 124 | 2018 |
Loss of ceramide synthase 2 activity, necessary for myelin biosynthesis, precedes tau pathology in the cortical pathogenesis of Alzheimer's disease TA Couttas, N Kain, AK Suchowerska, LE Quek, N Turner, T Fath, ... Neurobiology of aging 43, 89-100, 2016 | 92 | 2016 |
CYLD is a causative gene for frontotemporal dementia – amyotrophic lateral sclerosis C Dobson-Stone, M Hallupp, H Shahheydari, AMG Ragagnin, ... Brain 143 (3), 783-799, 2020 | 77 | 2020 |
Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments G Schevzov, AJ Kee, B Wang, VB Sequeira, J Hook, JD Coombes, ... Molecular biology of the cell 26 (13), 2475-2490, 2015 | 77 | 2015 |
Cell elasticity is regulated by the tropomyosin isoform composition of the actin cytoskeleton I Jalilian, C Heu, H Cheng, H Freittag, M Desouza, JR Stehn, NS Bryce, ... PloS one 10 (5), e0126214, 2015 | 64 | 2015 |
Tropomodulins are negative regulators of neurite outgrowth T Fath, RS Fischer, L Dehmelt, S Halpain, VM Fowler European journal of cell biology 90 (4), 291-300, 2011 | 61 | 2011 |
Divergent regulation of the sarcomere and the cytoskeleton G Schevzov, T Fath, B Vrhovski, N Vlahovich, S Rajan, J Hook, JE Joya, ... Journal of Biological Chemistry 283 (1), 275-283, 2008 | 46 | 2008 |
Functional diversity of actin cytoskeleton in neurons and its regulation by tropomyosin G Schevzov, NM Curthoys, PW Gunning, T Fath International review of cell and molecular biology 298, 33-94, 2012 | 45 | 2012 |
Functional identity of the gamma tropomyosin gene: Implications for embryonic development, reproduction and cell viability J Hook, F Lemckert, G Schevzov, T Fath, P Gunning Bioarchitecture 1 (1), 49-59, 2011 | 39 | 2011 |