| Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase J Du, Y Zhou, X Su, JJ Yu, S Khan, H Jiang, J Kim, J Woo, JH Kim, ... Science 334 (6057), 806-809, 2011 | 1484 | 2011 |
| SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine H Jiang, S Khan, Y Wang, G Charron, B He, C Sebastian, J Du, R Kim, ... Nature 496 (7443), 110-113, 2013 | 780 | 2013 |
| Protein lipidation: occurrence, mechanisms, biological functions, and enabling technologies H Jiang, X Zhang, X Chen, P Aramsangtienchai, Z Tong, H Lin Chemical reviews 118 (3), 919-988, 2018 | 419 | 2018 |
| Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation BA Gibson, Y Zhang, H Jiang, KM Hussey, JH Shrimp, H Lin, F Schwede, ... Science 353 (6294), 45-50, 2016 | 352 | 2016 |
| PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins YF Yongjia Duan, Aiying Du, Jinge Gu, Gang Duan, Chen Wang, Xinrui Gui ... Cell Research 29 (3), 233-247, 2019 | 229 | 2019 |
| Investigating the ADP-ribosyltransferase Activity of Sirtuins with NAD Analogues and 32P-NAD J Du, H Jiang, H Lin Biochemistry 48 (13), 2878-2890, 2009 | 218 | 2009 |
| Clickable NAD analogues for labeling substrate proteins of poly (ADP-ribose) polymerases H Jiang, JH Kim, KM Frizzell, WL Kraus, H Lin Journal of the American Chemical Society 132 (27), 9363-9372, 2010 | 162 | 2010 |
| Identifying the functional contribution of the defatty-acylase activity of SIRT6 X Zhang, S Khan, H Jiang, MA Antonyak, X Chen, NA Spiegelman, ... Nature chemical biology 12 (8), 614-620, 2016 | 92 | 2016 |
| Revealing CD38 cellular localization using a cell permeable, mechanism-based fluorescent small-molecule probe JH Shrimp, J Hu, M Dong, BS Wang, R MacDonald, H Jiang, Q Hao, ... Journal of the American Chemical Society 136 (15), 5656-5663, 2014 | 69 | 2014 |
| Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase Q Liu, R Graeff, IA Kriksunov, H Jiang, B Zhang, N Oppenheimer, H Lin, ... Journal of Biological Chemistry 284 (40), 27637-27645, 2009 | 69 | 2009 |
| Structure of a NADH-insensitive hexameric citrate synthase that resists acid inactivation JA Francois, CM Starks, S Sivanuntakorn, H Jiang, AE Ransome, JW Nam, ... Biochemistry 45 (45), 13487-13499, 2006 | 61 | 2006 |
| Covalent and noncovalent intermediates of an NAD utilizing enzyme, human CD38 Q Liu, IA Kriksunov, H Jiang, R Graeff, H Lin, HC Lee, Q Hao Chemistry & biology 15 (10), 1068-1078, 2008 | 60 | 2008 |
| Rapamycin targets STAT3 and impacts c-Myc to suppress tumor growth YZ Le Sun, Yu Yan, Heng Lv, Jianlong Li, Zhiyuan Wang, Kun Wang, Lin Wang ... Cell Chemical Biology, 2021 | 49* | 2021 |
| ZDHHC12-mediated claudin-3 S-palmitoylation determines ovarian cancer progression QH Meng Yuan, Xiaobing Chen, Yitang Sun, Li Jiang, Zhongni Xia, Kaixiong Ye ... Acta Pharmaceutica Sinica B 10 (8), 1426-1439, 2020 | 44 | 2020 |
| Lysine fatty acylation promotes lysosomal targeting of TNF-α H Jiang, X Zhang, H Lin Scientific Reports 6 (1), 1-10, 2016 | 42 | 2016 |
| Mechanism-based small molecule probes for labeling CD38 on live cells H Jiang, J Congleton, Q Liu, P Merchant, F Malavasi, HC Lee, Q Hao, ... Journal of the American Chemical Society 131 (5), 1658-1659, 2009 | 42 | 2009 |
| ATRA-induced HL-60 myeloid leukemia cell differentiation depends on the CD38 cytosolic tail needed for membrane localization, but CD38 enzymatic activity is unnecessary J Congleton, H Jiang, F Malavasi, H Lin, A Yen Experimental cell research 317 (7), 910-919, 2011 | 37 | 2011 |
| YBR246W is required for the third step of diphthamide biosynthesis X Su, W Chen, W Lee, H Jiang, S Zhang, H Lin Journal of the American Chemical Society 134 (2), 773-776, 2012 | 34 | 2012 |
| Ubiquitylome study identifies increased histone 2A ubiquitylation as an evolutionarily conserved aging biomarker YZ Lu Yang, Zaijun Ma, Han Wang, Kongyan Niu, Ye Cao, Le Sun, Yang Geng, Bo ... Nat Communications 10 (1), 2191, 2019 | 31 | 2019 |
| Chemogenomic approach identified yeast YLR143W as diphthamide synthetase X Su, Z Lin, W Chen, H Jiang, S Zhang, H Lin Proceedings of the National Academy of Sciences 109 (49), 19983-19987, 2012 | 29 | 2012 |
