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Zhaoren He
Zhaoren He
Biomap
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Year
Non-coding transcription instructs chromatin folding and compartmentalization to dictate enhancer-promoter communication and T cell fate
T Isoda, AJ Moore, Z He, V Chandra, M Aida, M Denholtz, ...
Cell 171 (1), 103-119. e18, 2017
3052017
Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing
B Kakaradov, J Arsenio, CE Widjaja, Z He, S Aigner, PJ Metz, B Yu, ...
Nature immunology 18 (4), 422-432, 2017
2662017
Heterogenous populations of tissue-resident CD8+ T cells are generated in response to infection and malignancy
JJ Milner, C Toma, Z He, NS Kurd, QP Nguyen, B McDonald, L Quezada, ...
Immunity 52 (5), 808-824. e7, 2020
2272020
Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses
BS Boland*, Z He*, MS Tsai*, JG Olvera, KD Omilusik, HG Duong, ES Kim, ...
Science immunology 5 (50), eabb4432, 2020
2132020
Early precursors and molecular determinants of tissue-resident memory CD8+ T lymphocytes revealed by single-cell RNA sequencing
NS Kurd*, Z He*, TL Louis, JJ Milner, KD Omilusik, W Jin, MS Tsai, ...
Science immunology 5 (47), eaaz6894, 2020
1922020
Highly efficient editing of the actinorhodin polyketide chain length factor gene in Streptomyces coelicolor M145 using CRISPR/Cas9-CodA(sm) combined system
H Zeng, S Wen, W Xu, Z He, G Zhai, Y Liu, Z Deng, Y Sun
Applied microbiology and biotechnology 99, 10575-10585, 2015
1712015
Tissue-resident memory CD8+ T cells possess unique transcriptional, epigenetic and functional adaptations to different tissue environments
JT Crowl, M Heeg, A Ferry, JJ Milner, KD Omilusik, C Toma, Z He, ...
Nature immunology 23 (7), 1121-1131, 2022
1622022
Integrin Activation Controls Regulatory T Cell–Mediated Peripheral Tolerance
JE Klann, SH Kim, KA Remedios, Z He, PJ Metz, J Lopez, T Tysl, ...
The Journal of Immunology, ji1800112, 2018
382018
The long noncoding RNA Malat1 regulates CD8+ T cell differentiation by mediating epigenetic repression
JN Kanbar, S Ma, ES Kim, NS Kurd, MS Tsai, T Tysl, CE Widjaja, ...
Journal of Experimental Medicine 219 (6), 2022
342022
Upon microbial challenge, human neutrophils undergo rapid changes in nuclear architecture and chromatin folding to orchestrate an immediate inflammatory gene program
M Denholtz, Y Zhu, Z He, H Lu, T Isoda, S Döhrmann, V Nizet, C Murre
Genes & development 34 (3-4), 149-165, 2020
332020
Plasma cell fate is orchestrated by elaborate changes in genome compartmentalization and inter-chromosomal hubs
A Bortnick*, Z He*, M Aubrey, V Chandra, M Denholtz, K Chen, YC Lin, ...
Cell reports 31 (1), 2020
302020
Early transcriptional and epigenetic divergence of CD8+ T cells responding to acute versus chronic infection
LK Quezada, W Jin, YC Liu, ES Kim, Z He, CS Indralingam, T Tysl, ...
PLoS biology 21 (1), e3001983, 2023
202023
Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors
Y Luo, Y Xia, D Liu, X Li, H Li, J Liu, D Zhou, Y Dong, X Li, Y Qian, C Xu, ...
Cell 187 (18), 4905-4925. e24, 2024
172024
Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses. Sci. Immunol. 5, eabb4432
BS Boland, Z He, MS Tsai, JG Olvera, KD Omilusik, HG Duong, ES Kim, ...
112020
Active maintenance of CD8+ T cell naivety through regulation of global genome architecture
BE Russ, A Barugahare, P Dakle, K Tsyganov, S Quon, B Yu, J Li, ...
Cell reports 42 (10), 2023
82023
Functional delineation of tissue-resident CD8+ T cell heterogeneity during infection and cancer
JJ Milner, C Toma, Z He, NS Kurd, QP Nguyen, B McDonald, L Quezada, ...
bioRxiv, 2020.03. 05.979146, 2020
32020
CTCF is necessary for CD8+ effector T cell differentiation
SJ Quon, B Yu, Z He, B Russ, SJ Turner, C Murre, AW Goldrath
The Journal of Immunology 202 (1_Supplement), 125.6-125.6, 2019
22019
Multistage regulator based on tandem promoters and CRISPR/Cas
H Jia, T Liang, Z Wang, Z He, Y Liu, L Yang, Y Zeng, S Liu, L Tang, ...
ACS synthetic biology 3 (12), 1007-1010, 2014
22014
Detecting the presence of a tumor based on methylation status of cell-free nucleic acid molecules
Y He, Z HE, A JAIMOVICH, W Walter, Y GREENWALD, WJ GREENLEAF, ...
US Patent WO2023197004A1, 2023
2023
CRISPR/Cas9 screening identified novel membrane targets sensitizing hepatocellular carcinoma cells to natural killer cell-mediated cytotoxicity
S Li, L Han, S Zhang, G Geng, L Huo, D Huang, Z He, S Li, Z Jiang, ...
Cancer Research 83 (7_Supplement), 3967-3967, 2023
2023
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