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Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing B Kakaradov, J Arsenio, CE Widjaja, Z He, S Aigner, PJ Metz, B Yu, ... Nature immunology 18 (4), 422-432, 2017 | 266 | 2017 |
Heterogenous populations of tissue-resident CD8+ T cells are generated in response to infection and malignancy JJ Milner, C Toma, Z He, NS Kurd, QP Nguyen, B McDonald, L Quezada, ... Immunity 52 (5), 808-824. e7, 2020 | 227 | 2020 |
Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses BS Boland*, Z He*, MS Tsai*, JG Olvera, KD Omilusik, HG Duong, ES Kim, ... Science immunology 5 (50), eabb4432, 2020 | 213 | 2020 |
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Highly efficient editing of the actinorhodin polyketide chain length factor gene in Streptomyces coelicolor M145 using CRISPR/Cas9-CodA(sm) combined system H Zeng, S Wen, W Xu, Z He, G Zhai, Y Liu, Z Deng, Y Sun Applied microbiology and biotechnology 99, 10575-10585, 2015 | 171 | 2015 |
Tissue-resident memory CD8+ T cells possess unique transcriptional, epigenetic and functional adaptations to different tissue environments JT Crowl, M Heeg, A Ferry, JJ Milner, KD Omilusik, C Toma, Z He, ... Nature immunology 23 (7), 1121-1131, 2022 | 162 | 2022 |
Integrin Activation Controls Regulatory T Cell–Mediated Peripheral Tolerance JE Klann, SH Kim, KA Remedios, Z He, PJ Metz, J Lopez, T Tysl, ... The Journal of Immunology, ji1800112, 2018 | 38 | 2018 |
The long noncoding RNA Malat1 regulates CD8+ T cell differentiation by mediating epigenetic repression JN Kanbar, S Ma, ES Kim, NS Kurd, MS Tsai, T Tysl, CE Widjaja, ... Journal of Experimental Medicine 219 (6), 2022 | 34 | 2022 |
Upon microbial challenge, human neutrophils undergo rapid changes in nuclear architecture and chromatin folding to orchestrate an immediate inflammatory gene program M Denholtz, Y Zhu, Z He, H Lu, T Isoda, S Döhrmann, V Nizet, C Murre Genes & development 34 (3-4), 149-165, 2020 | 33 | 2020 |
Plasma cell fate is orchestrated by elaborate changes in genome compartmentalization and inter-chromosomal hubs A Bortnick*, Z He*, M Aubrey, V Chandra, M Denholtz, K Chen, YC Lin, ... Cell reports 31 (1), 2020 | 30 | 2020 |
Early transcriptional and epigenetic divergence of CD8+ T cells responding to acute versus chronic infection LK Quezada, W Jin, YC Liu, ES Kim, Z He, CS Indralingam, T Tysl, ... PLoS biology 21 (1), e3001983, 2023 | 20 | 2023 |
Neoadjuvant PARPi or chemotherapy in ovarian cancer informs targeting effector Treg cells for homologous-recombination-deficient tumors Y Luo, Y Xia, D Liu, X Li, H Li, J Liu, D Zhou, Y Dong, X Li, Y Qian, C Xu, ... Cell 187 (18), 4905-4925. e24, 2024 | 17 | 2024 |
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Active maintenance of CD8+ T cell naivety through regulation of global genome architecture BE Russ, A Barugahare, P Dakle, K Tsyganov, S Quon, B Yu, J Li, ... Cell reports 42 (10), 2023 | 8 | 2023 |
Functional delineation of tissue-resident CD8+ T cell heterogeneity during infection and cancer JJ Milner, C Toma, Z He, NS Kurd, QP Nguyen, B McDonald, L Quezada, ... bioRxiv, 2020.03. 05.979146, 2020 | 3 | 2020 |
CTCF is necessary for CD8+ effector T cell differentiation SJ Quon, B Yu, Z He, B Russ, SJ Turner, C Murre, AW Goldrath The Journal of Immunology 202 (1_Supplement), 125.6-125.6, 2019 | 2 | 2019 |
Multistage regulator based on tandem promoters and CRISPR/Cas H Jia, T Liang, Z Wang, Z He, Y Liu, L Yang, Y Zeng, S Liu, L Tang, ... ACS synthetic biology 3 (12), 1007-1010, 2014 | 2 | 2014 |
Detecting the presence of a tumor based on methylation status of cell-free nucleic acid molecules Y He, Z HE, A JAIMOVICH, W Walter, Y GREENWALD, WJ GREENLEAF, ... US Patent WO2023197004A1, 2023 | | 2023 |
CRISPR/Cas9 screening identified novel membrane targets sensitizing hepatocellular carcinoma cells to natural killer cell-mediated cytotoxicity S Li, L Han, S Zhang, G Geng, L Huo, D Huang, Z He, S Li, Z Jiang, ... Cancer Research 83 (7_Supplement), 3967-3967, 2023 | | 2023 |