| A SARS-CoV-2 protein interaction map reveals targets for drug repurposing DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ... Nature 583 (7816), 459-468, 2020 | 4671 | 2020 |
| EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy BA Barad, N Echols, RYR Wang, Y Cheng, F DiMaio, PD Adams, ... Nature methods 12 (10), 943-946, 2015 | 792 | 2015 |
| Promoting transparency and reproducibility in enhanced molecular simulations M Bonomi, G Bussi, C Camilloni, GA Tribello, P Banáš, A Barducci, ... Nature methods 16 (8), 670-673, 2019 | 772 | 2019 |
| Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 669 | 2020 |
| Large language models generate functional protein sequences across diverse families A Madani, B Krause, ER Greene, S Subramanian, BP Mohr, JM Holton, ... Nature Biotechnology 41 (8), 1099-1106, 2023 | 655 | 2023 |
| Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine BB Williams, AH Van Benschoten, P Cimermancic, MS Donia, ... Cell host & microbe 16 (4), 495-503, 2014 | 633 | 2014 |
| Accessing protein conformational ensembles using room-temperature X-ray crystallography JS Fraser, H van den Bedem, AJ Samelson, PT Lang, JM Holton, ... Proceedings of the National Academy of Sciences 108 (39), 16247-16252, 2011 | 622 | 2011 |
| Hidden alternative structures of proline isomerase essential for catalysis JS Fraser, MW Clarkson, SC Degnan, R Erion, D Kern, T Alber Nature 462 (7273), 669-673, 2009 | 557 | 2009 |
| Systematic functional prioritization of protein posttranslational modifications P Beltrao, V Albanèse, LR Kenner, DL Swaney, A Burlingame, J Villén, ... Cell 150 (2), 413-425, 2012 | 455 | 2012 |
| Automated structure refinement of macromolecular assemblies from cryo-EM maps using Rosetta RYR Wang, Y Song, BA Barad, Y Cheng, JS Fraser, F DiMaio Elife 5, e17219, 2016 | 435 | 2016 |
| Effects of α-tubulin acetylation on microtubule structure and stability L Eshun-Wilson, R Zhang, D Portran, MV Nachury, DB Toso, T Löhr, ... Proceedings of the National Academy of Sciences 116 (21), 10366-10371, 2019 | 316 | 2019 |
| Integrative, dynamic structural biology at atomic resolution - it's about time H van den Bedem, JS Fraser Nature methods 12 (4), 307-318, 2015 | 251 | 2015 |
| Ig-like domains on bacteriophages: a tale of promiscuity and deceit JS Fraser, Z Yu, KL Maxwell, AR Davidson Journal of molecular biology 359 (2), 496-507, 2006 | 232 | 2006 |
| CryptoSite: expanding the druggable proteome by characterization and prediction of cryptic binding sites P Cimermancic, P Weinkam, TJ Rettenmaier, L Bichmann, DA Keedy, ... Journal of molecular biology 428 (4), 709-719, 2016 | 211 | 2016 |
| Preprints for the life sciences JM Berg, N Bhalla, PE Bourne, M Chalfie, DG Drubin, JS Fraser, ... Science 352 (6288), 899-901, 2016 | 202 | 2016 |
| Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography DA Keedy, LR Kenner, M Warkentin, RA Woldeyes, JB Hopkins, ... Elife 4, e07574, 2015 | 188 | 2015 |
| Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR RB Fenwick, H van den Bedem, JS Fraser, PE Wright Proceedings of the National Academy of Sciences 111 (4), E445-E454, 2014 | 183 | 2014 |
| Automated electron‐density sampling reveals widespread conformational polymorphism in proteins PT Lang, HL Ng, JS Fraser, JE Corn, N Echols, M Sales, JM Holton, ... Protein Science 19 (7), 1420-1431, 2010 | 172 | 2010 |
| From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II H Braberg, H Jin, EA Moehle, YA Chan, S Wang, M Shales, JJ Benschop, ... Cell 154 (4), 775-788, 2013 | 171 | 2013 |
| An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering DA Keedy, ZB Hill, JT Biel, E Kang, TJ Rettenmaier, J Brandao-Neto, ... Elife 7, e36307, 2018 | 160 | 2018 |
Henry van den BedemSVP ML Research & Cheminformatics, Atomwise Inc. and Dept of BTS, UCSFVerified email at ucsf.edu
