| High basal γH2AX levels sustain self-renewal of mouse embryonic and induced pluripotent stem cells V Turinetto, L Orlando, Y Sanchez-Ripoll, B Kumpfmueller, MP Storm, ... stem cells 30 (7), 1414-1423, 2012 | 95 | 2012 |
| A rapid flow cytometry test based on histone H2AX phosphorylation for the sensitive and specific diagnosis of ataxia telangiectasia P Porcedda, V Turinetto, A Brusco, S Cavalieri, E Lantelme, L Orlando, ... Cytometry Part A: The Journal of the International Society for Analytical …, 2008 | 73 | 2008 |
| Induced pluripotent stem cells: advances in the quest for genetic stability during reprogramming process V Turinetto, L Orlando, C Giachino International journal of molecular sciences 18 (9), 1952, 2017 | 68 | 2017 |
| Sam68 allows selective targeting of human cancer stem cells YD Benoit, RR Mitchell, RM Risueño, L Orlando, B Tanasijevic, AL Boyd, ... Cell Chemical Biology 24 (7), 833-844. e9, 2017 | 51 | 2017 |
| Fluorescent Silica Nanoparticles Improve Optical Imaging of Stem Cells Allowing Direct Discrimination between Live and Early‐Stage Apoptotic Cells L Accomasso, EC Rocchietti, S Raimondo, F Catalano, G Alberto, ... Small 8 (20), 3192-200, 2012 | 47 | 2012 |
| Human pluripotency is initiated and preserved by a unique subset of founder cells M Nakanishi, RR Mitchell, YD Benoit, L Orlando, JC Reid, K Shimada, ... Cell 177 (4), 910-924. e22, 2019 | 44 | 2019 |
| Maintenance of genomic stability in mouse embryonic stem cells: relevance in aging and disease C Giachino, L Orlando, V Turinetto International Journal of Molecular Sciences 14 (2), 2617-2636, 2013 | 35 | 2013 |
| Brief report: human acute myeloid leukemia reprogramming to pluripotency is a rare event and selects for patient hematopoietic cells devoid of leukemic mutations JH Lee, KR Salci, JC Reid, L Orlando, B Tanasijevic, Z Shapovalova, ... Stem Cells 35 (9), 2095-2102, 2017 | 34 | 2017 |
| The cyclin-dependent kinase inhibitor 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole induces nongenotoxic, DNA replication-independent apoptosis of normal and leukemic cells … V Turinetto, P Porcedda, L Orlando, M De Marchi, A Amoroso, C Giachino BMC cancer 9, 1-13, 2009 | 25 | 2009 |
| Two-tier analysis of histone H2AX phosphorylation allows the identification of Ataxia Telangiectasia heterozygotes P Porcedda, V Turinetto, L Orlando, E Lantelme, A Brusco, M De Marchi, ... Radiotherapy and Oncology 92 (1), 133-137, 2009 | 25 | 2009 |
| An in vitro model of T cell receptor revision in mature human CD8+ T cells E Lantelme, L Orlando, P Porcedda, V Turinetto, M De Marchi, A Amoroso, ... Molecular immunology 45 (2), 328-337, 2008 | 24 | 2008 |
| Expression of IFNγR2 mutated in a dileucine internalization motif reinstates IFNγ signaling and apoptosis in human T lymphocytes D Boselli, J Ragimbeau, L Orlando, P Cappello, M Capello, C Ambrogio, ... Immunology letters 134 (1), 17-25, 2010 | 22 | 2010 |
| Phosphorylation state of the histone variant H2A. X controls human stem and progenitor cell fate decisions L Orlando, B Tanasijevic, M Nakanishi, JC Reid, JL García-Rodríguez, ... Cell Reports 34 (10), 2021 | 20 | 2021 |
| Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics YD Benoit, RR Mitchell, W Wang, L Orlando, AL Boyd, B Tanasijevic, ... Cell chemical biology 28 (10), 1394-1406. e10, 2021 | 18 | 2021 |
| Involvement of MRE11A and XPA gene polymorphisms in the modulation of DNA double-strand break repair activity: A genotype–phenotype correlation study F Ricceri, P Porcedda, A Allione, V Turinetto, S Polidoro, S Guarrera, ... DNA repair 10 (10), 1044-1050, 2011 | 16 | 2011 |
| Differential coupling of self-renewal signaling pathways in murine induced pluripotent stem cells L Orlando, Y Sanchez-Ripoll, J Foster, H Bone, C Giachino, MJ Welham PLoS One 7 (1), e30234, 2012 | 13 | 2012 |
| A novel defect in mitochondrial p53 accumulation following DNA damage confers apoptosis resistance in Ataxia Telangiectasia and Nijmegen Breakage Syndrome T-cells V Turinetto, P Porcedda, V Minieri, L Orlando, E Lantelme, L Accomasso, ... DNA repair 9 (11), 1200-1208, 2010 | 11 | 2010 |
| Acquisition of pluripotency through continued environmental influence on OCT4-induced plastic human fibroblasts KR Salci, JB Lee, RR Mitchell, L Orlando, A Fiebig-Comyn, ... Stem Cell Research 15 (1), 221-230, 2015 | 7 | 2015 |
| Chemical genomics reveals targetable programs of human cancers rooted in pluripotency L Orlando, YD Benoit, JC Reid, M Nakanishi, AL Boyd, ... Cell chemical biology 30 (7), 780-794. e8, 2023 | 6 | 2023 |
| Human pluripotent stem cells identify molecular targets of trisomy 12 in chronic lymphocytic leukemia patients JC Reid, D Golubeva, AL Boyd, CG Hollands, C Henly, L Orlando, ... Cell Reports 34 (11), 2021 | 6 | 2021 |
Claudia GiachinoUniversity of Turin, ItalyVerified email at unito.it