| Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase J Du, Y Zhou, X Su, JJ Yu, S Khan, H Jiang, J Kim, J Woo, JH Kim, ... Science 334 (6057), 806-809, 2011 | 1484 | 2011 |
| SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine H Jiang, S Khan, Y Wang, G Charron, B He, C Sebastian, J Du, R Kim, ... Nature 496 (7443), 110-113, 2013 | 780 | 2013 |
| A SIRT2-selective inhibitor promotes c-Myc oncoprotein degradation and exhibits broad anticancer activity H Jing, J Hu, B He, YLN Abril, J Stupinski, K Weiser, M Carbonaro, ... Cancer cell 29 (3), 297-310, 2016 | 282 | 2016 |
| Protein lysine acylation and cysteine succination by intermediates of energy metabolism H Lin, X Su, B He ACS chemical biology 7 (6), 947-960, 2012 | 249 | 2012 |
| Identification of a cellularly active SIRT6 allosteric activator Z Huang, J Zhao, W Deng, Y Chen, J Shang, K Song, L Zhang, C Wang, ... Nature chemical biology 14 (12), 1118-1126, 2018 | 236 | 2018 |
| Catalytic asymmetric cyanosilylation of ketones by a chiral amino acid salt X Liu, B Qin, X Zhou, B He, X Feng Journal of the American Chemical Society 127 (35), 12224-12225, 2005 | 208 | 2005 |
| Efficient Demyristoylase Activity of SIRT2 Revealed by Kinetic and Structural Studies YB Teng, H Jing, P Aramsangtienchai, B He, S Khan, J Hu, H Lin, Q Hao Scientific Reports 5, 5(8529), 1-8., 2015 | 185 | 2015 |
| Metabolic Characterization of a Sirt5 deficient mouse model J Yu, S Sadhukhan, LG Noriega, N Moullan, B He, RS Weiss, H Lin, ... Scientific Reports 11, (32), 5213-5216., 2013 | 144 | 2013 |
| Highly Enantioselective Cyanosilylation of aldehydes catalyzed by novel β-amino alcohol− titanium complexes Y Li, B He, B Qin, X Feng, G Zhang The Journal of organic chemistry 69 (23), 7910-7913, 2004 | 117 | 2004 |
| HDAC8 catalyzes the hydrolysis of long chain fatty acyl lysine P Aramsangtienchai, NA Spiegelman, B He, SP Miller, L Dai, Y Zhao, ... ACS chemical biology 11 (10), 2685-2692, 2016 | 108 | 2016 |
| Thiosuccinyl peptides as Sirt5-specific inhibitors B He, J Du, H Lin Journal of the American Chemical Society 134 (4), 1922-1925, 2012 | 104 | 2012 |
| The bicyclic intermediate structure provides insights into the desuccinylation mechanism of human sirtuin 5 (SIRT5) Y Zhou, H Zhang, B He, J Du, H Lin, RA Cerione, Q Hao Journal of Biological Chemistry 287 (34), 28307-28314, 2012 | 96 | 2012 |
| SIRT2 reverses 4-oxononanoyl lysine modification on histones J Jin, B He, X Zhang, H Lin, Y Wang Journal of the American Chemical Society 138 (38), 12304-12307, 2016 | 86 | 2016 |
| Thiomyristoyl peptides as cell-permeable Sirt6 inhibitors B He, J Hu, X Zhang, H Lin Organic & Biomolecular Chemistry 12 (38), 7498-502, 2014 | 85 | 2014 |
| Total synthesis of (−)-ardeemin B He, H Song, Y Du, Y Qin The Journal of Organic Chemistry 74 (1), 298-304, 2009 | 82 | 2009 |
| Romidepsin induces G2/M phase arrest via Erk/cdc25C/cdc2/cyclinB pathway and apoptosis induction through JNK/c-Jun/caspase3 pathway in hepatocellular carcinoma cells WJ Sun, H Huang, B He, DH Hu, PH Li, YJ Yu, XH Zhou, Z Lv, L Zhou, ... Biochemical pharmacology 127, 90-100, 2017 | 80 | 2017 |
| A fluorogenic assay for screening Sirt6 modulators J Hu, B He, S Bhargava, H Lin Organic & biomolecular chemistry 11 (32), 5213-5216, 2013 | 60 | 2013 |
| Zinc-dependent deacetylase (HDAC) inhibitors with different zinc binding groups Y Li, F Wang, X Chen, J Wang, Y Zhao, Y Li, B He Current topics in medicinal chemistry 19 (3), 223-241, 2019 | 59 | 2019 |
| Pharmacological and genetic perturbation establish SIRT5 as a promising target in breast cancer YLN Abril, IR Fernandez, JY Hong, YL Chiang, DA Kutateladze, Q Zhao, ... Oncogene 40 (9), 1644-1658, 2021 | 57 | 2021 |
| SIRT4 is the last puzzle of mitochondrial sirtuins Y Li, Y Zhou, F Wang, X Chen, C Wang, J Wang, T Liu, Y Li, B He Bioorganic & medicinal chemistry 26 (14), 3861-3865, 2018 | 57 | 2018 |