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Dennis Kostka
Dennis Kostka
Verified email at pitt.edu - Homepage
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Cited by
Year
A high-resolution map of human evolutionary constraint using 29 mammals
K Lindblad-Toh, M Garber, O Zuk, MF Lin, BJ Parker, S Washietl, ...
Nature 478 (7370), 476-482, 2011
12832011
Regulatory networks define phenotypic classes of human stem cell lines
FJ Müller, LC Laurent, D Kostka, I Ulitsky, R Williams, C Lu, IH Park, ...
Nature 455 (7211), 401-405, 2008
4002008
Gibbon genome and the fast karyotype evolution of small apes
L Carbone, R Alan Harris, S Gnerre, KR Veeramah, B Lorente-Galdos, ...
Nature 513 (7517), 195-201, 2014
3862014
scds: Computational annotation of doublets in single-cell RNA sequencing data
AS Bais, D Kostka
Bioinformatics 36 (4), btz968, 2019
2422019
The complex genetics of hypoplastic left heart syndrome
X Liu, H Yagi, S Saeed, AS Bais, GC Gabriel, Z Chen, KA Peterson, Y Li, ...
Nature genetics 49 (7), 1152-1159, 2017
2262017
Integrating diverse datasets improves developmental enhancer prediction
GD Erwin, N Oksenberg, RM Truty, D Kostka, KK Murphy, N Ahituv, ...
PLoS computational biology 10 (6), e1003677, 2014
1882014
Finding disease specific alterations in the co-expression of genes
D Kostka, R Spang
Bioinformatics 20 (suppl_1), i194-i199, 2004
1882004
Nested effects models for high-dimensional phenotyping screens
F Markowetz, D Kostka, OG Troyanskaya, R Spang
Bioinformatics 23 (13), i305-i312, 2007
1302007
The role of GC-biased gene conversion in shaping the fastest evolving regions of the human genome
D Kostka, MJ Hubisz, A Siepel, KS Pollard
Molecular biology and evolution 29 (3), 1047-1057, 2012
1132012
Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment
H Liu, CH Zhang, N Ammanamanchi, S Suresh, C Lewarchik, K Rao, ...
Science translational medicine 11 (513), eaaw6419, 2019
972019
MicroRNA-17~ 92 is required for nephrogenesis and renal function
AK Marrone, DB Stolz, SI Bastacky, D Kostka, AJ Bodnar, J Ho
Journal of the American Society of Nephrology 25 (7), 1440-1452, 2014
872014
DAF-16 and TCER-1 Facilitate Adaptation to Germline Loss by Restoring Lipid Homeostasis and Repressing Reproductive Physiology in C. elegans
FRG Amrit, EM Steenkiste, R Ratnappan, SW Chen, TB McClendon, ...
PLoS genetics 12 (2), e1005788, 2016
822016
A model-based analysis of GC-biased gene conversion in the human and chimpanzee genomes
JA Capra, MJ Hubisz, D Kostka, KS Pollard, A Siepel
PLoS genetics 9 (8), e1003684, 2013
822013
The importance of being cis: evolution of orthologous fish and mammalian enhancer activity
DI Ritter, Q Li, D Kostka, KS Pollard, S Guo, JH Chuang
Molecular biology and evolution 27 (10), 2322-2332, 2010
652010
Expression of late cell cycle genes and an increased proliferative capacity characterize very early relapse of childhood acute lymphoblastic leukemia
R Kirschner-Schwabe, C Lottaz, J Tödling, P Rhein, L Karawajew, ...
Clinical cancer research 12 (15), 4553-4561, 2006
612006
Genome-wide enhancer annotations differ significantly in genomic distribution, evolution, and function
ML Benton, SC Talipineni, D Kostka, JA Capra
Bmc Genomics 20, 1-22, 2019
582019
Random forest based similarity learning for single cell RNA sequencing data
MB Pouyan, D Kostka
Bioinformatics, 34 (13), i79–i88, 2018
572018
Uncompensated mitochondrial oxidative stress underlies heart failure in an iPSC-derived model of congenital heart disease
X Xu, K Jin, AS Bais, W Zhu, H Yagi, TN Feinstein, PK Nguyen, ...
Cell Stem Cell, 2022
542022
Single-cell transcriptomic analysis identifies murine heart molecular features at embryonic and neonatal stages
W Feng, A Bais, H He, C Rios, S Jiang, J Xu, C Chang, D Kostka, G Li
Nature Communications 13 (1), 7960, 2022
462022
Computational profiling of hiPSC-derived heart organoids reveals chamber defects associated with NKX2-5 deficiency
W Feng, H Schriever, S Jiang, A Bais, H Wu, D Kostka, G Li
Communications Biology 5 (1), 399, 2022
452022
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