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The UK10K project identifies rare variants in health and disease

Statistics group Ciampi Antonio 8 Greenwood Celia MT (co-chair) 7 8 14 19 ...

Nature 526 (7571), 82-90, 2015

Mandates: UK Biotechnology and Biological Sciences Research Council, British Heart …

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

V Turcot, Y Lu, HM Highland, C Schurmann, AE Justice, RS Fine, ...

Nature genetics 50 (1), 26-41, 2018

Mandates: Swiss National Science Foundation, US National Institutes of Health …

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Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset

M Swami, AE Hendricks, T Gillis, T Massood, J Mysore, RH Myers, ...

Human molecular genetics 18 (16), 3039-3047, 2009

Mandates: US National Institutes of Health

Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes

E Dragileva, A Hendricks, A Teed, T Gillis, ET Lopez, EC Friedberg, ...

Neurobiology of disease 33 (1), 37-47, 2009

Mandates: US National Institutes of Health

KSR2 mutations are associated with obesity, insulin resistance, and impaired cellular fuel oxidation

LR Pearce, N Atanassova, MC Banton, B Bottomley, AA van der Klaauw, ...

Cell 155 (4), 765-777, 2013

Mandates: Cancer Research UK, UK Medical Research Council, Wellcome Trust, UK Research …

Whole-genome sequencing coupled to imputation discovers genetic signals for anthropometric traits

I Tachmazidou, D Süveges, JL Min, GRS Ritchie, J Steinberg, K Walter, ...

The American Journal of Human Genetics 100 (6), 865-884, 2017

Mandates: US National Institutes of Health, Academy of Finland, Versus Arthritis, UK …

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Body mass index is negatively associated with telomere length: a collaborative cross-sectional meta-analysis of 87 observational studies

M Gielen, GJ Hageman, EE Antoniou, K Nordfjall, M Mangino, ...

The American journal of clinical nutrition 108 (3), 453-475, 2018

Mandates: US National Institutes of Health, Canadian Institutes of Health Research …

Haplotypes and gene expression implicate the MAPT region for Parkinson disease: The GenePD Study

JE Tobin, JC Latourelle, MF Lew, C Klein, O Suchowersky, HA Shill, ...

Neurology 71 (1), 28-34, 2008

Mandates: US National Institutes of Health

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Genetic architecture of human thinness compared to severe obesity

F Riveros-McKay, V Mistry, R Bounds, A Hendricks, JM Keogh, H Thomas, ...

PLoS genetics 15 (1), e1007603, 2019

Mandates: US National Institutes of Health, UK Economic and Social Research Council …

[PDF] springer.com

The Gly2019Ser mutation in LRRK2is not fully penetrant in familial Parkinson's disease: the GenePD study

JC Latourelle, M Sun, MF Lew, O Suchowersky, C Klein, LI Golbe, ...

BMC medicine 6, 1-7, 2008

Mandates: US National Institutes of Health

Human semaphorin 3 variants link melanocortin circuit development and energy balance

AA Van Der Klaauw, S Croizier, EM De Oliveira, LKJ Stadler, S Park, ...

Cell 176 (4), 729-742. e18, 2019

Mandates: US National Institutes of Health, British Heart Foundation, Cancer Research …

[HTML] mdpi.com

Iron in micronutrient powder promotes an unfavorable gut microbiota in Kenyan infants

M Tang, DN Frank, AE Hendricks, D Ir, F Esamai, E Liechty, ...

Nutrients 9 (7), 776, 2017

Mandates: US National Institutes of Health

Assessment of cortical and striatal involvement in 523 Huntington disease brains

TC Hadzi, AE Hendricks, JC Latourelle, KL Lunetta, LA Cupples, T Gillis, ...

Neurology 79 (16), 1708-1715, 2012

Mandates: US National Institutes of Health, Howard Hughes Medical Institute

Estimating the probability of de novo HD cases from transmissions of expanded penetrant CAG alleles in the Huntington disease gene from male carriers of high normal alleles (27 …

AE Hendricks, JC Latourelle, KL Lunetta, LA Cupples, V Wheeler, ...

American Journal of Medical Genetics Part A 149 (7), 1375-1381, 2009

Mandates: US National Institutes of Health

Rare variant analysis of human and rodent obesity genes in individuals with severe childhood obesity

AE Hendricks, EG Bochukova, G Marenne, JM Keogh, N Atanassova, ...

Scientific reports 7 (1), 4394, 2017

Mandates: US National Institutes of Health, German Research Foundation, British Heart …

[HTML] nature.com

Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis

Y Yang, AA van der Klaauw, L Zhu, TM Cacciottolo, Y He, LKJ Stadler, ...

Nature communications 10 (1), 1718, 2019

Mandates: US National Institutes of Health, US Department of Agriculture, American …

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Genetic associations with expression for genes implicated in GWAS studies for atherosclerotic cardiovascular disease and blood phenotypes

X Zhang, AD Johnson, AE Hendricks, SJ Hwang, K Tanriverdi, ...

Human molecular genetics 23 (3), 782-795, 2014

Mandates: US National Institutes of Health

Exome sequencing identifies genes and gene sets contributing to severe childhood obesity, linking PHIP variants to repressed POMC transcription

G Marenne, AE Hendricks, A Perdikari, R Bounds, F Payne, JM Keogh, ...

Cell Metabolism 31 (6), 1107-1119. e12, 2020

Mandates: Swiss National Science Foundation, US National Institutes of Health, British …

Correction for multiple testing in a gene region

AE Hendricks, J Dupuis, MW Logue, RH Myers, KL Lunetta

European Journal of Human Genetics 22 (3), 414-418, 2014

Mandates: US National Institutes of Health