| Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers IB Hilton, AM D'ippolito, CM Vockley, PI Thakore, GE Crawford, TE Reddy, ... Nature biotechnology 33 (5), 510-517, 2015 | 2222 | 2015 |
| RNA-guided gene activation by CRISPR-Cas9–based transcription factors P Perez-Pinera, DD Kocak, CM Vockley, AF Adler, AM Kabadi, ... Nature methods 10 (10), 973-976, 2013 | 1733 | 2013 |
| Expanded encyclopaedias of DNA elements in the human and mouse genomes JE Moore, MJ Purcaro, HE Pratt, CB Epstein, N Shoresh, J Adrian, T Kawli, ... Nature 583 (7818), 699-710, 2020 | 1584 | 2020 |
| Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome CM Vockley, AM D’Ippolito, IC McDowell, WH Majoros, A Safi, L Song, ... Cell 166 (5), 1269-1281. e19, 2016 | 193 | 2016 |
| Clustering gene expression time series data using an infinite Gaussian process mixture model IC McDowell, D Manandhar, CM Vockley, AK Schmid, TE Reddy, ... PLoS computational biology 14 (1), e1005896, 2018 | 179 | 2018 |
| Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum CL Frank, F Liu, R Wijayatunge, L Song, MT Biegler, MG Yang, ... Nature neuroscience 18 (5), 647-656, 2015 | 171 | 2015 |
| Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE-and CRISPR/Cas9-based transcriptional activators LR Polstein, P Perez-Pinera, DD Kocak, CM Vockley, P Bledsoe, L Song, ... Genome research 25 (8), 1158-1169, 2015 | 166 | 2015 |
| Massively parallel quantification of the regulatory effects of noncoding genetic variation in a human cohort CM Vockley, C Guo, WH Majoros, M Nodzenski, DM Scholtens, ... Genome research 25 (8), 1206-1214, 2015 | 130 | 2015 |
| Genome-wide quantification of the effects of DNA methylation on human gene regulation AJ Lea, CM Vockley, RA Johnston, CA Del Carpio, LB Barreiro, TE Reddy, ... eLife 7, e37513, 2018 | 123 | 2018 |
| Glucocorticoid receptor recruits to enhancers and drives activation by motif-directed binding IC McDowell, A Barrera, AM D'Ippolito, CM Vockley, LK Hong, ... Genome research 28 (9), 1272-1284, 2018 | 113 | 2018 |
| Pre-established chromatin interactions mediate the genomic response to glucocorticoids AM D'Ippolito, IC McDowell, A Barrera, LK Hong, SM Leichter, LC Bartelt, ... Cell systems 7 (2), 146-160. e7, 2018 | 104 | 2018 |
| Evidence for multiple roles for grainyheadlike 2 in the establishment and maintenance of human mucociliary airway epithelium X Gao, CM Vockley, F Pauli, KM Newberry, Y Xue, SH Randell, TE Reddy, ... Proceedings of the National Academy of Sciences 110 (23), 9356-9361, 2013 | 98 | 2013 |
| Perspectives on ENCODE MP Snyder, TR Gingeras, JE Moore, Z Weng, MB Gerstein, B Ren, ... Nature 583 (7818), 693-698, 2020 | 97 | 2020 |
| Detection and characterization of silencers and enhancer-blockers in the greater CFTR locus HM Petrykowska, CM Vockley, L Elnitski Genome research 18 (8), 1238-1246, 2008 | 86 | 2008 |
| Enhanced MyoD-induced transdifferentiation to a myogenic lineage by fusion to a potent transactivation domain AM Kabadi, PI Thakore, CM Vockley, DG Ousterout, TM Gibson, F Guilak, ... ACS synthetic biology 4 (6), 689-699, 2015 | 53 | 2015 |
| Human genome-wide measurement of drug-responsive regulatory activity GD Johnson, A Barrera, IC McDowell, AM D’Ippolito, WH Majoros, ... Nature Communications 9 (1), 1-9, 2018 | 46 | 2018 |
| Decoding the role of regulatory element polymorphisms in complex disease CM Vockley, A Barrera, TE Reddy Current Opinion in Genetics & Development 43, 38-45, 2017 | 36 | 2017 |
| Congenital anemia reveals distinct targeting mechanisms for master transcription factor GATA1 LS Ludwig, CA Lareau, EL Bao, N Liu, T Utsugisawa, AM Tseng, ... Blood, The Journal of the American Society of Hematology 139 (16), 2534-2546, 2022 | 28 | 2022 |
| A long-range flexible billboard model of gene activation CM Vockley, IC McDowell, AM D'Ippolito, TE Reddy Transcription 8 (4), 261-267, 2017 | 19 | 2017 |
| Increased genetic diversity and intersubtype recombinants of HIV-1 in blood donors from urban Cameroon A Machuca, S Tang, J Hu, S Lee, O Wood, C Vockley, SG Vutukuri, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 45 (3), 361-363, 2007 | 18 | 2007 |
Timothy E ReddyAssociate Professor, Duke UniversityVerified email at duke.edu