| COVID-19: drug targets and potential treatments C Gil, T Ginex, I Maestro, V Nozal, L Barrado-Gil, MÁ Cuesta-Geijo, ... Journal of medicinal chemistry 63 (21), 12359-12386, 2020 | 456 | 2020 |
| Tacrine–melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties MI Fernández‐Bachiller, C Pérez, NE Campillo, JA Páez, ... ChemMedChem: Chemistry Enabling Drug Discovery 4 (5), 828-841, 2009 | 203 | 2009 |
| Plant-based heterologous expression of Mal d 2, a thaumatin-like protein and allergen of apple (Malus domestica), and its characterization as an antifungal protein M Krebitz, B Wagner, F Ferreira, C Peterbauer, N Campillo, M Witty, ... Journal of molecular biology 329 (4), 721-730, 2003 | 180 | 2003 |
| Homology models of the cannabinoid CB1 and CB2 receptors. A docking analysis study C Montero, NE Campillo, P Goya, JA Páez European journal of medicinal chemistry 40 (1), 75-83, 2005 | 144 | 2005 |
| Directed mutagenesis alters the stereochemistry of catalysis by isolated ketoreductase domains from the erythromycin polyketide synthase A Baerga-Ortiz, B Popovic, AP Siskos, HM O'Hare, D Spiteller, ... Chemistry & biology 13 (3), 277-285, 2006 | 126 | 2006 |
| Exploring the binding sites of glycogen synthase kinase 3. Identification and characterization of allosteric modulation cavities V Palomo, I Soteras, DI Perez, C Perez, C Gil, NE Campillo, A Martinez Journal of medicinal chemistry 54 (24), 8461-8470, 2011 | 125 | 2011 |
| Tau-centric multitarget approach for Alzheimer’s disease: development of first-in-class dual glycogen synthase kinase 3β and tau-aggregation inhibitors A Gandini, M Bartolini, D Tedesco, L Martinez-Gonzalez, C Roca, ... Journal of medicinal chemistry 61 (17), 7640-7656, 2018 | 114 | 2018 |
| 5-imino-1, 2, 4-thiadiazoles: first small molecules as substrate competitive inhibitors of glycogen synthase kinase 3 V Palomo, DI Perez, C Perez, JA Morales-Garcia, I Soteras, S Alonso-Gil, ... Journal of Medicinal Chemistry 55 (4), 1645-1661, 2012 | 102 | 2012 |
| Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model M Redondo, JG Zarruk, P Ceballos, DI Pérez, C Pérez, A Perez-Castillo, ... European journal of medicinal chemistry 47, 175-185, 2012 | 92 | 2012 |
| Crystal structure of CbpF, a bifunctional choline‐binding protein and autolysis regulator from Streptococcus pneumoniae R Molina, A González, M Stelter, I Pérez‐Dorado, R Kahn, M Morales, ... EMBO reports 10 (3), 246-251, 2009 | 85 | 2009 |
| Plasma and peritoneal fluid population pharmacokinetics of micafungin in post-surgical patients with severe peritonitis S Grau, S Luque, N Campillo, E Samsó, U Rodríguez, CA García-Bernedo, ... Journal of Antimicrobial Chemotherapy 70 (10), 2854-2861, 2015 | 84 | 2015 |
| Elucidation of the molecular recognition of bacterial cell wall by modular pneumococcal phage endolysin CPL-1 I Perez-Dorado, NE Campillo, B Monterroso, D Hesek, M Lee, JA Paez, ... Journal of Biological Chemistry 282 (34), 24990-24999, 2007 | 83 | 2007 |
| Synthesis, structural analysis, and biological evaluation of thioxoquinazoline derivatives as phosphodiesterase 7 inhibitors T Castaño, H Wang, NE Campillo, S Ballester, C González‐García, ... ChemMedChem: Chemistry Enabling Drug Discovery 4 (5), 866-876, 2009 | 79 | 2009 |
| Hybridizing feature selection and feature learning approaches in QSAR modeling for drug discovery I Ponzoni, V Sebastián-Pérez, C Requena-Triguero, C Roca, MJ Martínez, ... Scientific reports 7 (1), 2403, 2017 | 76 | 2017 |
| Subtly modulating glycogen synthase kinase 3 β: allosteric inhibitor development and their potential for the treatment of chronic diseases V Palomo, DI Perez, C Roca, C Anderson, N Rodríguez-Muela, C Perez, ... Journal of medicinal chemistry 60 (12), 4983-5001, 2017 | 75 | 2017 |
| Chagas disease: progress and new perspectives F Sanchez-Sancho, NE Campillo, JA Páez Current Medicinal Chemistry 17 (5), 423-452, 2010 | 74 | 2010 |
| p‐Coumaric acid decarboxylase from Lactobacillus plantarum: Structural insights into the active site and decarboxylation catalytic mechanism H Rodríguez, I Angulo, B de Las Rivas, N Campillo, JA Páez, R Muñoz, ... Proteins: Structure, Function, and Bioinformatics 78 (7), 1662-1676, 2010 | 73 | 2010 |
| Artificial neural networks in ADMET modeling: prediction of blood–brain barrier permeation A Guerra, JA Páez, NE Campillo QSAR & Combinatorial Science 27 (5), 586-594, 2008 | 72 | 2008 |
| Colistin for the treatment of urinary tract infections caused by extremely drug-resistant Pseudomonas aeruginosa: dose is critical L Sorlí, S Luque, J Li, N Campillo, M Danés, M Montero, C Segura, S Grau, ... Journal of Infection 79 (3), 253-261, 2019 | 70 | 2019 |
| Validation of a colistin plasma concentration breakpoint as a predictor of nephrotoxicity in patients treated with colistin methanesulfonate JP Horcajada, L Sorlí, S Luque, N Benito, C Segura, N Campillo, ... International journal of antimicrobial agents 48 (6), 725-727, 2016 | 68 | 2016 |
