| Installing hydrolytic activity into a completely de novo protein framework AJ Burton, AR Thomson, WM Dawson, RL Brady, DN Woolfson Nature chemistry 8 (9), 837-844, 2016 | 209 | 2016 |
| Unraveling the role of protein dynamics in dihydrofolate reductase catalysis LYP Luk, J Javier Ruiz-Pernia, WM Dawson, M Roca, EJ Loveridge, ... Proceedings of the National Academy of Sciences 110 (41), 16344-16349, 2013 | 149 | 2013 |
| Constructing ion channels from water-soluble α-helical barrels AJ Scott, A Niitsu, HT Kratochvil, EJM Lang, JT Sengel, WM Dawson, ... Nature chemistry 13 (7), 643-650, 2021 | 86 | 2021 |
| De Novo-Designed α-Helical Barrels as Receptors for Small Molecules F Thomas, WM Dawson, EJM Lang, AJ Burton, GJ Bartlett, GG Rhys, ... ACS Synthetic Biology 7 (7), 1808-1816, 2018 | 80 | 2018 |
| Towards functional de novo designed proteins WM Dawson, GG Rhys, DN Woolfson Current Opinion in Chemical Biology 52, 102-111, 2019 | 79 | 2019 |
| Decorating self-assembled peptide cages with proteins JF Ross, A Bridges, JM Fletcher, D Shoemark, D Alibhai, HEV Bray, ... ACS nano 11 (8), 7901-7914, 2017 | 65 | 2017 |
| Coiled coils 9-to-5: rational de novo design of α-helical barrels with tunable oligomeric states WM Dawson, FJO Martin, GG Rhys, KL Shelley, RL Brady, DN Woolfson Chemical Science 12 (20), 6923-6928, 2021 | 53 | 2021 |
| The role of large-scale motions in catalysis by dihydrofolate reductase EJ Loveridge, LH Tey, EM Behiry, WM Dawson, RM Evans, ... Journal of the American Chemical Society 133 (50), 20561-20570, 2011 | 50 | 2011 |
| Protein Isotope Effects in Dihydrofolate Reductase From Geobacillus stearothermophilus Show Entropic–Enthalpic Compensatory Effects on the Rate Constant LYP Luk, JJ Ruiz-Pernía, WM Dawson, EJ Loveridge, I Tuñón, V Moliner, ... Journal of the American Chemical Society 136 (49), 17317-17323, 2014 | 40 | 2014 |
| A Versatile Disulfide-Driven Recycling System for NADP+ with High Cofactor Turnover Number A Angelastro, WM Dawson, LYP Luk, RK Allemann ACS Catalysis 7 (2), 1025-1029, 2017 | 36 | 2017 |
| NDP52 acts as a redox sensor in PINK1/Parkin‐mediated mitophagy T Kataura, EG Otten, Y Rabanal‐Ruiz, E Adriaenssens, F Urselli, F Scialo, ... The EMBO Journal 42 (5), e111372, 2023 | 29 | 2023 |
| Structural resolution of switchable states of a de novo peptide assembly WM Dawson, EJM Lang, GG Rhys, KL Shelley, C Williams, RL Brady, ... Nature Communications 12 (1), 1530, 2021 | 29 | 2021 |
| De novo designed peptides for cellular delivery and subcellular localisation GG Rhys, JA Cross, WM Dawson, HF Thompson, S Shanmugaratnam, ... Nature Chemical Biology 18 (9), 999-1004, 2022 | 27 | 2022 |
| Differential sensing with arrays of de novo designed peptide assemblies WM Dawson, KL Shelley, JM Fletcher, DA Scott, L Lombardi, GG Rhys, ... Nature Communications 14 (1), 383, 2023 | 16 | 2023 |
| How coiled-coil assemblies accommodate multiple aromatic residues GG Rhys, WM Dawson, JL Beesley, FJO Martin, RL Brady, AR Thomson, ... Biomacromolecules 22 (5), 2010-2019, 2021 | 11 | 2021 |
| Rationally seeded computational protein design of ɑ-helical barrels KI Albanese, R Petrenas, F Pirro, EA Naudin, U Borucu, WM Dawson, ... Nature Chemical Biology, 1-9, 2024 | 5 | 2024 |
| Chemoenzymatic assembly of isotopically labeled folates A Angelastro, WM Dawson, LYP Luk, EJ Loveridge, RK Allemann Journal of the American Chemical Society 139 (37), 13047-13054, 2017 | 4 | 2017 |
| CC+: A searchable database of validated coiled coils in PDB structures and AlphaFold2 models P Kumar, R Petrenas, WM Dawson, H Schweke, ED Levy, DN Woolfson Protein science 32 (11), e4789, 2023 | 3 | 2023 |
| Reduced Susceptibility of Moritella profunda Dihydrofolate Reductase to Trimethoprim is Not Due to Glutamate 28 EJ Loveridge, WM Dawson, RM Evans, A Sobolewska, RK Allemann The Protein Journal 30, 546-548, 2011 | 3 | 2011 |
| Aliphatic 1H, 13C and 15N chemical shift assignments of dihydrofolate reductase from the psychropiezophile Moritella profunda in complex with NADP+ and folate EJ Loveridge, SM Matthews, C Williams, SBM Whittaker, UL Günther, ... Biomolecular NMR assignments 7, 61-64, 2013 | 2 | 2013 |
Guto G RhysLecturer in Chemical Biology, Cardiff University (UK)Verified email at cardiff.ac.uk
