Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model S Fong, E Teo, LF Ng, CB Chen, LN Lakshmanan, SY Tsoi, PK Moore, ... Scientific reports 6 (1), 33781, 2016 | 107 | 2016 |
Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function JS Hawe, R Wilson, KT Schmid, L Zhou, LN Lakshmanan, BC Lehne, ... Nature genetics 54 (1), 18-29, 2022 | 97 | 2022 |
Clonal expansion of mitochondrial DNA deletions is a private mechanism of ageing in long-lived animals LN Lakshmanan, Z Yee, LF Ng, R Gunawan, B Halliwell, J Gruber Aging Cell, 2018 | 46 | 2018 |
Is mitochondrial DNA turnover slower than commonly assumed? SK Poovathingal, J Gruber, LN Lakshmanan, B Halliwell, R Gunawan Biogerontology 13, 557-564, 2012 | 35 | 2012 |
Role of direct repeat and stem-loop motifs in mtDNA deletions: cause or coincidence? LN Lakshmanan, J Gruber, B Halliwell, R Gunawan PLoS One 7 (4), e35271, 2012 | 23 | 2012 |
Are mutagenic non D-loop direct repeat motifs in mitochondrial DNA under a negative selection pressure? LN Lakshmanan, J Gruber, B Halliwell, R Gunawan Nucleic acids research 43 (8), 4098-4108, 2015 | 11 | 2015 |
Thermodynamic analysis of mitochondrial DNA breakpoints reveals mechanistic details of deletion mutagenesis LN Lakshmanan, Z Yee, J Gruber, B Halliwell, R Gunawan bioRxiv, 254631, 2018 | 3 | 2018 |
Thermodynamic analysis of DNA hybridization signatures near mitochondrial DNA deletion breakpoints LN Lakshmanan, Z Yee, B Halliwell, J Gruber, R Gunawan Iscience 24 (3), 2021 | | 2021 |
Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model. FS Fong Sheng, E Teo, NLF Ng LiFang, CCB Chen CeBelle, ... | | 2016 |
DIRECT REPEATS AND DELETIONS IN MITOCHONDRIAL DNA: CAUSAL AND EVOLUTIONARY ASPECTS LN LAKSHMANAN | | 2013 |
Role of Direct Repeats and DNA Misalignments in mtDNA Deletions: Cause or Coincidence? LN Lakshmanan, J Gruber, B Halliwell, R Gunawan Gordon Research Conference on Biology of Aging, 2012 | | 2012 |
Mitochondrial DNA Deletion Mutagenesis in Aging and mtDNA Misalignments LN Lakshmanan, J Gruber, R Gunawan The 13th International Conference on Systems Biology, 2012 | | 2012 |