Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure YC Ho, L Shan, NN Hosmane, J Wang, SB Laskey, DIS Rosenbloom, ... Cell 155 (3), 540-551, 2013 | 1545 | 2013 |
SARS-CoV-2: a storm is raging SF Pedersen, YC Ho The Journal of clinical investigation 130 (5), 2202-2205, 2020 | 1359 | 2020 |
Defective proviruses rapidly accumulate during acute HIV-1 infection KM Bruner, AJ Murray, RA Pollack, MG Soliman, SB Laskey, AA Capoferri, ... Nature medicine 22 (9), 1043-1049, 2016 | 754 | 2016 |
A quantitative approach for measuring the reservoir of latent HIV-1 proviruses KM Bruner, Z Wang, FR Simonetti, AM Bender, KJ Kwon, S Sengupta, ... Nature 566 (7742), 120-125, 2019 | 621 | 2019 |
Proliferation of latently infected CD4+ T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics NN Hosmane, KJ Kwon, KM Bruner, AA Capoferri, S Beg, ... Journal of Experimental Medicine 214 (4), 959-972, 2017 | 413 | 2017 |
Defective HIV-1 proviruses are expressed and can be recognized by cytotoxic T lymphocytes, which shape the proviral landscape RA Pollack, RB Jones, M Pertea, KM Bruner, AR Martin, AS Thomas, ... Cell host & microbe 21 (4), 494-506. e4, 2017 | 369 | 2017 |
Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient SA Yukl, E Boritz, M Busch, C Bentsen, TW Chun, D Douek, E Eisele, ... PLoS pathogens 9 (5), e1003347, 2013 | 361 | 2013 |
Expanded cellular clones carrying replication-competent HIV-1 persist, wax, and wane Z Wang, EE Gurule, TP Brennan, JM Gerold, KJ Kwon, NN Hosmane, ... Proceedings of the National Academy of Sciences 115 (11), E2575-E2584, 2018 | 257 | 2018 |
Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells SH Huang, Y Ren, AS Thomas, D Chan, S Mueller, AR Ward, S Patel, ... The Journal of clinical investigation 128 (2), 876-889, 2018 | 205 | 2018 |
Isolation and Characterization of a Vibrio vulnificus Mutant Deficient in Both Extracellular Metalloprotease and Cytolysin JJ Fan, CP Shao, YC Ho, CK Yu, LI Hor Infection and immunity 69 (9), 5943-5948, 2001 | 128 | 2001 |
Recommendations for measuring HIV reservoir size in cure-directed clinical trials M Abdel-Mohsen, D Richman, RF Siliciano, MC Nussenzweig, BJ Howell, ... Nature medicine 26 (9), 1339-1350, 2020 | 120 | 2020 |
Restriction of SARS-CoV-2 replication by targeting programmed− 1 ribosomal frameshifting Y Sun, L Abriola, RO Niederer, SF Pedersen, MM Alfajaro, ... Proceedings of the National Academy of Sciences 118 (26), e2023051118, 2021 | 116 | 2021 |
Single-cell transcriptional landscapes reveal HIV-1–driven aberrant host gene transcription as a potential therapeutic target R Liu, YHJ Yeh, A Varabyou, JA Collora, S Sherrill-Mix, CC Talbot Jr, ... Science translational medicine 12 (543), eaaz0802, 2020 | 98 | 2020 |
Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones JA Collora, R Liu, D Pinto-Santini, N Ravindra, C Ganoza, JR Lama, ... Immunity 55 (6), 1013-1031. e7, 2022 | 91 | 2022 |
The landscape of persistent viral genomes in ART-treated SIV, SHIV, and HIV-2 infections AM Bender, FR Simonetti, MR Kumar, EJ Fray, KM Bruner, AE Timmons, ... Cell host & microbe 26 (1), 73-85. e4, 2019 | 89 | 2019 |
Longitudinal study reveals HIV-1–infected CD4+ T cell dynamics during long-term antiretroviral therapy AAR Antar, KM Jenike, S Jang, DN Rigau, DB Reeves, R Hoh, MR Krone, ... The Journal of clinical investigation 130 (7), 3543-3559, 2020 | 83 | 2020 |
The forces driving clonal expansion of the HIV-1 latent reservoir R Liu, FR Simonetti, YC Ho Virology journal 17 (1), 4, 2020 | 83 | 2020 |
Prognostic factors for fatal adult influenza pneumonia YC Ho, JL Wang, JT Wang, UI Wu, CW Chang, HS Wu, CH Chen, ... Journal of Infection 58 (6), 439-445, 2009 | 74 | 2009 |
Sprouty-2 regulates HIV-specific T cell polyfunctionality YL Chiu, L Shan, H Huang, C Haupt, C Bessell, DH Canaday, H Zhang, ... The Journal of clinical investigation 124 (1), 198-208, 2014 | 61 | 2014 |
High levels of mecA DNA detected by a quantitative real-time PCR assay are associated with mortality in patients with methicillin-resistant Staphylococcus aureus bacteremia YC Ho, SC Chang, SR Lin, WK Wang Journal of clinical microbiology 47 (5), 1443-1451, 2009 | 57 | 2009 |