Cell-produced α-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival E Emmanouilidou, K Melachroinou, T Roumeliotis, SD Garbis, M Ntzouni, ... The Journal of Neuroscience 30 (20), 6838-6851, 2010 | 1293 | 2010 |
Proteogenomics of non-smoking lung cancer in East Asia delineates molecular signatures of pathogenesis and progression YJ Chen, TI Roumeliotis, YH Chang, CT Chen, CL Han, MH Lin, ... Cell 182 (1), 226-244. e17, 2020 | 259 | 2020 |
Single-cell transcriptomics identifies an effectorness gradient shaping the response of CD4+ T cells to cytokines E Cano-Gamez, B Soskic, TI Roumeliotis, E So, DJ Smyth, M Baldrighi, ... Nature communications 11 (1), 1801, 2020 | 241 | 2020 |
Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner JN Bianco, V Bergoglio, YL Lin, MJ Pillaire, AL Schmitz, J Gilhodes, ... Nature communications 10 (1), 910, 2019 | 139 | 2019 |
Biomarker discovery in low-grade breast cancer using isobaric stable isotope tags and two-dimensional liquid chromatography-tandem mass spectrometry (iTRAQ-2DLC-MS/MS) based … P Bouchal, T Roumeliotis, R Hrstka, R Nenutil, B Vojtesek, SD Garbis Journal of proteome research 8 (1), 362-373, 2009 | 137 | 2009 |
A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes EK Papachristou, K Kishore, AN Holding, K Harvey, TI Roumeliotis, ... Nature communications 9 (1), 2311, 2018 | 134 | 2018 |
Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer G Velimezi, M Liontos, K Vougas, T Roumeliotis, J Bartkova, M Sideridou, ... Nature cell biology 15 (8), 967-977, 2013 | 130 | 2013 |
Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells TI Roumeliotis, SP Williams, E Gonçalves, C Alsinet, ... Cell Reports 20 (9), 2201–2214, 2017 | 126 | 2017 |
A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage X Zou, GCC Koh, AS Nanda, A Degasperi, K Urgo, TI Roumeliotis, ... Nature cancer 2 (6), 643-657, 2021 | 125 | 2021 |
Search for potential markers for prostate cancer diagnosis, prognosis and treatment in clinical tissue specimens using amine-specific isobaric tagging (iTRAQ) with two … SD Garbis, SI Tyritzis, T Roumeliotis, P Zerefos, EG Giannopoulou, ... The Journal of Proteome Research 7 (8), 3146-3158, 2008 | 118 | 2008 |
Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis J Steinberg, GRS Ritchie, TI Roumeliotis, RL Jayasuriya, MJ Clark, ... Scientific reports 7 (1), 1-11, 2017 | 112 | 2017 |
PBRM1 deficiency confers synthetic lethality to DNA repair inhibitors in cancer RM Chabanon, D Morel, T Eychenne, L Colmet-Daage, I Bajrami, ... Cancer research 81 (11), 2888-2902, 2021 | 86 | 2021 |
Citrobacter rodentium subverts ATP flux and cholesterol homeostasis in intestinal epithelial cells in vivo CN Berger, VF Crepin, TI Roumeliotis, JC Wright, D Carson, ... Cell metabolism 26 (5), 738-752. e6, 2017 | 84 | 2017 |
Whole Serum 3D LC-nESI-FTMS Quantitative Proteomics Reveals Sexual Dimorphism in the Milieu Intérieur of Overweight and Obese Adults NM Al-Daghri, OS Al-Attas, HE Johnston, A Singhania, MS Alokail, ... Journal of proteome research 13 (11), 5094-5105, 2014 | 74 | 2014 |
A molecular quantitative trait locus map for osteoarthritis J Steinberg, L Southam, TI Roumeliotis, MJ Clark, RL Jayasuriya, D Swift, ... Nature Communications 12 (1), 1309, 2021 | 73 | 2021 |
Type III secretion system effectors form robust and flexible intracellular virulence networks D Ruano-Gallego, J Sanchez-Garrido, Z Kozik, E Nunez-Berrueco, ... Science 371 (6534), eabc9531, 2021 | 71 | 2021 |
Combined proteomics and transcriptomics identifies carboxypeptidase B1 and nuclear factor κB (NF-κB) associated proteins as putative biomarkers of metastasis in low grade … P Bouchal, M Dvořáková, T Roumeliotis, Z Bortlíček, I Ihnatová, ... Molecular & Cellular Proteomics 14 (7), 1814-1830, 2015 | 69 | 2015 |
A Novel multidimensional protein identification technology approach combining protein size exclusion prefractionation, peptide zwitterion− ion hydrophilic interaction … SD Garbis, TI Roumeliotis, SI Tyritzis, KM Zorpas, K Pavlakis, ... Analytical Chemistry 83 (3), 708-718, 2011 | 67 | 2011 |
CDK/CK1 inhibitors roscovitine and CR8 downregulate amplified MYCN in neuroblastoma cells C Delehouzé, K Godl, N Loaëc, C Bruyère, N Desban, N Oumata, ... Oncogene 33 (50), 5675-5687, 2014 | 66 | 2014 |
Exploiting induced pluripotent stem cell-derived macrophages to unravel host factors influencing Chlamydia trachomatis pathogenesis ATY Yeung, C Hale, AH Lee, EE Gill, W Bushell, D Parry-Smith, ... Nature communications 8 (1), 15013, 2017 | 65 | 2017 |