Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor RS Judson, FM Magpantay, V Chickarmane, C Haskell, N Tania, J Taylor, ... Toxicological Sciences 148 (1), 137-154, 2015 | 297 | 2015 |
Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ... Toxicological Sciences 152 (2), 323-339, 2016 | 273 | 2016 |
tcpl: the ToxCast pipeline for high-throughput screening data DL Filer, P Kothiya, RW Setzer, RS Judson, MT Martin Bioinformatics 33 (4), 618-620, 2017 | 224 | 2017 |
Test driving ToxCast: endocrine profiling for 1858 chemicals included in phase II D Filer, HB Patisaul, T Schug, D Reif, K Thayer Current opinion in pharmacology 19, 145-152, 2014 | 81 | 2014 |
Predictive Endocrine Testing in the 21st Century Using in Vitro Assays of Estrogen Receptor Signaling Responses DM Rotroff, MT Martin, DJ Dix, DL Filer, KA Houck, TB Knudsen, NS Sipes, ... Environmental science & technology 48 (15), 8706-8716, 2014 | 81 | 2014 |
Prioritizing environmental chemicals for obesity and diabetes outcomes research: a screening approach using ToxCast™ high-throughput data S Auerbach, D Filer, D Reif, V Walker, AC Holloway, J Schlezinger, ... Environmental health perspectives 124 (8), 1141-1154, 2016 | 76 | 2016 |
High-throughput screening of chemical effects on steroidogenesis using H295R human adrenocortical carcinoma cells AL Karmaus, CM Toole, DL Filer, KC Lewis, MT Martin Toxicological sciences 150 (2), 323-332, 2016 | 64 | 2016 |
Evaluation of food-relevant chemicals in the ToxCast high-throughput screening program AL Karmaus, DL Filer, MT Martin, KA Houck Food and Chemical Toxicology 92, 188-196, 2016 | 58 | 2016 |
Cross-species analysis of thyroperoxidase inhibition by xenobiotics demonstrates conservation of response between pig and rat KB Paul, JM Hedge, C Macherla, DL Filer, E Burgess, SO Simmons, ... Toxicology 312, 97-107, 2013 | 50 | 2013 |
Falciparum malaria from coastal Tanzania and Zanzibar remains highly connected despite effective control efforts on the archipelago AP Morgan, NF Brazeau, B Ngasala, LE Mhamilawa, M Denton, ... Malaria journal 19, 1-14, 2020 | 42 | 2020 |
The ToxCast analysis pipeline: An R package for processing and modeling chemical screening data DL Filer, P Kothiya, WR Setzer, RS Judson, MT Martin US Environmental Protection Agency: http://www. epa. gov/ncct/toxcast/files …, 2014 | 29 | 2014 |
Projected t-SNE for batch correction E Aliverti, JL Tilson, DL Filer, B Babcock, A Colaneri, J Ocasio, ... Bioinformatics 36 (11), 3522-3527, 2020 | 14 | 2020 |
On the utility of ToxCast-based predictive models to evaluate potential metabolic disruption by environmental chemicals DL Filer, K Hoffman, RM Sargis, L Trasande, CD Kassotis Environmental Health Perspectives 130 (5), 057005, 2022 | 12 | 2022 |
Curation of food-relevant chemicals in ToxCast AL Karmaus, TD Trautman, M Krishan, DL Filer, LA Fix Food and Chemical Toxicology 103, 174-182, 2017 | 12 | 2017 |
The new ToxCast analysis DL Filer Available through filer. dayne@ epa. gov, 2019 | 5 | 2019 |
Association of predicted expression and multimodel association analysis of substance abuse traits DM Bost, C Bizon, JL Tilson, DL Filer, IR Gizer, KC Wilhelmsen Complex Psychiatry 8 (1-2), 35-46, 2022 | 4 | 2022 |
Noninvasive prenatal exome sequencing diagnostic utility limited by sequencing depth and fetal fraction DL Filer, PA Mieczkowski, A Brandt, KL Gilmore, BC Powell, JS Berg, ... Prenatal diagnosis 42 (5), 567-573, 2022 | 3 | 2022 |
Pre-capture multiplexing provides additional power to detect copy number variation in exome sequencing DL Filer, F Kuo, AT Brandt, CR Tilley, PA Mieczkowski, JS Berg, ... BMC bioinformatics 22, 1-16, 2021 | 3 | 2021 |
Using ToxCast/Tox21 Assays and QSAR Modeling to Predict Androgen Receptor Pathway Activity N Kleinstreuer, Q Zang, D Filer, M Martin, K Houck, D Allen, W Casey, ... SOT March, 22-26, 2015 | 1 | 2015 |
A greedy regression algorithm with coarse weights offers novel advantages CD Jeffries, JR Ford, JL Tilson, DO Perkins, DM Bost, DL Filer, ... Scientific Reports 12 (1), 5440, 2022 | | 2022 |