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Dayne Lewis Filer, MD, PhD
Dayne Lewis Filer, MD, PhD
Resident Physician, Obstetrics & Gynecology, Duke University Hospital
Verified email at duke.edu - Homepage
Title
Cited by
Cited by
Year
Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor
RS Judson, FM Magpantay, V Chickarmane, C Haskell, N Tania, J Taylor, ...
Toxicological Sciences 148 (1), 137-154, 2015
2972015
Editor's Highlight: Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space
R Judson, K Houck, M Martin, AM Richard, TB Knudsen, I Shah, S Little, ...
Toxicological Sciences 152 (2), 323-339, 2016
2732016
tcpl: the ToxCast pipeline for high-throughput screening data
DL Filer, P Kothiya, RW Setzer, RS Judson, MT Martin
Bioinformatics 33 (4), 618-620, 2017
2242017
Test driving ToxCast: endocrine profiling for 1858 chemicals included in phase II
D Filer, HB Patisaul, T Schug, D Reif, K Thayer
Current opinion in pharmacology 19, 145-152, 2014
812014
Predictive Endocrine Testing in the 21st Century Using in Vitro Assays of Estrogen Receptor Signaling Responses
DM Rotroff, MT Martin, DJ Dix, DL Filer, KA Houck, TB Knudsen, NS Sipes, ...
Environmental science & technology 48 (15), 8706-8716, 2014
812014
Prioritizing environmental chemicals for obesity and diabetes outcomes research: a screening approach using ToxCast™ high-throughput data
S Auerbach, D Filer, D Reif, V Walker, AC Holloway, J Schlezinger, ...
Environmental health perspectives 124 (8), 1141-1154, 2016
762016
High-throughput screening of chemical effects on steroidogenesis using H295R human adrenocortical carcinoma cells
AL Karmaus, CM Toole, DL Filer, KC Lewis, MT Martin
Toxicological sciences 150 (2), 323-332, 2016
642016
Evaluation of food-relevant chemicals in the ToxCast high-throughput screening program
AL Karmaus, DL Filer, MT Martin, KA Houck
Food and Chemical Toxicology 92, 188-196, 2016
582016
Cross-species analysis of thyroperoxidase inhibition by xenobiotics demonstrates conservation of response between pig and rat
KB Paul, JM Hedge, C Macherla, DL Filer, E Burgess, SO Simmons, ...
Toxicology 312, 97-107, 2013
502013
Falciparum malaria from coastal Tanzania and Zanzibar remains highly connected despite effective control efforts on the archipelago
AP Morgan, NF Brazeau, B Ngasala, LE Mhamilawa, M Denton, ...
Malaria journal 19, 1-14, 2020
422020
The ToxCast analysis pipeline: An R package for processing and modeling chemical screening data
DL Filer, P Kothiya, WR Setzer, RS Judson, MT Martin
US Environmental Protection Agency: http://www. epa. gov/ncct/toxcast/files …, 2014
292014
Projected t-SNE for batch correction
E Aliverti, JL Tilson, DL Filer, B Babcock, A Colaneri, J Ocasio, ...
Bioinformatics 36 (11), 3522-3527, 2020
142020
On the utility of ToxCast-based predictive models to evaluate potential metabolic disruption by environmental chemicals
DL Filer, K Hoffman, RM Sargis, L Trasande, CD Kassotis
Environmental Health Perspectives 130 (5), 057005, 2022
122022
Curation of food-relevant chemicals in ToxCast
AL Karmaus, TD Trautman, M Krishan, DL Filer, LA Fix
Food and Chemical Toxicology 103, 174-182, 2017
122017
The new ToxCast analysis
DL Filer
Available through filer. dayne@ epa. gov, 2019
52019
Association of predicted expression and multimodel association analysis of substance abuse traits
DM Bost, C Bizon, JL Tilson, DL Filer, IR Gizer, KC Wilhelmsen
Complex Psychiatry 8 (1-2), 35-46, 2022
42022
Noninvasive prenatal exome sequencing diagnostic utility limited by sequencing depth and fetal fraction
DL Filer, PA Mieczkowski, A Brandt, KL Gilmore, BC Powell, JS Berg, ...
Prenatal diagnosis 42 (5), 567-573, 2022
32022
Pre-capture multiplexing provides additional power to detect copy number variation in exome sequencing
DL Filer, F Kuo, AT Brandt, CR Tilley, PA Mieczkowski, JS Berg, ...
BMC bioinformatics 22, 1-16, 2021
32021
Using ToxCast/Tox21 Assays and QSAR Modeling to Predict Androgen Receptor Pathway Activity
N Kleinstreuer, Q Zang, D Filer, M Martin, K Houck, D Allen, W Casey, ...
SOT March, 22-26, 2015
12015
A greedy regression algorithm with coarse weights offers novel advantages
CD Jeffries, JR Ford, JL Tilson, DO Perkins, DM Bost, DL Filer, ...
Scientific Reports 12 (1), 5440, 2022
2022
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Articles 1–20