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Pitcher JA
Pitcher JA
Unknown affiliation
Verified email at ucl.ac.uk
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G protein–coupled receptor kinases
JA Pitcher, NJ Freedman, RJ Lefkowitz
Annual review of biochemistry 67 (1), 653-692, 1998
16631998
Role of βγ subunits of G proteins in targeting the β-adrenergic receptor kinase to membrane-bound receptors
JA Pitcher, J Inglese, JB Higgins, JL Arriza, PJ Casey, C Kim, JL Benovic, ...
Science 257 (5074), 1264-1267, 1992
9441992
The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange
RA Hall, RT Premont, CW Chow, JT Blitzer, JA Pitcher, A Claing, ...
Nature 392 (6676), 626-630, 1998
7481998
Binding of G protein beta gamma-subunits to pleckstrin homology domains.
K Touhara, J Inglese, JA Pitcher, G Shaw, RJ Lefkowitz
Journal of Biological Chemistry 269 (14), 10217-10220, 1994
6351994
The role of sequestration in G protein-coupled receptor resensitization: regulation of β2-adrenergic receptor dephosphorylation by vesicular acidification
KM Krueger, Y Daaka, JA Pitcher, RJ Lefkowitz
Journal of Biological Chemistry 272 (1), 5-8, 1997
4891997
Keeping G proteins at bay: A complex between G protein-coupled receptor kinase 2 and Gßγ
DT Lodowski, JA Pitcher, WD Capel, RJ Lefkowitz, JJG Tesmer
Science 300 (5623), 1256-1262, 2003
4782003
Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and …
MJ Lohse, S Andexinger, J Pitcher, S Trukawinski, J Codina, JP Faure, ...
Journal of Biological Chemistry 267 (12), 8558-8564, 1992
4711992
Pleckstrin homology domain-mediated membrane association and activation of the β-adrenergic receptor kinase requires coordinate interaction with Gβγ subunits and lipid
JA Pitcher, K Touhara, ES Payne, RJ Lefkowitz
Journal of Biological Chemistry 270 (20), 11707-11710, 1995
4561995
β2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein
RT Premont, A Claing, N Vitale, JLR Freeman, JA Pitcher, WA Patton, ...
Proceedings of the National Academy of Sciences 95 (24), 14082-14087, 1998
3811998
Clathrin-mediated endocytosis of the β-adrenergic receptor is regulated by phosphorylation/dephosphorylation of β-arrestin1
FT Lin, KM Krueger, HE Kendall, Y Daaka, ZL Fredericks, JA Pitcher, ...
Journal of Biological Chemistry 272 (49), 31051-31057, 1997
3271997
Identification of the G protein-coupled receptor kinase phosphorylation sites in the human β2-adrenergic receptor
ZL Fredericks, JA Pitcher, RJ Lefkowitz
Journal of Biological Chemistry 271 (23), 13796-13803, 1996
2921996
Characterization of the G Protein-coupled Receptor Kinase GRK4: IDENTIFICATION OF FOUR SPLICE VARIANTS (∗)
RT Premont, AD Macrae, RH Stoffel, N Chung, JA Pitcher, C Ambrose, ...
Journal of Biological Chemistry 271 (11), 6403-6410, 1996
2641996
Desensitization of the isolated. beta. 2-adrenergic receptor by. beta.-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct …
J Pitcher, MJ Lohse, J Codina, MG Caron, RJ Lefkowitz
Biochemistry 31 (12), 3193-3197, 1992
2631992
Receptor and Gβγ isoform-specific interactions with G protein-coupled receptor kinases
Y Daaka, JA Pitcher, M Richardson, RH Stoffel, JD Robishaw, ...
Proceedings of the National Academy of Sciences 94 (6), 2180-2185, 1997
2621997
Mechanisms of β-adrenergic receptor desensitization and resensitization
RJ Lefkowitz, J Pitcher, K Krueger, Y Daaka
Advances in pharmacology 42, 416-420, 1997
2621997
Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes
JS Martini, P Raake, LE Vinge, BR DeGeorge Jr, JK Chuprun, DM Harris, ...
Proceedings of the National Academy of Sciences 105 (34), 12457-12462, 2008
2602008
The G-protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity.
JA Pitcher, ES Payne, C Csortos, AA DePaoli-Roach, RJ Lefkowitz
Proceedings of the National Academy of Sciences 92 (18), 8343-8347, 1995
2521995
Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases
JA Pitcher, JJG Tesmer, JLR Freeman, WD Capel, WC Stone, ...
Journal of Biological Chemistry 274 (49), 34531-34534, 1999
2431999
Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79
M Cong, SJ Perry, FT Lin, ID Fraser, LA Hu, W Chen, JA Pitcher, JD Scott, ...
Journal of Biological Chemistry 276 (18), 15192-15199, 2001
2322001
Phosphatidylinositol 4, 5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity: Location, structure, and regulation of the PIP2 binding site …
JA Pitcher, ZL Fredericks, WC Stone, RT Premont, RH Stoffel, WJ Koch, ...
Journal of Biological Chemistry 271 (40), 24907-24913, 1996
2251996
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