G protein–coupled receptor kinases JA Pitcher, NJ Freedman, RJ Lefkowitz Annual review of biochemistry 67 (1), 653-692, 1998 | 1663 | 1998 |
Role of βγ subunits of G proteins in targeting the β-adrenergic receptor kinase to membrane-bound receptors JA Pitcher, J Inglese, JB Higgins, JL Arriza, PJ Casey, C Kim, JL Benovic, ... Science 257 (5074), 1264-1267, 1992 | 944 | 1992 |
The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange RA Hall, RT Premont, CW Chow, JT Blitzer, JA Pitcher, A Claing, ... Nature 392 (6676), 626-630, 1998 | 748 | 1998 |
Binding of G protein beta gamma-subunits to pleckstrin homology domains. K Touhara, J Inglese, JA Pitcher, G Shaw, RJ Lefkowitz Journal of Biological Chemistry 269 (14), 10217-10220, 1994 | 635 | 1994 |
The role of sequestration in G protein-coupled receptor resensitization: regulation of β2-adrenergic receptor dephosphorylation by vesicular acidification KM Krueger, Y Daaka, JA Pitcher, RJ Lefkowitz Journal of Biological Chemistry 272 (1), 5-8, 1997 | 489 | 1997 |
Keeping G proteins at bay: A complex between G protein-coupled receptor kinase 2 and Gßγ DT Lodowski, JA Pitcher, WD Capel, RJ Lefkowitz, JJG Tesmer Science 300 (5623), 1256-1262, 2003 | 478 | 2003 |
Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and … MJ Lohse, S Andexinger, J Pitcher, S Trukawinski, J Codina, JP Faure, ... Journal of Biological Chemistry 267 (12), 8558-8564, 1992 | 471 | 1992 |
Pleckstrin homology domain-mediated membrane association and activation of the β-adrenergic receptor kinase requires coordinate interaction with Gβγ subunits and lipid JA Pitcher, K Touhara, ES Payne, RJ Lefkowitz Journal of Biological Chemistry 270 (20), 11707-11710, 1995 | 456 | 1995 |
β2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein RT Premont, A Claing, N Vitale, JLR Freeman, JA Pitcher, WA Patton, ... Proceedings of the National Academy of Sciences 95 (24), 14082-14087, 1998 | 381 | 1998 |
Clathrin-mediated endocytosis of the β-adrenergic receptor is regulated by phosphorylation/dephosphorylation of β-arrestin1 FT Lin, KM Krueger, HE Kendall, Y Daaka, ZL Fredericks, JA Pitcher, ... Journal of Biological Chemistry 272 (49), 31051-31057, 1997 | 327 | 1997 |
Identification of the G protein-coupled receptor kinase phosphorylation sites in the human β2-adrenergic receptor ZL Fredericks, JA Pitcher, RJ Lefkowitz Journal of Biological Chemistry 271 (23), 13796-13803, 1996 | 292 | 1996 |
Characterization of the G Protein-coupled Receptor Kinase GRK4: IDENTIFICATION OF FOUR SPLICE VARIANTS (∗) RT Premont, AD Macrae, RH Stoffel, N Chung, JA Pitcher, C Ambrose, ... Journal of Biological Chemistry 271 (11), 6403-6410, 1996 | 264 | 1996 |
Desensitization of the isolated. beta. 2-adrenergic receptor by. beta.-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct … J Pitcher, MJ Lohse, J Codina, MG Caron, RJ Lefkowitz Biochemistry 31 (12), 3193-3197, 1992 | 263 | 1992 |
Receptor and Gβγ isoform-specific interactions with G protein-coupled receptor kinases Y Daaka, JA Pitcher, M Richardson, RH Stoffel, JD Robishaw, ... Proceedings of the National Academy of Sciences 94 (6), 2180-2185, 1997 | 262 | 1997 |
Mechanisms of β-adrenergic receptor desensitization and resensitization RJ Lefkowitz, J Pitcher, K Krueger, Y Daaka Advances in pharmacology 42, 416-420, 1997 | 262 | 1997 |
Uncovering G protein-coupled receptor kinase-5 as a histone deacetylase kinase in the nucleus of cardiomyocytes JS Martini, P Raake, LE Vinge, BR DeGeorge Jr, JK Chuprun, DM Harris, ... Proceedings of the National Academy of Sciences 105 (34), 12457-12462, 2008 | 260 | 2008 |
The G-protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity. JA Pitcher, ES Payne, C Csortos, AA DePaoli-Roach, RJ Lefkowitz Proceedings of the National Academy of Sciences 92 (18), 8343-8347, 1995 | 252 | 1995 |
Feedback inhibition of G protein-coupled receptor kinase 2 (GRK2) activity by extracellular signal-regulated kinases JA Pitcher, JJG Tesmer, JLR Freeman, WD Capel, WC Stone, ... Journal of Biological Chemistry 274 (49), 34531-34534, 1999 | 243 | 1999 |
Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79 M Cong, SJ Perry, FT Lin, ID Fraser, LA Hu, W Chen, JA Pitcher, JD Scott, ... Journal of Biological Chemistry 276 (18), 15192-15199, 2001 | 232 | 2001 |
Phosphatidylinositol 4, 5-bisphosphate (PIP2)-enhanced G protein-coupled receptor kinase (GRK) activity: Location, structure, and regulation of the PIP2 binding site … JA Pitcher, ZL Fredericks, WC Stone, RT Premont, RH Stoffel, WJ Koch, ... Journal of Biological Chemistry 271 (40), 24907-24913, 1996 | 225 | 1996 |