The PD‐1 pathway in tolerance and autoimmunity LM Francisco, PT Sage, AH Sharpe Immunological reviews 236 (1), 219-242, 2010 | 2739 | 2010 |
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells LM Francisco, VH Salinas, KE Brown, VK Vanguri, GJ Freeman, ... Journal of Experimental Medicine 206 (13), 3015-3029, 2009 | 2424 | 2009 |
Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells B Sauter, ML Albert, L Francisco, M Larsson, S Somersan, N Bhardwaj The Journal of experimental medicine 191 (3), 423-434, 2000 | 1766 | 2000 |
Immature Dendritic Cells Phagocytose Apoptotic Cells via αvβ5 and CD36, and Cross-present Antigens to Cytotoxic T Lymphocytes ML Albert, SFA Pearce, LM Francisco, B Sauter, P Roy, RL Silverstein, ... The Journal of experimental medicine 188 (7), 1359-1368, 1998 | 1728 | 1998 |
Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF M Quigley, F Pereyra, B Nilsson, F Porichis, C Fonseca, Q Eichbaum, ... Nature medicine 16 (10), 1147-1151, 2010 | 613 | 2010 |
Blockade of CTLA-4 on CD4+ CD25+ regulatory T cells abrogates their function in vivo S Read, R Greenwald, A Izcue, N Robinson, D Mandelbrot, L Francisco, ... The Journal of Immunology 177 (7), 4376-4383, 2006 | 560 | 2006 |
PD-1 and its ligands in T-cell immunity ME Keir, LM Francisco, AH Sharpe Current opinion in immunology 19 (3), 309-314, 2007 | 552 | 2007 |
Tumor-specific killer cells in paraneoplastic cerebellar degeneration ML Albert, JC Darnell, A Bender, LM Francisco, N Bhardwaj, RB Darnell Nature medicine 4 (11), 1321-1324, 1998 | 536 | 1998 |
The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood PT Sage, LM Francisco, CV Carman, AH Sharpe Nature immunology 14 (2), 152-161, 2013 | 522 | 2013 |
RGMb is a novel binding partner for PD-L2 and its engagement with PD-L2 promotes respiratory tolerance Y Xiao, S Yu, B Zhu, D Bedoret, X Bu, LM Francisco, P Hua, ... Journal of Experimental Medicine 211 (5), 943-959, 2014 | 352 | 2014 |
Interleukin-27 priming of T cells controls IL-17 production in trans via induction of the ligand PD-L1 K Hirahara, K Ghoreschi, XP Yang, H Takahashi, A Laurence, G Vahedi, ... Immunity 36 (6), 1017-1030, 2012 | 305 | 2012 |
PD-1 restraint of regulatory T cell suppressive activity is critical for immune tolerance CL Tan, JR Kuchroo, PT Sage, D Liang, LM Francisco, J Buck, YR Thaker, ... Journal of Experimental Medicine 218 (1), 2021 | 221 | 2021 |
The PTEN pathway in Tregs is a critical driver of the suppressive tumor microenvironment MD Sharma, R Shinde, TL McGaha, L Huang, RB Holmgaard, ... Science advances 1 (10), e1500845, 2015 | 185 | 2015 |
Intestinal tolerance is converted to autoimmune enteritis upon PD-1 ligand blockade ED Reynoso, KG Elpek, L Francisco, R Bronson, A Bellemare-Pelletier, ... The Journal of Immunology 182 (4), 2102-2112, 2009 | 147 | 2009 |
The PD-1 pathway regulates development and function of memory CD8+ T cells following respiratory viral infection KE Pauken, J Godec, PM Odorizzi, KE Brown, KB Yates, SF Ngiow, ... Cell reports 31 (13), 2020 | 99 | 2020 |
Physiologic control of IDO competence in splenic dendritic cells B Baban, PR Chandler, BA Johnson, L Huang, M Li, ML Sharpe, ... The Journal of Immunology 187 (5), 2329-2335, 2011 | 95 | 2011 |
B7‐1/2, but not PD‐L1/2 molecules, are required on IL‐10‐treated tolerogenic DC and DC‐derived exosomes for in vivo function MA Ruffner, SH Kim, NR Bianco, LM Francisco, AH Sharpe, PD Robbins European journal of immunology 39 (11), 3084-3090, 2009 | 82 | 2009 |
Role of the immune modulator programmed cell death-1 during development and apoptosis of mouse retinal ganglion cells L Chen, CW Sham, AM Chan, LM Francisco, Y Wu, S Mareninov, ... Investigative ophthalmology & visual science 50 (10), 4941-4948, 2009 | 26 | 2009 |
A set of genes selectively expressed in murine dendritic cells: utility of related cis-acting sequences for lentiviral gene transfer KS Gorski, T Shin, E Crafton, M Otsuji, FM Rattis, X Huang, E Kelleher, ... Molecular immunology 40 (1), 35-47, 2003 | 17 | 2003 |
Neuronal programmed cell death-1 ligand expression regulates retinal ganglion cell number in neonatal and adult mice CW Sham, AM Chan, JMK Kwong, J Caprioli, S Nusinowitz, B Chen, ... Journal of Neuro-Ophthalmology 32 (3), 227-237, 2012 | 16 | 2012 |