Articles with public access mandates - Luca LaraiaLearn more
Not available anywhere: 5
Small molecule probes for targeting autophagy
T Whitmarsh-Everiss, L Laraia
Nature chemical biology 17 (6), 653-664, 2021
Mandates: Danish Council for Independent Research, Carlsberg Foundation DK
Natural product inspired compound collections: evolutionary principle, chemical synthesis, phenotypic screening, and target identification
L Laraia, H Waldmann
Drug Discovery Today: Technologies 23, 75-82, 2017
Mandates: European Commission
Synthesis and biological profiling of tellimagrandin I and analogues reveals that the medium ring can significantly modulate biological activity
S Zheng, L Laraia, CJ O'Connor, D Sorrell, YS Tan, Z Xu, ...
Organic & Biomolecular Chemistry 10 (13), 2590-2593, 2012
Mandates: Cancer Research UK
Redshifted and thermally bistable one-way quantitative hemithioindigo-derived photoswitches enabled by isomer-specific excited state intramolecular proton transfer
M Krell-Jørgensen, H Zulfikri, MG Bonnevie, FS Bro, AO Dohn, L Laraia
Chemical Communications 59 (5), 563-566, 2023
Mandates: Danish Council for Independent Research, Icelandic Centre for Research
Identification of 5-HT2 serotonin receptor modulators through the synthesis of a diverse, tropane-and quinuclidine-alkaloid-inspired compound library
R Yao, AA Jensen, HP Bryce-Rogers, K Schultz-Knudsen, L Zhou, ...
Journal of Medicinal Chemistry 66 (16), 11536-11554, 2023
Mandates: Danish Council for Independent Research, Carlsberg Foundation DK
Available somewhere: 36
Functionalised staple linkages for modulating the cellular activity of stapled peptides
YH Lau, P De Andrade, ST Quah, M Rossmann, L Laraia, N Sköld, ...
Chemical science 5 (5), 1804-1809, 2014
Mandates: A*Star, Singapore, UK Biotechnology and Biological Sciences Research Council …
Overcoming chemical, biological, and computational challenges in the development of inhibitors targeting protein-protein interactions
L Laraia, G McKenzie, DR Spring, AR Venkitaraman, DJ Huggins
Chemistry & biology 22 (6), 689-703, 2015
Mandates: UK Biotechnology and Biological Sciences Research Council, UK Engineering …
Chemical genetics
CJ O'Connor, L Laraia, DR Spring
Chemical Society Reviews 40 (8), 4332-4345, 2011
Mandates: Cancer Research UK
Diversity-oriented synthesis as a tool for identifying new modulators of mitosis
BM Ibbeson*, L Laraia*, E Alza, CJ O'Connor, YS Tan, HML Davies, ...
Nature Communications 5, 2014
Mandates: A*Star, Singapore, UK Biotechnology and Biological Sciences Research Council …
Stereoselective Synthesis of cis- and trans-2,3-Disubstituted Tetrahydrofurans via Oxonium−Prins Cyclization: Access to the Cordigol Ring System
AC Spivey, L Laraia, AR Bayly, HS Rzepa, AJP White
Organic letters 12 (5), 900-903, 2010
Mandates: Cancer Research UK
Discovery of novel cinchona‐alkaloid‐inspired oxazatwistane autophagy inhibitors
L Laraia, K Ohsawa, G Konstantinidis, L Robke, YW Wu, K Kumar, ...
Angewandte Chemie International Edition 56 (8), 2145-2150, 2017
Mandates: European Commission
Synthesis of Indomorphan pseudo‐natural product inhibitors of glucose transporters GLUT‐1 and‐3
J Ceballos, M Schwalfenberg, G Karageorgis, ES Reckzeh, S Sievers, ...
Angewandte Chemie 131 (47), 17172-17181, 2019
Mandates: Swiss National Science Foundation, Swedish Research Council, European Commission
The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis
L Laraia, A Friese, DP Corkery, G Konstantinidis, N Erwin, W Hofer, ...
Nature chemical biology 15 (7), 710-720, 2019
Mandates: US National Institutes of Health, Canadian Institutes of Health Research …
Phenotypic Identification of a Novel Autophagy Inhibitor Chemotype Targeting Lipid Kinase VPS34
L Robke, L Laraia, MA Carnero Corrales, G Konstantinidis, M Muroi, ...
Angewandte Chemie International Edition, 2017
Mandates: Swiss National Science Foundation, European Commission
Image‐based morphological profiling identifies a lysosomotropic, Iron‐sequestering autophagy inhibitor
L Laraia, G Garivet, DJ Foley, N Kaiser, S Müller, S Zinken, T Pinkert, ...
Angewandte Chemie International Edition 59 (14), 5721-5729, 2020
Mandates: Canadian Institutes of Health Research, German Research Foundation, Knut and …
Phenotyping reveals targets of a pseudo‐Natural‐product autophagy inhibitor
DJ Foley, S Zinken, D Corkery, L Laraia, A Pahl, YW Wu, H Waldmann
Angewandte Chemie International Edition 59 (30), 12470-12476, 2020
Mandates: Canadian Institutes of Health Research, Knut and Alice Wallenberg Foundation …
Small-molecule inhibitors of reactive oxygen species production
E Sassetti, MH Clausen, L Laraia
Journal of Medicinal Chemistry 64 (9), 5252-5275, 2021
Mandates: Danish Council for Independent Research, Carlsberg Foundation DK
Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin
MAC Corrales, S Zinken, G Konstantinidis, M Rafehi, A Abdelrahman, ...
Cell chemical biology 28 (12), 1750-1757. e5, 2021
Mandates: Swiss National Science Foundation, German Research Foundation, Knut and …
Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I
L Robke, Y Futamura, G Konstantinidis, J Wilke, H Aono, Z Mahmoud, ...
Chemical science 9 (11), 3014-3022, 2018
Mandates: European Commission
A two-directional strategy for the diversity-oriented synthesis of macrocyclic scaffolds
KMG O'Connell, HSG Beckmann, L Laraia, HT Horsley, A Bender, ...
Organic & Biomolecular Chemistry 10 (37), 7545-7551, 2012
Mandates: Cancer Research UK
Publication and funding information is determined automatically by a computer program