| Functionalised staple linkages for modulating the cellular activity of stapled peptides YH Lau, P De Andrade, ST Quah, M Rossmann, L Laraia, N Sköld, ... Chemical science 5 (5), 1804-1809, 2014 | 215 | 2014 |
| Principle and design of pseudo-natural products G Karageorgis, DJ Foley, L Laraia, H Waldmann Nature Chemistry 12 (3), 227-235, 2020 | 180 | 2020 |
| Overcoming chemical, biological, and computational challenges in the development of inhibitors targeting protein-protein interactions L Laraia, G McKenzie, DR Spring, AR Venkitaraman, DJ Huggins Chemistry & biology 22 (6), 689-703, 2015 | 163 | 2015 |
| Chemical genetics CJ O'Connor, L Laraia, DR Spring Chemical Society Reviews 40 (8), 4332-4345, 2011 | 163 | 2011 |
| Pseudo natural products—chemical evolution of natural product structure G Karageorgis, DJ Foley, L Laraia, S Brakmann, H Waldmann Angewandte Chemie International Edition 60 (29), 15705-15723, 2021 | 99 | 2021 |
| Diversity-oriented synthesis as a tool for identifying new modulators of mitosis BM Ibbeson*, L Laraia*, E Alza, CJ O'Connor, YS Tan, HML Davies, ... Nature Communications 5, 2014 | 92 | 2014 |
| Stereoselective Synthesis of cis- and trans-2,3-Disubstituted Tetrahydrofurans via Oxonium−Prins Cyclization: Access to the Cordigol Ring System AC Spivey, L Laraia, AR Bayly, HS Rzepa, AJP White Organic letters 12 (5), 900-903, 2010 | 90 | 2010 |
| Small molecule probes for targeting autophagy T Whitmarsh-Everiss, L Laraia Nature chemical biology 17 (6), 653-664, 2021 | 78 | 2021 |
| Discovery of novel cinchona‐alkaloid‐inspired oxazatwistane autophagy inhibitors L Laraia, K Ohsawa, G Konstantinidis, L Robke, YW Wu, K Kumar, ... Angewandte Chemie International Edition 56 (8), 2145-2150, 2017 | 78 | 2017 |
| Synthesis of Indomorphan pseudo‐natural product inhibitors of glucose transporters GLUT‐1 and‐3 J Ceballos, M Schwalfenberg, G Karageorgis, ES Reckzeh, S Sievers, ... Angewandte Chemie 131 (47), 17172-17181, 2019 | 76 | 2019 |
| The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis L Laraia, A Friese, DP Corkery, G Konstantinidis, N Erwin, W Hofer, ... Nature chemical biology 15 (7), 710-720, 2019 | 73 | 2019 |
| New Prodigiosin Derivatives Obtained by Mutasynthesis in Pseudomonas putida AS Klein, A Domröse, P Bongen, HUC Brass, T Classen, A Loeschcke, ... ACS synthetic biology 6 (9), 1757-1765, 2017 | 73 | 2017 |
| Natural product inspired compound collections: evolutionary principle, chemical synthesis, phenotypic screening, and target identification L Laraia, H Waldmann Drug Discovery Today: Technologies 23, 75-82, 2017 | 71 | 2017 |
| Highly Enantioselective Catalytic Vinylogous Propargylation of Coumarins Yields a Novel Autophagy Inhibitor Class H Xu, L Laraia, L Schneider, K Louven, C Strohmann, AP Antonchick, ... Angewandte Chemie International Edition, 2017 | 71 | 2017 |
| Phenotypic Identification of a Novel Autophagy Inhibitor Chemotype Targeting Lipid Kinase VPS34 L Robke, L Laraia, MA Carnero Corrales, G Konstantinidis, M Muroi, ... Angewandte Chemie International Edition, 2017 | 69 | 2017 |
| Bioactive compound collections: from design to target identification L Laraia, L Robke, H Waldmann Chem 4 (4), 705-730, 2018 | 58 | 2018 |
| Image‐based morphological profiling identifies a lysosomotropic, Iron‐sequestering autophagy inhibitor L Laraia, G Garivet, DJ Foley, N Kaiser, S Müller, S Zinken, T Pinkert, ... Angewandte Chemie International Edition 59 (14), 5721-5729, 2020 | 57 | 2020 |
| Phenotyping reveals targets of a pseudo‐Natural‐product autophagy inhibitor DJ Foley, S Zinken, D Corkery, L Laraia, A Pahl, YW Wu, H Waldmann Angewandte Chemie International Edition 59 (30), 12470-12476, 2020 | 53 | 2020 |
| Synthesis and biological profiling of tellimagrandin I and analogues reveals that the medium ring can significantly modulate biological activity S Zheng, L Laraia, CJ O'Connor, D Sorrell, YS Tan, Z Xu, ... Organic & Biomolecular Chemistry 10 (13), 2590-2593, 2012 | 53 | 2012 |
| Small-molecule inhibitors of reactive oxygen species production E Sassetti, MH Clausen, L Laraia Journal of Medicinal Chemistry 64 (9), 5252-5275, 2021 | 49 | 2021 |
Herbert WaldmannMax-Planck-Institut DortmundVerified email at mpi-dortmund.mpg.de
