| Integrative analysis of 111 reference human epigenomes A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, A Heravi-Moussavi, ... Nature 518 (7539), 317-330, 2015 | 6312 | 2015 |
| Gene silencing in mammals by small interfering RNAs MT McManus, PA Sharp Nature reviews genetics 3 (10), 737-747, 2002 | 2351 | 2002 |
| A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference DA Rubinson, CP Dillon, AV Kwiatkowski, C Sievers, L Yang, J Kopinja, ... Nature genetics 33 (3), 401-406, 2003 | 2113 | 2003 |
| Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2 Y Zhao, JF Ransom, A Li, V Vedantham, M von Drehle, AN Muth, ... Cell 129 (2), 303-317, 2007 | 1880 | 2007 |
| Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition MJ Hangauer, VS Viswanathan, MJ Ryan, D Bole, JK Eaton, A Matov, ... Nature 551 (7679), 247-250, 2017 | 1352 | 2017 |
| TAZ, a transcriptional modulator of mesenchymal stem cell differentiation JH Hong, ES Hwang, MT McManus, A Amsterdam, Y Tian, R Kalmukova, ... Science 309 (5737), 1074-1078, 2005 | 1181 | 2005 |
| Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs MJ Hangauer, IW Vaughn, MT McManus PLoS genetics 9 (6), e1003569, 2013 | 862 | 2013 |
| The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb BD Harfe, MT McManus, JH Mansfield, E Hornstein, CJ Tabin Proceedings of the National Academy of Sciences 102 (31), 10898-10903, 2005 | 809 | 2005 |
| RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription Q Ge, MT McManus, T Nguyen, CH Shen, PA Sharp, HN Eisen, J Chen Proceedings of the National Academy of Sciences 100 (5), 2718-2723, 2003 | 757 | 2003 |
| Cre-lox-regulated conditional RNA interference from transgenes A Ventura, A Meissner, CP Dillon, M McManus, PA Sharp, L Van Parijs, ... Proceedings of the National Academy of Sciences 101 (28), 10380-10385, 2004 | 749 | 2004 |
| IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2 JP Upton, L Wang, D Han, ES Wang, NE Huskey, L Lim, M Truitt, ... Science 338 (6108), 818-822, 2012 | 739 | 2012 |
| Selective miRNA disruption in T reg cells leads to uncontrolled autoimmunity X Zhou, LT Jeker, BT Fife, S Zhu, MS Anderson, MT McManus, ... The Journal of experimental medicine 205 (9), 1983-1991, 2008 | 674 | 2008 |
| Choosing the right tool for the job: RNAi, TALEN, or CRISPR M Boettcher, MT McManus Molecular cell 58 (4), 575-585, 2015 | 653 | 2015 |
| Dicer1 and miR-219 Are required for normal oligodendrocyte differentiation and myelination JC Dugas, TL Cuellar, A Scholze, B Ason, A Ibrahim, B Emery, ... Neuron 65 (5), 597-611, 2010 | 644 | 2010 |
| Chd1 regulates open chromatin and pluripotency of embryonic stem cells A Gaspar-Maia, A Alajem, F Polesso, R Sridharan, MJ Mason, ... nature 460 (7257), 863-868, 2009 | 608 | 2009 |
| Gene silencing using micro-RNA designed hairpins MT McManus, CP Petersen, BB Haines, J Chen, PA Sharp Rna 8 (6), 842-850, 2002 | 572 | 2002 |
| Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus TH Davis, TL Cuellar, SM Koch, AJ Barker, BD Harfe, MT McManus, ... Journal of Neuroscience 28 (17), 4322-4330, 2008 | 562 | 2008 |
| MicroRNA-responsive'sensor'transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression JH Mansfield, BD Harfe, R Nissen, J Obenauer, J Srineel, A Chaudhuri, ... Nature genetics 36 (10), 1079-1083, 2004 | 560 | 2004 |
| The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development E Hornstein, JH Mansfield, S Yekta, JKH Hu, BD Harfe, MT McManus, ... Nature 438 (7068), 671-674, 2005 | 545 | 2005 |
| MicroRNAs and cancer MT McManus Seminars in cancer biology 13 (4), 253-258, 2003 | 542 | 2003 |
Brian HarfeUniversity of FloridaVerified email at ufl.edu