| The expanding landscape of ‘oncohistone’mutations in human cancers BA Nacev, L Feng, JD Bagert, AE Lemiesz, JJ Gao, AA Soshnev, ... Nature 567 (7749), 473-478, 2019 | 346 | 2019 |
| Protein N-Terminal Processing: Substrate Specificity of Escherichia coli and Human Methionine Aminopeptidases Q Xiao, F Zhang, BA Nacev, JO Liu, D Pei Biochemistry 49 (26), 5588-5599, 2010 | 206 | 2010 |
| The epigenomics of sarcoma BA Nacev, KB Jones, AM Intlekofer, JSE Yu, CD Allis, WD Tap, M Ladanyi, ... Nature Reviews Cancer 20 (10), 608-623, 2020 | 181 | 2020 |
| The antifungal drug itraconazole inhibits vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, trafficking, and signaling in endothelial cells BA Nacev, P Grassi, A Dell, SM Haslam, JO Liu Journal of Biological Chemistry 286 (51), 44045-44056, 2011 | 147 | 2011 |
| Effect of nitroxoline on angiogenesis and growth of human bladder cancer JS Shim, Y Matsui, S Bhat, BA Nacev, J Xu, HC Bhang, S Dhara, KC Han, ... Journal of the National Cancer Institute 102 (24), 1855-1873, 2010 | 129 | 2010 |
| Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets BA Nacev, F Sanchez-Vega, SA Smith, CR Antonescu, E Rosenbaum, ... Nature Communications 13 (1), 3405, 2022 | 120 | 2022 |
| Mechanisms of aneuploidy in thyroid cancer cell lines and tissues: evidence for mitotic checkpoint dysfunction without mutations in BUB1 and BUBR1 B Ouyang, JA Knauf, K Ain, B Nacev, JA Fagin Clinical endocrinology 56 (3), 341-350, 2002 | 80 | 2002 |
| Simultaneous targeting of NPC1 and VDAC1 by itraconazole leads to synergistic inhibition of mTOR signaling and angiogenesis SA Head, WQ Shi, EJ Yang, BA Nacev, SY Hong, KK Pasunooti, RJ Li, ... ACS chemical biology 12 (1), 174-182, 2017 | 77 | 2017 |
| Itraconazole side chain analogues: structure–activity relationship studies for inhibition of endothelial cell proliferation, vascular endothelial growth factor receptor 2 … W Shi, BA Nacev, BT Aftab, S Head, CM Rudin, JO Liu Journal of medicinal chemistry 54 (20), 7363-7374, 2011 | 75 | 2011 |
| Oncohistone mutations enhance chromatin remodeling and alter cell fates JD Bagert, MM Mitchener, AL Patriotis, BE Dul, F Wojcik, BA Nacev, ... Nature chemical biology 17 (4), 403-411, 2021 | 71 | 2021 |
| High-throughput screen identifies novel inhibitors of cancer biomarker α-methylacyl coenzyme A racemase (AMACR/P504S) BAP Wilson, H Wang, BA Nacev, RC Mease, JO Liu, MG Pomper, ... Molecular cancer therapeutics 10 (5), 825-838, 2011 | 64 | 2011 |
| Impact of absolute stereochemistry on the antiangiogenic and antifungal activities of itraconazole W Shi, BA Nacev, S Bhat, JO Liu ACS medicinal chemistry letters 1 (4), 155-159, 2010 | 54 | 2010 |
| Synergistic inhibition of endothelial cell proliferation, tube formation, and sprouting by cyclosporin A and itraconazole BA Nacev, JO Liu PloS one 6 (9), e24793, 2011 | 39 | 2011 |
| Pilot study of bempegaldesleukin in combination with nivolumab in patients with metastatic sarcoma SP D’Angelo, AL Richards, AP Conley, HJ Woo, MA Dickson, M Gounder, ... Nature communications 13 (1), 3477, 2022 | 36 | 2022 |
| A phase II study of epacadostat and pembrolizumab in patients with advanced sarcoma CM Kelly, LX Qin, KA Whiting, AL Richards, V Avutu, JE Chan, P Chi, ... Clinical Cancer Research 29 (11), 2043-2051, 2023 | 34* | 2023 |
| Clinical, genomic, and transcriptomic correlates of response to immune checkpoint blockade-based therapy in a cohort of patients with angiosarcoma treated at a single center E Rosenbaum, CR Antonescu, S Smith, M Bradic, D Kashani, ... Journal for immunotherapy of cancer 10 (4), 2022 | 34 | 2022 |
| Clinical Outcome of Leiomyosarcomas With Somatic Alteration in Homologous Recombination Pathway Genes E Rosenbaum, P Jonsson, K Seier, LX Qin, P Chi, M Dickson, M Gounder, ... JCO precision oncology 4, 1350-1360, 2020 | 29 | 2020 |
| A calcineurin-independent mechanism of angiogenesis inhibition by a nonimmunosuppressive cyclosporin A analog BA Nacev, WK Low, Z Huang, TT Su, Z Su, H Alkuraya, D Kasuga, W Sun, ... Journal of Pharmacology and Experimental Therapeutics 338 (2), 466-475, 2011 | 26 | 2011 |
| Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells F Zhang, S Bhat, SB Gabelli, X Chen, MS Miller, BA Nacev, YL Cheng, ... Journal of medicinal chemistry 56 (10), 3996-4016, 2013 | 21 | 2013 |
| Phase II trial of imatinib plus binimetinib in patients with treatment-naive advanced gastrointestinal stromal tumor P Chi, LX Qin, B Nguyen, CM Kelly, SP D'Angelo, MA Dickson, ... Journal of Clinical Oncology 40 (9), 997-1008, 2022 | 19 | 2022 |
Jun O. LiuJohns Hopkins School of MedicineVerified email at jhu.edu
