| Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling N Li, A Batzer, R Daly, V Yajnik, E Skolnik, P Chardin, D Bar-Sagi, ... Nature 363 (6424), 85-88, 1993 | 1224 | 1993 |
| Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2 P Chardin, JH Camonis, NW Gale, L Van Aelst, J Schlessinger, MH Wigler, ... Science 260 (5112), 1338-1343, 1993 | 1107 | 1993 |
| Cyclic GMP-dependent protein kinase signaling pathway inhibits RhoA-induced Ca2+ sensitization of contraction in vascular smooth muscle V Sauzeau, H Le Jeune, C Cario-Toumaniantz, A Smolenski, ... Journal of Biological Chemistry 275 (28), 21722-21729, 2000 | 780 | 2000 |
| The ras protein family: evolutionary tree and role of conserved amino acids A Valencia, P Chardin, A Wittinghofer, C Sander Biochemistry 30 (19), 4637-4648, 1991 | 770 | 1991 |
| The mammalian G protein rhoC is ADP‐ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells. P Chardin, P Boquet, P Madaule, MR Popoff, EJ Rubin, DM Gill The EMBO journal 8 (4), 1087-1092, 1989 | 650 | 1989 |
| A human exchange factor for ARF contains Sec7-and pleckstrin-homology domains P Chardin, S Paris, B Antonny, S Robineau, S Béraud-Dufour, ... Nature 384 (6608), 481-484, 1996 | 619 | 1996 |
| Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine G Flatau, E Lemichez, M Gauthier, P Chardin, S Paris, C Fiorentini, ... Nature 387 (6634), 729-733, 1997 | 580 | 1997 |
| Four additional members of the ras gene superfamily isolated by an oligonucleotide strategy: molecular cloning of YPT-related cDNAs from a rat brain library. N Touchot, P Chardin, A Tavitian Proceedings of the National Academy of Sciences 84 (23), 8210-8214, 1987 | 544 | 1987 |
| Brefeldin A: the advantage of being uncompetitive P Chardin, F McCormick Cell 97 (2), 153-155, 1999 | 511 | 1999 |
| GEFs: structural basis for their activation of small GTP-binding proteins J Cherfils, P Chardin Trends in biochemical sciences 24 (8), 306-311, 1999 | 501 | 1999 |
| The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion A Zahraoui, N Touchot, P Chardin, A Tavitian Journal of Biological Chemistry 264 (21), 12394-12401, 1989 | 486 | 1989 |
| A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion CD Nobes, I Lauritzen, MG Mattei, S Paris, A Hall, P Chardin The Journal of cell biology 141 (1), 187-197, 1998 | 475 | 1998 |
| N-terminal hydrophobic residues of the G-protein ADP-ribosylation factor-1 insert into membrane phospholipids upon GDP to GTP exchange B Antonny, S Beraud-Dufour, P Chardin, M Chabre Biochemistry 36 (15), 4675-4684, 1997 | 474 | 1997 |
| Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling T Tominaga, E Sahai, P Chardin, F McCormick, SA Courtneidge, ... Molecular cell 5 (1), 13-25, 2000 | 461 | 2000 |
| Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the'effector'region. V Pizon, P Chardin, I Lerosey, B Olofsson, A Tavitian Oncogene 3 (2), 201-204, 1988 | 416 | 1988 |
| cAMP antagonizes p21ras‐directed activation of extracellular signal‐regulated kinase 2 and phosphorylation of mSos nucleotide exchange factor. BM Burgering, GJ Pronk, PC van Weeren, P Chardin, JL Bos The EMBO Journal 12 (11), 4211-4220, 1993 | 410 | 1993 |
| Inhibition of GTPase Activating Protein Stimulation of Ras-p21 GTPase by the Krev-1 Gene Product M Frech, J John, V Pizon, P Chardin, A Tavitian, R Clark, F McCormick, ... Science 249 (4965), 169-171, 1990 | 323 | 1990 |
| The ral gene: a new ras related gene isolated by the use of a synthetic probe. P Chardin, A Tavitian The EMBO journal 5 (9), 2203-2208, 1986 | 317 | 1986 |
| Common haplotype dependency of high G gamma-globin gene expression and high Hb F levels in beta-thalassemia and sickle cell anemia patients. D Labie, J Pagnier, C Lapoumeroulie, F Rouabhi, O Dunda-Belkhodja, ... Proceedings of the National Academy of Sciences 82 (7), 2111-2114, 1985 | 312 | 1985 |
| Function and regulation of Rnd proteins P Chardin Nature reviews Molecular cell biology 7 (1), 54-62, 2006 | 290 | 2006 |
