Articles with public access mandates - Gaofeng FanLearn more
Available somewhere: 27
Biallelic mutations in MYORG cause autosomal recessive primary familial brain calcification
XP Yao, X Cheng, C Wang, M Zhao, XX Guo, HZ Su, LL Lai, XH Zou, ...
Neuron 98 (6), 1116-1123. e5, 2018
Mandates: National Natural Science Foundation of China
Chimeric antigen receptor designed to prevent ubiquitination and downregulation showed durable antitumor efficacy
W Li, S Qiu, J Chen, S Jiang, W Chen, J Jiang, F Wang, W Si, Y Shu, ...
Immunity 53 (2), 456-470. e6, 2020
Mandates: Chinese Academy of Sciences, National Natural Science Foundation of China
NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells
Y Wang, F Wang, L Wang, S Qiu, Y Yao, C Yan, X Xiong, X Chen, Q Ji, ...
Cell reports 36 (6), 2021
Mandates: National Natural Science Foundation of China
Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness
J Chen, S Qiu, W Li, K Wang, Y Zhang, H Yang, B Liu, G Li, L Li, M Chen, ...
Cell research 33 (5), 341-354, 2023
Mandates: National Natural Science Foundation of China
Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease
P Gurung#, G Fan#, JR Lukens, P Vogel, NK Tonks, TD Kanneganti
Immunity, 2017
Mandates: US National Institutes of Health
Protein-tyrosine Phosphatase 1B Antagonized Signaling by Insulin-like Growth Factor-1 Receptor and Kinase BRK/PTK6 in Ovarian Cancer Cells*♦
G Fan, G Lin, R Lucito, NK Tonks
Journal of Biological Chemistry 288 (34), 24923-24934, 2013
Mandates: US National Institutes of Health
CRISPR system: Discovery, development and off-target detection
S Chen, Y Yao, Y Zhang, G Fan
Cellular signalling 70, 109577, 2020
Mandates: National Natural Science Foundation of China
De novo synthesis and salvage pathway coordinately regulate polyamine homeostasis and determine T cell proliferation and function
R Wu, X Chen, S Kang, T Wang, JNR Gnanaprakasam, Y Yao, L Liu, ...
Science Advances 6 (51), eabc4275, 2020
Mandates: US National Institutes of Health, V Foundation, USA
Protein-tyrosine Phosphatase and Kinase Specificity in Regulation of SRC and Breast Tumor Kinase*♦
G Fan, S Aleem, M Yang, WT Miller, NK Tonks
Journal of Biological Chemistry 290 (26), 15934-15947, 2015
Mandates: US National Institutes of Health
Suppression of protein tyrosine phosphatase N23 predisposes to breast tumorigenesis via activation of FYN kinase
S Zhang, G Fan, Y Hao, M Hammell, JE Wilkinson, NK Tonks
Genes & development 31 (19), 1939-1957, 2017
Mandates: US National Institutes of Health
HGF-independent regulation of MET and GAB1 by nonreceptor tyrosine kinase FER potentiates metastasis in ovarian cancer
G Fan, S Zhang, Y Gao, PA Greer, NK Tonks
Genes & development 30 (13), 1542-1557, 2016
Mandates: US National Institutes of Health, Canadian Institutes of Health Research
Peptidyl-prolyl isomerase Pin1 markedly enhances the oncogenic activity of the Rel proteins in the nuclear factor-κB family
G Fan, Y Fan, N Gupta, I Matsuura, F Liu, XZ Zhou, KP Lu, C Gélinas
Cancer research 69 (11), 4589-4597, 2009
Mandates: US National Institutes of Health
CAPERα is a novel Rel-TAD-interacting factor that inhibits lymphocyte transformation by the potent Rel/NF-κB oncoprotein v-Rel
J Dutta, G Fan, C Gélinas
Journal of virology 82 (21), 10792-10802, 2008
Mandates: US National Institutes of Health
Defective ubiquitin-mediated degradation of antiapoptotic Bfl-1 predisposes to lymphoma
G Fan, MJ Simmons, S Ge, J Dutta-Simmons, J Kucharczak, Y Ron, ...
Blood, The Journal of the American Society of Hematology 115 (17), 3559-3569, 2010
Mandates: US National Institutes of Health
Induction of senescence-associated secretory phenotype underlies the therapeutic efficacy of PRC2 inhibition in cancer
L Chu, Y Qu, Y An, L Hou, J Li, W Li, G Fan, BL Song, E Li, L Zhang, W Qi
Cell death & disease 13 (2), 155, 2022
Mandates: National Natural Science Foundation of China
Addressing the Enzyme-independent tumor-promoting function of NAMPT via PROTAC-mediated degradation
X Zhu, H Liu, L Chen, C Wu, X Liu, Y Cang, B Jiang, X Yang, G Fan
Cell Chemical Biology 29 (11), 1616-1629. e12, 2022
Mandates: National Natural Science Foundation of China
Key elements for designing and performing a CRISPR/Cas9-based genetic screen
W Shang, F Wang, G Fan*, H Wang*
Journal of Genetics and Genomics, 2017
Mandates: National Natural Science Foundation of China
Protein tyrosine phosphatase receptor type R (PTPRR) antagonizes the Wnt signaling pathway in ovarian cancer by dephosphorylating and inactivating β-catenin
Y Wang, J Cao, W Liu, J Zhang, Z Wang, Y Zhang, L Hou, S Chen, P Hao, ...
Journal of Biological Chemistry 294 (48), 18306-18323, 2019
Mandates: National Natural Science Foundation of China
A quantitative proteomics-based signature of platinum sensitivity in ovarian cancer cell lines
G Fan, KO Wrzeszczynski, C Fu, G Su, DJ Pappin, R Lucito, NK Tonks
Biochemical Journal 465 (3), 433-442, 2015
Mandates: US National Institutes of Health
FER-mediated phosphorylation and PIK3R2 recruitment on IRS4 promotes AKT activation and tumorigenesis in ovarian cancer cells
Y Zhang, X Xiong, Q Zhu, J Zhang, S Chen, Y Wang, J Cao, L Chen, ...
Elife 11, e76183, 2022
Mandates: National Natural Science Foundation of China
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