Current insights into the regulation of programmed cell death by NF-κB J Dutta, Y Fan, N Gupta, G Fan, C Gelinas Oncogene 25 (51), 6800-6816, 2006 | 578 | 2006 |
Regulation of programmed cell death by NF-κB and its role in tumorigenesis and therapy R Khosravi-Far, E White, Y Fan, J Dutta, N Gupta, G Fan, C Gélinas Programmed cell death in cancer progression and therapy, 223-250, 2008 | 199 | 2008 |
Biallelic mutations in MYORG cause autosomal recessive primary familial brain calcification XP Yao, X Cheng, C Wang, M Zhao, XX Guo, HZ Su, LL Lai, XH Zou, ... Neuron 98 (6), 1116-1123. e5, 2018 | 142 | 2018 |
Chimeric antigen receptor designed to prevent ubiquitination and downregulation showed durable antitumor efficacy W Li, S Qiu, J Chen, S Jiang, W Chen, J Jiang, F Wang, W Si, Y Shu, ... Immunity 53 (2), 456-470. e6, 2020 | 133 | 2020 |
Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist MJ Simmons, G Fan, WX Zong, K Degenhardt, E White, C Gelinas Oncogene 27 (10), 1421-1428, 2008 | 104 | 2008 |
NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells Y Wang, F Wang, L Wang, S Qiu, Y Yao, C Yan, X Xiong, X Chen, Q Ji, ... Cell reports 36 (6), 2021 | 73 | 2021 |
Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness J Chen, S Qiu, W Li, K Wang, Y Zhang, H Yang, B Liu, G Li, L Li, M Chen, ... Cell research 33 (5), 341-354, 2023 | 67 | 2023 |
Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease P Gurung#, G Fan#, JR Lukens, P Vogel, NK Tonks, TD Kanneganti Immunity, 2017 | 65 | 2017 |
Protein-tyrosine Phosphatase 1B Antagonized Signaling by Insulin-like Growth Factor-1 Receptor and Kinase BRK/PTK6 in Ovarian Cancer Cells*♦ G Fan, G Lin, R Lucito, NK Tonks Journal of Biological Chemistry 288 (34), 24923-24934, 2013 | 60 | 2013 |
CRISPR system: Discovery, development and off-target detection S Chen, Y Yao, Y Zhang, G Fan Cellular signalling 70, 109577, 2020 | 56 | 2020 |
De novo synthesis and salvage pathway coordinately regulate polyamine homeostasis and determine T cell proliferation and function R Wu, X Chen, S Kang, T Wang, JNR Gnanaprakasam, Y Yao, L Liu, ... Science Advances 6 (51), eabc4275, 2020 | 54 | 2020 |
Protein-tyrosine Phosphatase and Kinase Specificity in Regulation of SRC and Breast Tumor Kinase*♦ G Fan, S Aleem, M Yang, WT Miller, NK Tonks Journal of Biological Chemistry 290 (26), 15934-15947, 2015 | 53 | 2015 |
Suppression of protein tyrosine phosphatase N23 predisposes to breast tumorigenesis via activation of FYN kinase S Zhang, G Fan, Y Hao, M Hammell, JE Wilkinson, NK Tonks Genes & development 31 (19), 1939-1957, 2017 | 51 | 2017 |
HGF-independent regulation of MET and GAB1 by nonreceptor tyrosine kinase FER potentiates metastasis in ovarian cancer G Fan, S Zhang, Y Gao, PA Greer, NK Tonks Genes & development 30 (13), 1542-1557, 2016 | 51 | 2016 |
Peptidyl-prolyl isomerase Pin1 markedly enhances the oncogenic activity of the Rel proteins in the nuclear factor-κB family G Fan, Y Fan, N Gupta, I Matsuura, F Liu, XZ Zhou, KP Lu, C Gélinas Cancer research 69 (11), 4589-4597, 2009 | 47 | 2009 |
CAPERα is a novel Rel-TAD-interacting factor that inhibits lymphocyte transformation by the potent Rel/NF-κB oncoprotein v-Rel J Dutta, G Fan, C Gélinas Journal of virology 82 (21), 10792-10802, 2008 | 42 | 2008 |
Defective ubiquitin-mediated degradation of antiapoptotic Bfl-1 predisposes to lymphoma G Fan, MJ Simmons, S Ge, J Dutta-Simmons, J Kucharczak, Y Ron, ... Blood, The Journal of the American Society of Hematology 115 (17), 3559-3569, 2010 | 37 | 2010 |
Induction of senescence-associated secretory phenotype underlies the therapeutic efficacy of PRC2 inhibition in cancer L Chu, Y Qu, Y An, L Hou, J Li, W Li, G Fan, BL Song, E Li, L Zhang, W Qi Cell death & disease 13 (2), 155, 2022 | 31 | 2022 |
Repression of B-cell linker (BLNK) and B-cell adaptor for phosphoinositide 3-kinase (BCAP) is important for lymphocyte transformation by rel proteins N Gupta, J Delrow, A Drawid, AM Sengupta, G Fan, C Gélinas Cancer research 68 (3), 808-814, 2008 | 31 | 2008 |
Electrochemical investigation of redox thermodynamics of immobilized myoglobin: Ionic and ligation effects X Liu, Y Huang, W Zhang, G Fan, C Fan, G Li Langmuir 21 (1), 375-378, 2005 | 31 | 2005 |